Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Excitable cells

jenevoldsen.com

Post reply on HN
Print view View original

41–50 of 51 posts

Re: Excitable cells

#41

Post by eknkc »

rdegges wrote: post #19
eknkc wrote: post #14

I have frequent ectopic beats that I feel as a flutter / heavy beat on my chest. The doc says it won't kill me but it is extremely uncomfortable at times. This has been a great material to learn about the inner workings of heart cells. BTW Here's an ECG from my Apple Watch showing 3 such beats (you can't miss them): https://link.ekin.dev/l1Vc3Gdf If you happen to have these, just get checked out by a cardiologist. Th…

I had something similar for many years (triggered by an episode of afib brought-on by triggering my vagus nerve). The one thing that has helped me fully get rid of these (after YEARS of trial-and-error) was getting onto beta blockers (Propranolol). These have COMPLETELY gotten rid of my ectopic beats and also helped me deal with the health anxiety. If you ever want to talk, feel free to hit me up (contact info in pro…

Yeah, I’ve been on propranolol and then metoprolol but they don’t seem to do much in terms of reducing ectopics. Currently on metoprolol though.

I’ve had an echo, stress ecg and then a ct angiogram. Everything is physically fine so at this point I mostly ignore them cause at least I know they are not an immediate danger.

Thanks!

Re: Excitable cells

#42

Post by throwaway7783 »

rdegges wrote: post #19
eknkc wrote: post #14

I have frequent ectopic beats that I feel as a flutter / heavy beat on my chest. The doc says it won't kill me but it is extremely uncomfortable at times. This has been a great material to learn about the inner workings of heart cells. BTW Here's an ECG from my Apple Watch showing 3 such beats (you can't miss them): https://link.ekin.dev/l1Vc3Gdf If you happen to have these, just get checked out by a cardiologist. Th…

I had something similar for many years (triggered by an episode of afib brought-on by triggering my vagus nerve). The one thing that has helped me fully get rid of these (after YEARS of trial-and-error) was getting onto beta blockers (Propranolol). These have COMPLETELY gotten rid of my ectopic beats and also helped me deal with the health anxiety. If you ever want to talk, feel free to hit me up (contact info in pro…

Daily dose of magnesium supplements has made it tolerable for me, when beta blockers (carvedilol) didn't help much.

Re: Excitable cells

#43

Post by danwills »

Kalabasa wrote: post #3

Learned about the heart today! Thank you! I wonder what other types of cells / tissues can be simulated by cellular automata?

I think many types can if you broaden the definition of automata to include 'reaction diffusion' you can even simulate things like the Schrödinger equation under a RD scheme! (there are some examples in gollygang/Ready).

RD was invented by Alan Turing as a way to model animal coat patterns too, and I think it's exceptionally good at that (I did a talk at Houdini Hive SiggraphAsia2019 about it: https://youtu.be/K_7TkoIkFhk?si=afhcjZ8TeysNJxRH)

Re: Excitable cells

#44

Post by danwills »

owenpalmer wrote: post #27
Kalabasa wrote: post #3

Learned about the heart today! Thank you! I wonder what other types of cells / tissues can be simulated by cellular automata?

I was thinking the same thing. I need more simulations like this!

Definitely have a look at gollygang/Ready I reckon! There are some really fascinating things in the pattern library (including some that I contributed).

https://github.com/GollyGang/ready

Re: Excitable cells

#45

Post by BenFranklin100 »

Off topic, but I’v always wanted to download web pages like this that contain interactive plots for self-study or later reference. Solutions like SingleFile or Zotero never work though.

Any suggestions?

Re: Excitable cells

#46

Post by fraserphysics »

johannes_ne wrote: post #38

Thank you for all the kind responses. I also want to make a similar article, where I calculate an ECG for the simulation, and then make and explain the changes necessary to make the ECG look realistic. A main challenge will be that the depolarization has to happen very fast relative to the repolarization, which may be computationally difficult for a cell-based simulation.

Also cool would be the inverse. Going from ECG to plausible simulated RD dynamics.

Re: Excitable cells

#47

Post by 0_____0 »

eknkc wrote: post #14

I have frequent ectopic beats that I feel as a flutter / heavy beat on my chest. The doc says it won't kill me but it is extremely uncomfortable at times. This has been a great material to learn about the inner workings of heart cells. BTW Here's an ECG from my Apple Watch showing 3 such beats (you can't miss them): https://link.ekin.dev/l1Vc3Gdf If you happen to have these, just get checked out by a cardiologist. Th…

I used to get them occasionally. A few years back I started doing loads of cardio exercise and I noticed a while back that I hadn't had the flutter for a long time. I always wondered if it was due to increased cardiac fitness.

Re: Excitable cells

#48

Post by channel_t »

pscanf wrote: post #9

Exciting simulations! :) And an excellent explanation. From time to time I get episodes of sudden tachycardia¹. It's a very strange feeling: one second everything is fine, the next my heart jumps in my throat and starts beating at 230 bpm (not a typo). After a while, just as quickly as it came, the tachycardia goes away and I'm back at whatever HR I was before the trigger. If it doesn't go away by itself, breathing i…

I have PSVT. I think it started for me around the age of 17 and was always pretty short-lived and infrequent, often with years between episodes. A couple years ago, chronic stress and lifestyle stuff began to catch up with me and the episodes started happening a few times a week, so I'm now prescribed Metoprolol as a pill in a pocket thing to deal with it. Generally speaking, as long as sleep, diet, and basic exercise are in order--and alcohol/caffeine consumption are kept low--it just doesn't happen. It also can almost always be remedied with some simple vagus nerve exercises. All of that can be tough to manage sometimes though, so I'm very seriously considering getting an ablation soon. The doctors have told me that it's not a particularly dangerous condition as long as you're an otherwise healthy individual, but it's definitely still terrifying and can't be good for you either.

Re: Excitable cells

#49

Post by benterix »

UncleOxidant wrote: post #39
rdegges wrote: post #19

Earlier quoted context omitted.

I had something similar for many years (triggered by an episode of afib brought-on by triggering my vagus nerve). The one thing that has helped me fully get rid of these (after YEARS of trial-and-error) was getting onto beta blockers (Propranolol). These have COMPLETELY gotten rid of my ectopic beats and also helped me deal with the health anxiety. If you ever want to talk, feel free to hit me up (contact info in pro…

> an episode of afib brought-on by triggering my vagus nerve I get ectopic beats when I've got trapped gas in the stomach. Sounds weird, but generally when I get them I realize I need to stand up (because I've usually been sitting with bad posture which leads to the trapped gas) and have a large belch and then it calms down. I mentioned this to my doc and he said it was Roemheld syndrome ( https://en.wikipedia.org/wi…

Yeah I got quite scared when it happened for the first time.
Post reply on HN