Sphinx and reStructuredText are, IMHO, underrated power houses of document building. With extensions, you can hook them up to Zotero (or whatever)-managed bibtex files. You can render to beautiful HTML files, and you get latex PDFs and epubs for free. First class latex-math support, plenty of integrations with things like mermaid, graphviz, and the ability to build super-powerful custom directives to do basically any…
I guess latex is still unbeatable for writing complex math expressions. These days, when I don't need that, I'm happy with AsciiDoc.
Typst is better IMO