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Earlier quoted context omitted.
Wouldn’t it be cool if we could periodically trigger waves like this to refresh the brain and maybe require less (or no) sleep! I have no expertise in this area I’m just a dreamer :)
For companies it'd be a dream. 1/4 more awake time is 1/4 more time to buy stuff and watch content and ads. Or work longer hours. Gonna go back to sleep now.
Earlier quoted context omitted.
Checked and it was published through Nature: Jiang-Xie, LF., Drieu, A., Bhasiin, K. et al. Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance. Nature 627, 157–164 (2024). https://doi.org/10.1038/s41586-024-07108-6 Every Uni should have access through your library system.
Yes, it was published through Nature. But what stops Univ' site to have original research paper available for download? Nature magazine is just a distribution channel (they did not sponsor the research so should not have exclusive rights on it). Left college long time ago; and do not have access to any library system.
Earlier quoted context omitted.
Checked and it was published through Nature: Jiang-Xie, LF., Drieu, A., Bhasiin, K. et al. Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance. Nature 627, 157–164 (2024). https://doi.org/10.1038/s41586-024-07108-6 Every Uni should have access through your library system.
I think the point was that every member of the public should have access to publicly funded research at least through the university's website, rather than at least everyone currently in universities should have access.
Earlier quoted context omitted.
I can't find free access to the full paper, but here's the abstract (afraid I'm not knowledgeable enough to add to or explain any of it): " The accumulation of metabolic waste is a leading cause of numerous neurological disorders, yet we still have only limited knowledge of how the brain performs self-cleansing. Here we demonstrate that neural networks synchronize individual action potentials to create large-amplitud…
>Chemogenetic flattening of these high-energy ionic waves largely impeded cerebrospinal fluid infiltration into and clearance of molecules from the brain parenchyma. Sounds like unsync'd brain waves, (being awake) impedes cerebrospinal fluid flow through the brain. When asleep, neurons sync their action potentials, acting like a ionized fluid pump, moving old dirty cerebrospinal fluid out, and allowing new, clean in.…
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Well, thats basically the trope of every Cybernetic design, with the connectors comming out the back of head/spine...
Like a continual wash which keeps you in this suspended hyper-aware, but calm, rested and focused mental state.
This is why cyborgs have such incredible reflexes.
We need to figure out what activity or thought creates waves most similar to the cleaning function. Maybe it’s dreaming? Dreaming by my experience is tedious and not restful… I have 4-6 dreams every night and never feel like I’m truly asleep. Shouldn’t be hard to figure out with an EKG and a decent graph to see what your aiming for.
Earlier quoted context omitted.
Checked and it was published through Nature: Jiang-Xie, LF., Drieu, A., Bhasiin, K. et al. Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance. Nature 627, 157–164 (2024). https://doi.org/10.1038/s41586-024-07108-6 Every Uni should have access through your library system.
I think the point was that every member of the public should have access to publicly funded research at least through the university's website, rather than at least everyone currently in universities should have access.
So garbage collection is not such a bad idea after all...
Is anyone more knowledgeable able to interpret the paper beyond ‘brain waves wash toxins’? Are they actually responsible for the observed activity, or do they merely trigger some ‘flushing’ mechanism inherent to the cells? Or, are the waves a result of that process?
I can't find free access to the full paper, but here's the abstract (afraid I'm not knowledgeable enough to add to or explain any of it): " The accumulation of metabolic waste is a leading cause of numerous neurological disorders, yet we still have only limited knowledge of how the brain performs self-cleansing. Here we demonstrate that neural networks synchronize individual action potentials to create large-amplitud…
This line is the money shot. An action potential is the variable electrical charge of a neuron, and they maintain that charge by containing a certain concentration of ions relative to the surrounding cerebrospinal fluid. This paper proposes that neurons synchonise their charge state, which forces ions to flow in or out of the neurons in bulk, the movement of these ions causing the cerebrospinal fluid to move around, clearing out the accumulated debris.
Earlier quoted context omitted.
Wouldn’t it be cool if we could periodically trigger waves like this to refresh the brain and maybe require less (or no) sleep! I have no expertise in this area I’m just a dreamer :)
For companies it'd be a dream. 1/4 more awake time is 1/4 more time to buy stuff and watch content and ads. Or work longer hours. Gonna go back to sleep now.
it could be used in endurance/focused events. high stress relief, traumatic brain injury - like immediate induce afte cte event in foot ball
head trauma in car accident
ODs etc...
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When I was a baby, and I would get ill, my mom would calm me and put me to sleep - and I would sleep for an extended period and my mom would say that I would wake up fully well.
If this could be induced in infants going through trauma's such as a surgery, where inducing natural brain-flush instead of pumping a tiny body full of "medicine" this might be great for their long term mental development outside of having medicines in them when growing extremely fast.