Remote startups with what cheap money? That era is coming to an end. They won't win anything, with cheap or expensive labor.
The startup boom exists because money was so cheap you had to spend it. Then consumer spending started to ramp up again and money was flowing both ways. Worrying about profits was viewed as silly since that would get in the way of maximizing growth under the assumption that you could one day flip a switch and generate profit.
With inflation rising consumers have much less to spend (and are already starting to rapidly take on more debt), this alone would hurt tech companies (you see this in cancelation rates rising with streaming services and a drop in e-commerce spending), but the end of cheap money will have disastrous consequences for the startup ecosytem.
The number of IPOs is declining rapidly. Investors saw this coming when the pandemic hit and started to get everything together so the could cash out their chips before the casino closed.
Massive layoffs are coming in tech as unprofitable companies will be forced to demonstrate that they can in fact make money (if they really can) and even profitable companies start to see their income drop (since their income is primarily other tech companies or consumers who will be increasingly tightening their wallets).
What's coming is going to make the dotcom bust seem mild.