I guess it depends if your website does something valuable or substantial. If it's just your hobby site... great, develop it without JS. But if it's a site people pay to access (or requires ads) and they expect some functionality - like Youtube or Netflix say - I don't think this is possible.
I’m genuinely curious: why would Netflix or YouTube not work without JS? As far as I understand it, YouTube and Netflix are a nicer UX with JS but there’s no particular feature that would kill it completely. Like, for example, I thought that you can play HLS* manifests from plain HTML5 video tags. EDIT: I was thinking of HLS and not DASH
But HLS has wide support on mobile browsers, and on desktop Safari. (Source: https://caniuse.com/http-live-streaming.) So YouTube should in theory be able to support JavaScript-free playback for many of its users.