I would use Tox and any of its clients with caution. At one point in time, your friends would be able to execute arbitrary shell commands on your PC if you were running utox and accepted a file download. Even with large security concerns like this, the lead developer believes Tox and uTox is secure because he reads the code he wrote himself (none the less git history is filled with bug fixes he clearly missed in his…
Your claims ring true for vast majority of new, COMSEC schemes. Far as Tox, this is what I found on their GitHub page: "Current build status: build failing." I'll add that NSA and malware authors have 0-days on the platforms the tool will likely run on. It will be bypassed like all others on such platforms.