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Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

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Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#41

Post by easymodex »

JohnJamesRambo wrote: post #5

I think I’m going to start taking aspirin. Oddly enough I took that a few times because I didn’t have ibuprofen and I do feel like it helped a lot with the weird long symptoms I am experiencing. I’m triple vaccinated before anyone asks. I haven’t tested positive for Covid on rapid tests but a lot of people seem to be in the boat I’m in right now.

I just got the booster shot today, previous times I had a weird headache and a new vein (felt it pulsing, didn't have it before) popped up in the white part of my eye (it's still there after 6 months), second time I had minor heart palpitations the day after so I'm kinda worried this time. Would taking Aspirin help prevent any kind of weirdness like that? I need to know asap so I can take it before anything potentially starts happening.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#42

Post by sva_ »

runnerup wrote: post #8
nicoburns wrote: post #4

Huh. This is interesting. I also have some fatigue, but my most obvious long-covid symptom is heart pain/strain which is aggravated by either an elevated heart rate or dehydration. I'm no expert, but intuitively this would seem to provide a good explanation of those symptoms.

I'm hopeful that research into whatever "long covid" syndrome is/isn't leads to excellent new medical knowledge that applies to much more than just COVID edge-cases. I suddenly got similar symptoms since getting a nasty version of strep throat last October. Notably I had an elevated fever (>102F) for quite a few days straight. I've never had COVID but I did get the mRNA vaccines + booster. Since that fever, my heart…

Are you sure it's caused by COVID, or perhaps ever since you were sick you were exercising less?

I had similar symptoms to what you describe after just not being very active for quite a while, but it resolved after I did regular cardio (cycling) for a while and ate better.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#44

Post by wantsanagent »

This is a big hammer. Please note this section:

"A proton pump inhibitor (PPI) pantoprazole 40 mg/day was also prescribed for gastric protection. Such a regime must only be followed under strict and qualified medical guidance to obviate any dangers, especially haemorrhagic bleeding, and of the therapy as a whole."

Induced hemophilia is no joke.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#45

Post by lrem »

JohnJamesRambo wrote: post #36
andor wrote: post #29

Earlier quoted context omitted.

I assume you have read the hint that the authors left in the introduction for people like you: "Such a regime must only be followed under strict and qualified medical guidance to obviate any dangers, especially haemorrhagic bleeding, and of the therapy as a whole."

Well yes I’m doing a very light version of the protocol, no industrial strength anticoagulants. :)

So likely you won't meet the "better than placebo" threshold.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#46

Post by frostwarrior »

easymodex wrote: post #41
JohnJamesRambo wrote: post #5

I think I’m going to start taking aspirin. Oddly enough I took that a few times because I didn’t have ibuprofen and I do feel like it helped a lot with the weird long symptoms I am experiencing. I’m triple vaccinated before anyone asks. I haven’t tested positive for Covid on rapid tests but a lot of people seem to be in the boat I’m in right now.

I just got the booster shot today, previous times I had a weird headache and a new vein (felt it pulsing, didn't have it before) popped up in the white part of my eye (it's still there after 6 months), second time I had minor heart palpitations the day after so I'm kinda worried this time. Would taking Aspirin help prevent any kind of weirdness like that? I need to know asap so I can take it before anything potential…

Vaccines are not Covid.

Even the inactivated virus ones. They're just a very small viral load with an adjuvant to enhance immune response.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#47

Post by nick__m »

lrem wrote: post #45
JohnJamesRambo wrote: post #36

Earlier quoted context omitted.

Well yes I’m doing a very light version of the protocol, no industrial strength anticoagulants. :)

So likely you won't meet the "better than placebo" threshold.

A placebo is frequently better than nothing and sometimes better than the real thing. I can even work if you know that it's a placebo !

Also placebo are getting stronger https://drdavidhamilton.com/the-placebo-effect-is-getting-st... ;)

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#49

Post by Jabbles »

phkahler wrote: post #27
deelowe wrote: post #16

Earlier quoted context omitted.

It feels to me that the medical community at large looks almost exclusively at data regarding severe cases. I'm certainly no medical expert but it seems reasonable to me that the treatments for someone who is literally dying from COVID could be completely orthogonal from those who are in the early stages of the infection. My understanding of severe cases is that the body is no longer or not only fighting the virus bu…

>> It feels to me that the medical community at large looks almost exclusively at data regarding severe cases. I'm certainly no medical expert but it seems reasonable to me that the treatments for someone who is literally dying from COVID could be completely orthogonal from those who are in the early stages of the infection. This seems to be a problem with every account of "treatment X doesn't work". They wait until…

Obviously the medical community is aware of this.

Take for example the very recent approval of Molnupiravir:

https://www.bbc.co.uk/news/health-59163899

https://www.nejm.org/doi/full/10.1056/NEJMoa2116044

We conducted a phase 3, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of treatment with molnupiravir started within 5 days after the onset of signs or symptoms in nonhospitalized, unvaccinated adults with mild-to-moderate, laboratory-confirmed Covid-19 and at least one risk factor for severe Covid-19 illness.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#50

Post by myoldohiohome »

jokethrowaway wrote: post #37

Sounds exactly like chronic fatigue syndrome, I don't know why we keep calling it Long COVID while we have a name for it. https://www.nhs.uk/conditions/chronic-fatigue-syndrome-cfs/ > Suggested causes or triggers for ME/CFS include: > viral infections, such as glandular fever > bacterial infections, such as pneumonia > problems with the immune system > a hormone imbalance > your genes – ME/CFS seems to be more common…

I hope so too. I recognized the symptoms (in myself) as soon as I started reading the abstract.

---

from the link cdrini posted above, which is a Guardian article by one of the authors of the study in the original post.[0]

"Even those without long Covid could benefit from such research, as symptoms noted in long Covid patients show many similarities to those seen in chronic and viral-related illnesses including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) – another disease that has been dismissed as “psychological” for decades. Just because we have not yet identified a biomarker for long Covid does not mean biomarkers do not exist. We just need to look harder."

[0] https://news.ycombinator.com/item?id=29808020

PS. Hope the post is done correctly, it's my first one here.

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