Ho does one just summon a group of highly skilled researchers to help out a baby? Like, how did these researchers get paid?
Scientists edited genes in a living person and saved his life
41–47 of 47 posts
Re: Scientists edited genes in a living person and saved his life
#42Very dumb question, but how exactly does gene therapy work in vivo? Don't you have to modify every cell (or affected type of cell) with a new copy of the DNA? How does that actually.... happen?
If the affected protein is actively causing problems, then you'd need to get most of the cells. But if it's just inert and not doing its job then you only need to get enough cells to get the production of the right version up to a somewhat functional level.
Re: Scientists edited genes in a living person and saved his life
#43Very dumb question, but how exactly does gene therapy work in vivo? Don't you have to modify every cell (or affected type of cell) with a new copy of the DNA? How does that actually.... happen?
It's like trying to persuade enough people (cell) to change their mind so a social revolution takes place (cure). The argument (gene vector) must be very popular.
Re: Scientists edited genes in a living person and saved his life
#44Your genes seem to be out of date, there are several security updates pending. The download will be 3.2 Gb and will take about 3 seconds..... Because this is a security update you can not refuse it. If you are commanding a vehicle park it now or switch to autopilot. Commencing update in 10, 9, 8, ...
I updated to version 10.5.7 and now I see Samsung ads in my peripheral vision, wtf
I am now nicotine addicted without smoking a single cigarette.
Re: Scientists edited genes in a living person and saved his life
#45Earlier quoted context omitted.
̶I̶ ̶t̶h̶i̶n̶k̶ ̶h̶e̶ ̶a̶c̶t̶u̶a̶l̶l̶y̶ ̶g̶e̶n̶e̶t̶i̶c̶a̶l̶l̶y̶ ̶e̶n̶g̶i̶n̶e̶e̶r̶e̶d̶ ̶h̶i̶s̶ ̶g̶u̶t̶ ̶b̶a̶c̶t̶e̶r̶i̶a̶ ̶r̶a̶t̶h̶e̶r̶ ̶t̶h̶a̶n̶ ̶a̶n̶y̶ ̶o̶f̶ ̶h̶i̶s̶ ̶o̶w̶n̶ ̶c̶e̶l̶l̶s̶ ̶t̶h̶e̶r̶e̶,̶ ̶r̶i̶g̶h̶t̶?̶ EDIT: Above is false. Went back and checked and I had mis-remembered the video.
From the video, it sounds like he engineered his own cells. Using a virus that is known for transferring genetic material into other organisms, he added a gene for producing lactase, and then ate it. I suppose that would affect both his gut bacteria and his own cells. But it lasted for ~1.5 years, which probably indicates that it truly was his cells. Also he seems to know what he's talking about, and he claims it was…
Could be placebo though?
Re: Scientists edited genes in a living person and saved his life
#46The facts of life... to make an alteration in the evolvement of an organic life system is fatal. A coding sequence cannot be revised once it's been established.
Why not?
Because by the second day of incubation, any cells that have undergone reversion mutation give rise to revertant colonies, like rats leaving a sinking ship; then the ship... sinks.
What about EMS-3 recombination?
We've already tried it - ethyl, methane, sulfinate as an alkylating agent and potent mutagen; it created a virus so lethal the subject was dead before it even left the table.
Then a repressor protein, that would block the operating cells.
Wouldn't obstruct replication; but it does give rise to an error in replication, so that the newly formed DNA strand carries with it a mutation - and you've got a virus again... but this, all of this is academic.
You were made as well as we could make you.
Re: Scientists edited genes in a living person and saved his life
#47Earlier quoted context omitted.
̶I̶ ̶t̶h̶i̶n̶k̶ ̶h̶e̶ ̶a̶c̶t̶u̶a̶l̶l̶y̶ ̶g̶e̶n̶e̶t̶i̶c̶a̶l̶l̶y̶ ̶e̶n̶g̶i̶n̶e̶e̶r̶e̶d̶ ̶h̶i̶s̶ ̶g̶u̶t̶ ̶b̶a̶c̶t̶e̶r̶i̶a̶ ̶r̶a̶t̶h̶e̶r̶ ̶t̶h̶a̶n̶ ̶a̶n̶y̶ ̶o̶f̶ ̶h̶i̶s̶ ̶o̶w̶n̶ ̶c̶e̶l̶l̶s̶ ̶t̶h̶e̶r̶e̶,̶ ̶r̶i̶g̶h̶t̶?̶ EDIT: Above is false. Went back and checked and I had mis-remembered the video.
Is there a reason why I'm seeing squares between each of the characters in your message? It's making it pretty hard to read... I'm using Chrome on Android
The text is crossed out using Unicode combining characters of a strikethrough. This allows it to display without any specific formatting support, but it does require that the font support those characters. The font you're using doesn't support the characters, so it displays boxes, instead.