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Ozempic will disrupt big tobacco, candy companies, and alcohol brands

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Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#41

Post by znpy »

Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

> So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear.

It isn't that different from what happened with vapes and e-cigs, and they were even worse (nicotine-based, explicitly harmful).

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#42

Post by adam_arthur »

raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

You can buy pharmacy compounded semaglutide through online portals, e.g. Ro

It's $450/month out of pocket (no insurance coverage)

Therefor, there will actually be price competition and we should see pretty cheap prices in the coming years.

I'm not sure exactly why pharmacies are free to compound it independently. I guess whatever patents exist on Ozempic/Wegovy etc aren't sufficient to squash competition.

The $1000/month for Ozempic is purely a name brand markup. I'd guess we'll see prices closer to $100/month for the compounded variants within a few years

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#43

Post by SolarNet »

s1k3s wrote: post #31
raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

> As Chairman of the Senate Committee on Health, Education, Labor, and Pensions (HELP), I am calling on Novo Nordisk to lower the list price of Ozempic – and the related drug Wegovy – in America to no more than what they charge for this drug in Canada. I'm not aware of how legislation works in US but I feel like a senator should have more power than just "calling on" a company?

Eh, calling on a company to do a thing is some mix between public fact finding and threat here.

It allows the public to comment and maybe the senator will like the public support they are getting. Alternatively a pharma lobbyist will show up and toss them a few hundred thousand in campaign contribution promises. And they'll weight the relative value of those things. Depending on how that goes they (or another senator seeing this play out) will actually make an issue of it and it will start the more formal processes.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#44

Post by DiabloD3 »

s1k3s wrote: post #31
raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

> As Chairman of the Senate Committee on Health, Education, Labor, and Pensions (HELP), I am calling on Novo Nordisk to lower the list price of Ozempic – and the related drug Wegovy – in America to no more than what they charge for this drug in Canada. I'm not aware of how legislation works in US but I feel like a senator should have more power than just "calling on" a company?

He is asking them, using the official power of his office, to do the right thing so legislation doesn't need to be drafted. Either they choose to do the right thing today and not be subject to regulations, or they can get punished with regulations at some point in the future.

If you think things happen differently in Canada, you don't understand how the sausage is made.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#45

Post by fooker »

odiroot wrote: post #38
akgoel wrote: post #7

Earlier quoted context omitted.

When I was on Ozempic, I just didn't want the milkshake. It rewires all reward centers.

If they invent something like this but for procrastination, they'd get a Nobel prize.

Adderall is used pretty effectively for this.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#46

Post by aleksiy123 »

odiroot wrote: post #38
akgoel wrote: post #7

Earlier quoted context omitted.

When I was on Ozempic, I just didn't want the milkshake. It rewires all reward centers.

If they invent something like this but for procrastination, they'd get a Nobel prize.

Adderall and Vyvanse?

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#47

Post by Spooky23 »

raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

There’s a pill form called Rybelsus that works similarly, but has some gotchas. Namely you need to take with water when you wake up and eat nothing for 30m.

From a lifetime value perspective, I think it’s priced cheap. This drug is a miracle drug and is going to eliminate a lot of suffering and healthcare costs.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#48

Post by onionisafruit »

tyre wrote: post #19
Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

Semaglutide has been on the market since 2017 and clinical trials commenced in 2008. So we have a fair amount of data on longer-term users. It wasn't being used for general obesity until recently.

My doctor has been prescribing it for obesity for about five years.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#49

Post by alpinisme »

s1k3s wrote: post #31
raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

> As Chairman of the Senate Committee on Health, Education, Labor, and Pensions (HELP), I am calling on Novo Nordisk to lower the list price of Ozempic – and the related drug Wegovy – in America to no more than what they charge for this drug in Canada. I'm not aware of how legislation works in US but I feel like a senator should have more power than just "calling on" a company?

He would if he had broader congressional support, but opposing forces are strong (lobbies, pro-market ideology, etc)

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#50

Post by someplaceguy »

odiroot wrote: post #38
akgoel wrote: post #7

Earlier quoted context omitted.

When I was on Ozempic, I just didn't want the milkshake. It rewires all reward centers.

If they invent something like this but for procrastination, they'd get a Nobel prize.

Oh God, imagine the self-, peer, and top-down pressure to take that, both for students and working adults.
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