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Man in remission from blood cancer and HIV after remarkable treatment

theguardian.com

41–50 of 61 posts

Re: Man in remission from blood cancer and HIV after remarkable treatment

#41

Earlier quoted context omitted.

Indeed. A common question people have is "is being dead healthier than being alive but sick?" I suspect we may never know the answer to this. Science cannot find this truth.

A common question people have is "is being dead healthier than being alive but sick?" You think this is a 'common question'?

Yeah, a lot of people are saying that it's a question they think about.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#42
post #25

These sort of articles pop up every few months and make people hopeful for a cure, but this is sadly unlikely to ever be a viable one. Stem cell transplantation is a standard treatment for several blood cancers, but will almost certainly never be a standard HIV treatment for anyone except patients who need a transplantation anyway, for one single reason: with modern medicine, living with transplanted stem cells is si…

The avenue towards making this a viable, routine cure for HIV is by performing a “transplant” of the patient’s own immune stem cells that have been genetically modified to carry the anti-HIV genes. That avoids (if done right) the horrific autoimmune challenges you describe, but like everything else it comes with its own technical challenges that are still being worked out. (I think https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935568/ is a good review of the whole idea.) To me (though I’m not an HIV researcher by any means!) this sounds like the most promising shot we have at regularly curing the disease.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#43
post #25

These sort of articles pop up every few months and make people hopeful for a cure, but this is sadly unlikely to ever be a viable one. Stem cell transplantation is a standard treatment for several blood cancers, but will almost certainly never be a standard HIV treatment for anyone except patients who need a transplantation anyway, for one single reason: with modern medicine, living with transplanted stem cells is si…

This is correct. I have an extremely rare leukemia This is not something you're going to want for something as apparently treatable as HIV.

I hope your die falls on one of the 2 good sides.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#44
post #34

Earlier quoted context omitted.

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As an atheist, I would say that the opinions of these organisations do matter, insofar as they are likely to influence political opinion in the countries where they have significant followers.

Separation of church and state matters

Re: Man in remission from blood cancer and HIV after remarkable treatment

#46
post #20

Earlier quoted context omitted.

On our underfunded government socialized healthcare systems? No way. Those who are minted go to the US or Switzerland for best cutting edge treatments and prosthetics.

Only 5 patients worldwide has had this dual treatment so far, as far I understand - it's experimental. There's basically one clinic running tests on this specific treatment. Stem cell treatments for this kind of cancer, however, is on the UK NHS's list of treatments when the first line treatments do not get an optimal response, and from what I can see they've been in the guidelines since at least 2020. Given the NHS…

The second patient to be cured this way was from London.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#47
post #25

These sort of articles pop up every few months and make people hopeful for a cure, but this is sadly unlikely to ever be a viable one. Stem cell transplantation is a standard treatment for several blood cancers, but will almost certainly never be a standard HIV treatment for anyone except patients who need a transplantation anyway, for one single reason: with modern medicine, living with transplanted stem cells is si…

This seems like a little bit of a fearmongering. We're slowly understanding GVHD and GVT issues, suppressing one while keeping the other. The frequency of GVHD has been going down over time as we better match donors to the patient.

There are a lot of treatments that started off just like this. For things we thought we would never have a proper cure for, until we gradually understood how treatment worked and how to refine that treatment.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#48

Earlier quoted context omitted.

A common question people have is "is being dead healthier than being alive but sick?" You think this is a 'common question'?

Yeah, a lot of people are saying that it's a question they think about.

Who is saying that it's a question they think about?

Re: Man in remission from blood cancer and HIV after remarkable treatment

#49

Earlier quoted context omitted.

Some highlights after reading the Wikipedia article on Stem cell controversy: - Austria, Denmark, France, Germany, Portugal and Ireland do not allow the production of embryonic stem cell lines - The creation of embryonic stem cell lines is permitted in Finland, Greece, the Netherlands, Sweden, and the United Kingdom - Arkansas, Indiana, Louisiana, North Dakota and South Dakota have passed laws to "prohibit the creati…

[flagged]

Isn't it better to actually consider their arguments than dismissing them for being just who they are? Many of these people are extremely skilled in philosophy and ethics

Although their arguments often are based on religious grounds that you may dismiss, you may also find that similar principles can be derived from humanistic traditions alone.

Re: Man in remission from blood cancer and HIV after remarkable treatment

#50
post #18

Stem cells seem to have this potential to cure so many things but we are somehow not there yet.

Are there still laws in place that prohibit research using stem cells? That might not help

The reason that whole controversy basically evaporated is that embryonic stem cells have so far been useless - anything you can do with them can also be done with adult stem cells.

As far as I know there is no treatment, or even research that requires those cells vs adult ones. It also helps that there are embryonic cell lines available commercially, with no restrictions (in the US), for those who want to specifically study them and not adult ones.

So to answer your question: No, the laws are not harming anything.

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