My condolences to anyone who's lost a friend or relative to addiction - thanks to the human vultures who reap the rewards. It's possible that by vigorously pursuing and prosecuting the people who can afford to purchase and disseminate hard narcotics - instead of the users and a pusher or two - most of the problem would dry up. I'm not optimistic about that happening. The little guys are easier to catch, and caps are…
That said, the opioid crisis in the USA has been largerly fueled by prescription drugs. If by little guys you mean doctors, and big guys you mean the manufacturers;well there's been some progress on that. But obviously and certainly not enough.
Let's also not overlook the convenient blind eye of regularors (read: government).