this is spam. he's optimizing his health. dont hate the guy for trying to improve the health of himself and others.
The Most Expensive Eating Disorder
41–50 of 80 posts
Re: The Most Expensive Eating Disorder
#42Informative article! I did have a question about this passage though.
"It seems that he is spending a lot of his time & effort on maintaining his hair (huge kudos for admitting that!). If his body was functioning like an 18-year old he should not need to do that. If Bryan really set back his true aging clock he probably would not be battling with ongoing hair loss (as he most likely did not battle hair loss 20 years prior), or at least it would stop (which does not seem to be the case)."
Is this true? I suppose it's a question of what one defines as aging but I thought male pattern baldness resulted from hair follicles physically shrinking in response to exposure to androgens. That's a very different process than an accumulation of senescent / poorly differentiated cells, which is what I have always heard described as the key hallmark of aging
Re: The Most Expensive Eating Disorder
#43Earlier quoted context omitted.
I'm not super well versed but my understanding is that that's right, with your actual DHT levels being the third variable. There are other non-hormonal causes of hair loss, like alopecia areata, but they're much less common. DHT damages the hair follicles that are sensitive to it, causing them to grow back thinner after each growth and shedding cycle (which is typically a few years). As a result most men don't have v…
It's interesting because there are medicines that can block DHT or reduce it's effectiveness, but they have other negative side-effects. It's almost like if you have this gene and are a healthy man, you should loose your hair - I wonder what the evolutionary mechanism of that is.
None, and in fact it has been proposed that men suffering from AGA, especially if it's early onset, may have something equivalent to polycystic ovarian syndrome in women.
https://pubmed.ncbi.nlm.nih.gov/28711970/
The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of early onset (Re: The Most Expensive Eating Disorder
#44From the author: Some of the strategies I employ include: I put a prime on sleep, diet, and exercise. I optimize my hormones. I downregulate the mTOR pathway. I take pharmaceutical drugs aimed at improving metabolic health. I employ several behavioral, hormonal, and pharmaceutical strategies to delay cancer, atherosclerosis, and neurodegeneration. I cleared my body of (some) senescent cells with senolytic drugs. I mo…
The critique was not his use of pharmaceuticals. The author even mentioned he adopted a supplement straight out of Bryan's regimen.
Re: The Most Expensive Eating Disorder
#45Why am I expected to know who Bryan Johnson is?
Re: The Most Expensive Eating Disorder
#46I was so fit in my 30's, I measured a heart rate of like 38 sitting in a work meeting. I could amuse nurses in an emergency room by clipping my finger into the machine, instead of the patient I was with, to set off the alarms with the low numbers. One time I came in with some severe stomach flu. I was lying on my back and the nurse said to another, "Come here! Look this guy is so thin, you can see his heart beating i…
there’s a famous story about Wayne Gretzky’s (170 lb weight, 140 lb max bench) recuperative abilities being so powerful that the Oilers’ trainers thought the testing machine was broken.
Re: The Most Expensive Eating Disorder
#47Earlier quoted context omitted.
Are you an MD like the author? And even if not - what is your rebuttal here?
I'm not an MD. Jumping from "he blinks a lot in interviews" to "his lacrimal ducts cannot manufacture the lipid portion of tear fluid" is silly. It's like something from a TV show doctor. He's being interviewed and some people blink a lot when they're nervous!
> He's being interviewed and some people blink a lot when they're nervous!
We're talking about a guy that chooses to be in front of a camera, weekly, for millions of views.
Re: The Most Expensive Eating Disorder
#48I was so fit in my 30's, I measured a heart rate of like 38 sitting in a work meeting. I could amuse nurses in an emergency room by clipping my finger into the machine, instead of the patient I was with, to set off the alarms with the low numbers. One time I came in with some severe stomach flu. I was lying on my back and the nurse said to another, "Come here! Look this guy is so thin, you can see his heart beating i…
I strength train two or three times a week and my heart rate last night was 42. I think a low heart rate is at least partly genetic. Definitely agree about the dizziness.
Re: The Most Expensive Eating Disorder
#49The most recent thing I've heard him say is his body fat percentage is 10% currently.
It's odd that's not reflected in the article, and the conclusions are very much different if that's the case no?
Re: The Most Expensive Eating Disorder
#50Informative article! I did have a question about this passage though. "It seems that he is spending a lot of his time & effort on maintaining his hair (huge kudos for admitting that!). If his body was functioning like an 18-year old he should not need to do that. If Bryan really set back his true aging clock he probably would not be battling with ongoing hair loss (as he most likely did not battle hair loss 20 years…
it's kind of bullshit because plenty of guys lose some/most of their hair in their teens