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Fasting boosts stem cells’ regenerative capacity (2018)

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Re: Fasting boosts stem cells’ regenerative capacity (2018)

#41

One more reason to become Muslim.

Religious fasting has little to do with the therapeutic ones. For a start, they are too short and are not even 24h. Second, the idea is usually to binge on cakes everyday at sunset.

The old Lenten Black Fast [1] probably applies.

- One meal a day

- No meat, lacticinia, or alcohol allowed in the meal

- Water allowed throughout the day

[1] https://en.wikipedia.org/wiki/Black_Fast

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#42
post #39

Earlier quoted context omitted.

Wait what? English is not my native language, are you saying you didn't eat any food for 30 consecutive days??

60 days as I understood - first 30 days just water and then the next 30 days water with electrolytes

This guy should be dead, his body should have digested himself. How can someone not eat anything by his own will for more than a few days ? (5-7 max) you should pass out. Also in the case that were true, let me be clear: No food intake for multiple days is extremely dangerous for your health, it will upregulate autophagy, apoptosis and will break your mitochondria bioenegetics which will explode your oxidative stress (and therefore DNA breaks) and will induce partial ischemia/hypoxia/hypoglycemia which leads to an accelerated ageing process. Autophagy is nice, in little dose, and is best emulated pharmacologically (e.g. via some polyphenols)

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#44

One more reason to become Muslim.

Imagine not being able to single out fasting and doing it without getting yourself into a religion. What other things can you not single out and need to delegate the thinking to religion for I wonder?

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#45
post #28

Earlier quoted context omitted.

I did a 7 day fast, and I mostly ended up losing fat. While I did not do any scientific measurement, i was able to exercise the same post the 7 day fast and my belly fat came down big time. Maybe body builders lose lean body mass when they fast, but it does not seem to hold true for the average human.

You have mostly lost water to be precise. As well as muscle. You need an expensive Dual-energy X-ray absorptiometry scan in order to precisely tell the body mass composition.

How would you know, without the "expensive" densitometry scan?

My anecdotal experience: I lost weight via alternate day fasting and did indeed shell out the 120 euro that two scans cost me. I lost mainly fat, my lean body mass after 6 months was down 4 pct, within error range I'd assume. I worked out normally through the entire period and even did things like a 200km bike trip during a 72hr fast. (I did a few of those to compensate for not fasting on holidays). Great experience, never felt better tbh.

One thing I think I learned was the exact threshold of power that allowed me to keep burning fat. Its hard to describe the feeling but after doing this for months (over a year by now) I think I know exactly when I can still push and continue on fat, and when I need to slow down to prevent lbm loss. Doing sprints, short intervals etc. would likely cause me to break proteins in the body and indeed be counterproductive - but here more research is probably needed, and individuals will likely have different thresholds.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#46

Earlier quoted context omitted.

I did water only for the first 30 days, which was stupid, and then supplemented electrolytes -- mainly Sodium, Magnesium, Potassium -- from days 31 onward. That one was super strict, no coffee, no tea, nothing. EDIT - Also, this is _not_ how I would go about this now 5+ years later with more experience under my belt.

Wait what? English is not my native language, are you saying you didn't eat any food for 30 consecutive days??

60 consecutive days

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#47
post #39

Earlier quoted context omitted.

60 days as I understood - first 30 days just water and then the next 30 days water with electrolytes

This guy should be dead, his body should have digested himself. How can someone not eat anything by his own will for more than a few days ? (5-7 max) you should pass out. Also in the case that were true, let me be clear: No food intake for multiple days is extremely dangerous for your health, it will upregulate autophagy, apoptosis and will break your mitochondria bioenegetics which will explode your oxidative stress…

I guess he ate some bugs in his sleep.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#48
post #39

Earlier quoted context omitted.

60 days as I understood - first 30 days just water and then the next 30 days water with electrolytes

This guy should be dead, his body should have digested himself. How can someone not eat anything by his own will for more than a few days ? (5-7 max) you should pass out. Also in the case that were true, let me be clear: No food intake for multiple days is extremely dangerous for your health, it will upregulate autophagy, apoptosis and will break your mitochondria bioenegetics which will explode your oxidative stress…

Not sure why I’d pass out from just not eating, I had plenty of body fat on me for the entirety of the fast. I wasn’t starving myself.

Estimating by weight loss my metabolism was still burning well over 2500kcal daily at the end of the fast.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#49
post #12
post #3

Fasting is also good to pocket and limits exposure to unhealthy food.

And good for getting rid of lean body mass...

Completely incorrect.

Time-restricted eating and concurrent exercise training reduces fat mass and increases lean mass in overweight and obese adults

https://pubmed.ncbi.nlm.nih.gov/34042299/

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#50
post #39

Earlier quoted context omitted.

60 days as I understood - first 30 days just water and then the next 30 days water with electrolytes

This guy should be dead, his body should have digested himself. How can someone not eat anything by his own will for more than a few days ? (5-7 max) you should pass out. Also in the case that were true, let me be clear: No food intake for multiple days is extremely dangerous for your health, it will upregulate autophagy, apoptosis and will break your mitochondria bioenegetics which will explode your oxidative stress…

That's not how it works at all. Not drinking water will damage/kill you real fast, not eating food on the other hand is pretty safe for most people. The longest fast was ~380 days [0]

If you have some fat (75% of westerners are heavily overweight or obese) you can easily fast on water only for weeks, of course you're not going to be able to exercise heavily every day or run a marathon. But if you're an overweight office worker with no other health issues you'll be just fine.

For anything over a week you probably should get medical assistance to keep an eye on vitamins and electrolytes, but you're not going to drop dead/unconscious/destroy your DNA

What's dangerous is starvation, aka fasting until your body starts giving up, but for the average westerner that's going to take a long time.

[0] https://en.wikipedia.org/wiki/Angus_Barbieri%27s_fast

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