The attack surface of yubikey vs a laptop you carry around is interesting. Nobody seems to reflect that if you physically steal the laptop, guess what, the usb key that's still in there was also stolen. Anybody using USB locks? If you are focussing on FIDO for password management, I am assuming you are protected against HID emulating devices, like a rubberducky or teensy flashed with some malware installing HID emula…
I think that largely misses the point of having such a key. I have one, and I'm well aware that if my laptop is stolen, so is that key. But the point of it is not to protect the laptop from the outside; that's why my drive is encrypted.
The point of that particular Yubikey is to secure passwords and authenticate to some websites, all of which requires either a PIN or more passwords, even after breaking the encryption of the drive itself.
Then there's the fact that, if you steal my laptop, you're probably looking to sell it for cash. That is to say, threat models matter. If your a journalist in a hostile country, maybe other steps should be taken. But most of us here on a site called Hacker News aren't under such threats, romantic as they may be.