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Edit: link to my previous comment with a list of papers from the last time a similar thread was posted for those interested. https://news.ycombinator.com/item?id=37018392 This was a busy summer for developmental biology, full disclosure that I am an author on one of these papers and my thesis work is in embryo models/early development. The Hanna group was unfortunately scooped by some unethical behavior but their mod…
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Edit: link to my previous comment with a list of papers from the last time a similar thread was posted for those interested. https://news.ycombinator.com/item?id=37018392 This was a busy summer for developmental biology, full disclosure that I am an author on one of these papers and my thesis work is in embryo models/early development. The Hanna group was unfortunately scooped by some unethical behavior but their mod…
Earlier quoted context omitted.
It’s a model because it’s not completely equivalent. Medicine has learned a great deal from studying rodents, but humans are quite different. For one thing human embryos would have already been implanted in a womb for a week at that point and a great deal of signaling occurs between embryo and the uterus.
>"For one thing human embryos would have already been implanted in a womb for a week at that point" At what point? Implantation typically occurs 6-12 days after fertilization. This experiment starts at the equivalent of day 7. IVF is a thing. It sounds like you're just guessing. Edited to add, this article says "It would be illegal to implant them into a patient’s womb" which is a far cry from what you are implying,…
“This stage corresponds to day 7 of the natural human embryo, around the time it implants itself in the womb.”
“The researchers discovered that if the embryo is not enveloped by placenta-forming cells in the right manner at day 3 of the protocol (corresponding to day 10 in natural embryonic development), its internal structures, such as the yolk sac, fail to properly develop.”
“The stem cell–based embryo-like structures (termed SEMs) developed normally outside the womb for 8 days, reaching a developmental stage equivalent to day 14 in human embryonic development.” (So ~1 week post implantation for a human embryo.)
Edit: link to my previous comment with a list of papers from the last time a similar thread was posted for those interested. https://news.ycombinator.com/item?id=37018392 This was a busy summer for developmental biology, full disclosure that I am an author on one of these papers and my thesis work is in embryo models/early development. The Hanna group was unfortunately scooped by some unethical behavior but their mod…
https://hn.algolia.com/?dateRange=all&page=0&prefix=true&que...
Edit: link to my previous comment with a list of papers from the last time a similar thread was posted for those interested. https://news.ycombinator.com/item?id=37018392 This was a busy summer for developmental biology, full disclosure that I am an author on one of these papers and my thesis work is in embryo models/early development. The Hanna group was unfortunately scooped by some unethical behavior but their mod…
Would you be open to giving a talk on the topic?
"we are summoning things that cannot be easily unsummoned"
Reducing human suffering is a noble goal and infertile couples could benefit from this research. I would rather have western world make giant leaps in this field and also set the direction of ethics here rather than just banning it and leaving it up to Russia and China to conduct this sort of research in their secret facilities.
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