First person receives Pfizer Covid-19 vaccine in UK • Hacker News Board

Re: First person receives Pfizer Covid-19 vaccine in UK

#401

Post by hhas01 » Sat, Dec 12, 2020, 7:38 PM UTC

nkohari wrote: post #399

hhas01 wrote: post #398

Earlier quoted context omitted.

“You know what I meant” No. I am not a mindreader. And “vaccines are injected into the bloodstream” is a standard antivax lie. Yes there’s a risk in receiving a vaccine, just as there’s a risk in receiving any prophylactic/therapeutic treatment, but severe side-effects are closer to 1-in-100K to 1-in-a-million. Compared to a disease that is currently killing 2-in-100, with significant sequelae likely much higher. I’m…

If you had actually read what I wrote thoughtfully -- instead of falling over yourself to type a glib reply as fast as you could get it out -- it would have been easy to recognize that I am clearly not anti-vaccine, nor was I suggesting that side effects are common. I said both of those things explicitly. If your goal is actually to educate others, then educate others. Replying with snark achieves nothing but tempora…

Yes I read your post, and yes it was poorly worded. Take the tip and move on.

Re: First person receives Pfizer Covid-19 vaccine in UK

#402

Post by drjet » Sun, Dec 13, 2020, 6:35 PM UTC

LatteLazy wrote: post #164

mikepechadotcom wrote: post #32

I feel like mRNA vaccines have huge potential, but I am really, really concerned about potential side effects. Does anyone know which other helper-substances are inside the vaccine, besides the RNA?

Ingredients list: >6. PHARMACEUTICAL PARTICULARS >6.1 List of excipients ALC-0315 = (4-hydroxybutyl) azanediyl)bis (hexane-6,1-diyl)bis(2-hexyldecanoate), ALC-0159 = 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 1,2-Distearoyl-sn-glycero-3-phosphocholine, cholesterol, potassium chloride, potassium dihydrogen phosphate, sodium chloride, disodium hydrogen phosphate dihydrate, sucrose, water for injections S…

You need to be looking at the lipid ingredients that the mRNA is delivered in. Polyethylene glycol causes allergic and other reactions. The 1,2 Distearoyl... is associated with immune suppression due to destruction of lymphocyte membranes within 8 hrs of administration. Still researching the 4-hydroxybutyl....

Re: First person receives Pfizer Covid-19 vaccine in UK

#403

Post by drjet » Sun, Dec 13, 2020, 6:44 PM UTC

zebrafish wrote: post #235

LatteLazy wrote: post #193

Earlier quoted context omitted.

Thanks! Any idea if thoseipid vesicles are "standard"? In case you care, I have no objections to the vaccine. I'm too young (36 and not working in care) to get it any time soon. But I'd take it tomorrow if it were available for me.

No, the major difference in the Pfizer and Moderna vaccines are in the makeup of the lipid nanoparticle. Here's an article from Moderna last year on biodegradability of the LNPs they've developed. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383180/

Thanks for this article. I can see both vaccines consider the use of PEG to be important. Still looking for the other lipid ingredients in the Moderna vaccine.

Re: First person receives Pfizer Covid-19 vaccine in UK

#404

Post by h_anna_h » Fri, Dec 18, 2020, 7:20 AM UTC

learc83 wrote: post #389

h_anna_h wrote: post #361

Earlier quoted context omitted.

I would certainly expect that to be the case in a sane system. Sadly I have seen too many bureaucratic insanities around so it does not seem far-fetched to me. "and added to a database that reported COVID deaths are pulled from." database or excel spreadsheet? https://news.ycombinator.com/item?id=24689247 I don't use facebook, my sources are my aunt (my uncle died 5 days ago due to falling and hitting his head, combi…

I have no idea what goes on in Greece or what incentive people would have to do that. But excess death numbers are higher than COVID deaths everywhere, so the numbers aren't likely that far off. Also my fiancee, an ER doctor, assures me that this isn't the case in the US.

Apparently there were less deaths in greece from january-sept 2020 compared to january-sept 2019 so I don't really know what to say. https://www.cnn.gr/oikonomia/story/242950/elstat-ligoteroi-o...