Is that they are your bodies away of wrapping up something bad that it can't otherwise deal with. In a protective layer to contain. Similar to how a clams makes a pearl layer by layer around a foreign particle.
Scientists are finding fungi in cancerous tumors
41–50 of 67 posts
Re: Scientists are finding fungi in cancerous tumors
#42Earlier quoted context omitted.
Lycan is also an assemblage of fungi and cyanobacteria or algae if I'm not mistaken..
Lichen are. (Lycan are werewolves I think.)
Re: Scientists are finding fungi in cancerous tumors
#43Re: Scientists are finding fungi in cancerous tumors
#44Anytime you perform a sequencing experiment you will get _some_ microbial/fungal contamination. Every time. You can even check this yourself today. Analyse any publicly available (unprocessed) whole genome sequencing data. Usually the contamination is This study hasn’t ruled out contamination as the cause for the results. Given that, it’s very likely to be BS.
Can you provide a source for this? There are a lot of cranks right now claiming that there's no such thing as a virus because we've never been able to get a non-contaminated sequence (something I've assumed was due to culturing). If this is true of everything there's no limit to what can and cannot exist per their insane arguments.
Re: Scientists are finding fungi in cancerous tumors
#45Anytime you perform a sequencing experiment you will get _some_ microbial/fungal contamination. Every time. You can even check this yourself today. Analyse any publicly available (unprocessed) whole genome sequencing data. Usually the contamination is This study hasn’t ruled out contamination as the cause for the results. Given that, it’s very likely to be BS.
This is newsworthy because the Swedish healthcare system recently discovered that prostate cancer patients who took oral Terbinafine to treat toenail fungus had much better cancer outcomes. The same holds for Terbinafine and colon cancer. We are currently in the WTF is going on here phase. $5 of anti-fungal medication cuts some cancer death rates in half? Is a tiny amount of fungus in cancer tissue driving growth and…
Re: Scientists are finding fungi in cancerous tumors
#46Earlier quoted context omitted.
> You can even check this yourself today. As much as I would love to be able to do this, I’m unsure where to start, and while I’m certain there would be a stackoverflow community for it, I wouldn’t even know what to ask. I know this sounds like a joke comment, but I feel like we live in a time where someone could post some Jupyter notebooks on the matter, and for someone to create a step by step video on YouTube to g…
Start with downloading SRA toolkit: https://github.com/ncbi/sra-tools/wiki/02.-Installing-SRA-To... Find some data of interest: https://www.ncbi.nlm.nih.gov/sra?term=(%22Homo%20sapiens%22[... (This searches SRA for human genome sequences on illumina with fastq files available) Run fasterq-dump on the SRR (listed as "Runs" in the SRA page of your choice): fasterq-dump SRR21812682 Download a microbial genome of interes…
Yes, this is an approximate workflow. It doesn’t take that much specialized knowledge to get it running.
However step 2/3 (find/download a dataset of interest) is harder. Finding whole genome sequencing data for a cancer that you can download without being part of a research institution is difficult. There are a lot of controls over who can access raw DNA sequences from patients. RNA data are much more readily available as they are less identifiable.
Specifically, here is the type of access you need:
https://gdc.cancer.gov/access-data/obtaining-access-controll...
The reasons for this are good and I’m not trying to say otherwise. Just that from a practical perspective, being able to technically perform the analysis is doable for many non-biomedical people here. However, accessing the raw data is much more difficult.
Re: Scientists are finding fungi in cancerous tumors
#47Anytime you perform a sequencing experiment you will get _some_ microbial/fungal contamination. Every time. You can even check this yourself today. Analyse any publicly available (unprocessed) whole genome sequencing data. Usually the contamination is This study hasn’t ruled out contamination as the cause for the results. Given that, it’s very likely to be BS.
> You can even check this yourself today. As much as I would love to be able to do this, I’m unsure where to start, and while I’m certain there would be a stackoverflow community for it, I wouldn’t even know what to ask. I know this sounds like a joke comment, but I feel like we live in a time where someone could post some Jupyter notebooks on the matter, and for someone to create a step by step video on YouTube to g…
If you had thousands of sequence reads from multiple unknown organisms, then you’d have to implement a meta genomics pipeline.
All the software for this is already made. You take your sequence reads, trim them a bit, assemble them into “contigs”, and then map those contigs to known genomes in the magical tree of life.
Re: Scientists are finding fungi in cancerous tumors
#48I really hope these sorts of things make their way to trials soon. recently found out that I have a recurrance of colon cancer...
Re: Scientists are finding fungi in cancerous tumors
#49Great./s Now the people who told me that drinking baking soda in water would cure my cancer "because cancer is a fungus" are going to go wild over this.
You might be laughing, but baking soda used to be injected to tumors to reduce lactic acidosis (cancer cells can't proliferate without being immersed in lactic acid). So the people you mentioned might have been running on older research and scientific beliefs. The new version is to use medication that actually decreases lactic acid to slow down/stop growth of tumors (DCA, mega-dose thiamine etc.) Another funny fact -…
Re: Scientists are finding fungi in cancerous tumors
#50Earlier quoted context omitted.
This is newsworthy because the Swedish healthcare system recently discovered that prostate cancer patients who took oral Terbinafine to treat toenail fungus had much better cancer outcomes. The same holds for Terbinafine and colon cancer. We are currently in the WTF is going on here phase. $5 of anti-fungal medication cuts some cancer death rates in half? Is a tiny amount of fungus in cancer tissue driving growth and…
Thanks for giving me my reading material this week, as someone with stage 4 colon cancer :) I also read about promising outcomes with fenbendazole (dog deworming medicine) and colon/lung cancer, hope these finally unlock the fix for metastasis.