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Nobel Prize in Physiology or Medicine 2021

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Re: Nobel Prize in Physiology or Medicine 2021

#41

Post by bacro »

refurb wrote: post #26
siva7 wrote: post #3

I would have appreciated this year's one going for mRNA vaccine research as this would have been clearly the one to meet Nobel's will.

It's not a popularity content. Nobel prizes are typically not given until several years after the work is complete and enough time has passed to fully appreciate the significance of it. I'd say it's a bit early for mRNA vaccines.

Funnily enough, Egas Moniz was given the nobel prize in medicine for the lobotomy procedure. He claimed it helped the mentally ill. How scientific was that? XD

Re: Nobel Prize in Physiology or Medicine 2021

#42

Post by kibwen »

thecopy wrote: post #38
pibechorro wrote: post #33

Earlier quoted context omitted.

They can just take the nobel they censored from ivermectin and attribute it to the mrna shots, no? /S

Who are they and how did they censor?

The parent is sarcastically suggesting that there is a conspiracy to suppress ivermectin for use in treating covid. Ivermectin won the 2015 Nobel for its use in treating roundworm parasites. (Just to be maximally clear, covid is a virus, not a parasite.)

Re: Nobel Prize in Physiology or Medicine 2021

#43

Post by silvester23 »

bacro wrote: post #40
Cthulhu_ wrote: post #29

Earlier quoted context omitted.

On the one side, you are correct and it's only last year / this year that mRNA vaccines have seen widespread adoption. On the other, mRNA research goes back to the 80's, and mRNA vaccine research goes back twenty years; these facts are often overlooked by the "it was developed too fast" crowds. That said, > It's not a popularity content. And yet, they gave Obama the Nobel Peace Prize the year he was elected, without…

>On the other, mRNA research goes back to the 80's, and mRNA vaccine research goes back twenty years; these facts are often overlooked by the "it was developed too fast" crowds. I am on that camp, that it was developed too fast and I do not think people should be mistreated because they think that. After all, there has been some adverse effects for some of the people who took it (like the auto-immune disease for the…

What I fail to understand is how you seem to think that you can can assess the risks associated with contracting the virus better than the risks associated with getting the vaccine.

At this point, so many more people have received the vaccine than have contracted the virus that I think it's fairly safe to say that we know much more about how people react to the vaccine than the virus (which also keeps mutating unlike the vaccine).

It's true that we don't know the long-term effects of the vaccine but

1) my understanding is that medically speaking, a few weeks after the shot every trace of the actual vaccine is gone from the body and all that remains is that your immune system has learned how to fight the virus and

2) we certainly do not know the long-term effects of the virus either

So unless you are in a position where you can completely seal yourself off and be sure you will not get the virus, it's a choice between getting vaccinated and getting the virus. Considering what I wrote above, to me that is an obvious choice.

Re: Nobel Prize in Physiology or Medicine 2021

#44

Post by bacro »

causi wrote: post #19
ACS_Solver wrote: post #16

Earlier quoted context omitted.

That's what I was hoping to see, an award to Karikó and Weissman for their mRNA research. I'm sure they'll get the Nobel within the next few years, but it would have been appropriate to award it now. The Nobel Committee doesn't rush the prizes, and they don't generally go to new research, but mRNA would be a very justified exception. We're currently in the worst pandemic in a century, and over the last ten months we'…

I have to say, awarding it for mRNA research could easily save lives by turning a few of the vaccine-hesitant.

As I said in another comment, Egas Moniz won the Nobel prize in medicine for the lobotomy procedure for mentally-ill people!!

Re: Nobel Prize in Physiology or Medicine 2021

#45

Post by xattt »

bacro wrote: post #40
Cthulhu_ wrote: post #29

Earlier quoted context omitted.

On the one side, you are correct and it's only last year / this year that mRNA vaccines have seen widespread adoption. On the other, mRNA research goes back to the 80's, and mRNA vaccine research goes back twenty years; these facts are often overlooked by the "it was developed too fast" crowds. That said, > It's not a popularity content. And yet, they gave Obama the Nobel Peace Prize the year he was elected, without…

>On the other, mRNA research goes back to the 80's, and mRNA vaccine research goes back twenty years; these facts are often overlooked by the "it was developed too fast" crowds. I am on that camp, that it was developed too fast and I do not think people should be mistreated because they think that. After all, there has been some adverse effects for some of the people who took it (like the auto-immune disease for the…

You may be conflating the mRNA vaccine with viral vector ones.

Re: Nobel Prize in Physiology or Medicine 2021

#46

Post by satisfice »

siva7 wrote: post #3

I would have appreciated this year's one going for mRNA vaccine research as this would have been clearly the one to meet Nobel's will.

I can only assume they are waiting until next year to be sure how the vaccine picture shakes out. MRNA vaccines are clearly safe and effective, and have saved countless lives, but with the dopey politics in Sweden about Covid, I am not really that surprised.

Re: Nobel Prize in Physiology or Medicine 2021

#47

Post by ramraj07 »

docdocgoose wrote: post #17

I appreciate that some Nobel selections, like this one, are for core biological discoveries rather than hot topics. How our bodies perceive / interface with the world is fundamental to our human experience: Pain, temperature, positioning. And that these perceptions can be significantly modulated by how our bodies process them (eg pain). Not only is their actual body of work impressive, as it cuts across so many metho…

Hard disagree. These are for lack of better word standard discoveries that the high intensity labs discover with pretty much standard methodologies and no Innovations worthy of a Nobel. Of course we have receptors for heat and touch, and of course someone eventually found them. What’s original in that process? This is not RNAi, or CRISPR, or GFP. One of the more underwhelming Nobels in recent times. Somehow worse than superresolution.

Re: Nobel Prize in Physiology or Medicine 2021

#48

Post by ramraj07 »

refurb wrote: post #26
siva7 wrote: post #3

I would have appreciated this year's one going for mRNA vaccine research as this would have been clearly the one to meet Nobel's will.

It's not a popularity content. Nobel prizes are typically not given until several years after the work is complete and enough time has passed to fully appreciate the significance of it. I'd say it's a bit early for mRNA vaccines.

What exactly have this years Nobel research been significant for? Like in real terms?

Re: Nobel Prize in Physiology or Medicine 2021

#49

Post by refurb »

Tomte wrote: post #34
refurb wrote: post #26

Earlier quoted context omitted.

It's not a popularity content. Nobel prizes are typically not given until several years after the work is complete and enough time has passed to fully appreciate the significance of it. I'd say it's a bit early for mRNA vaccines.

That's the current practice, but siva7 is right in regards to timing and Nobel's will: "to be distributed annually as prizes to those who, during the preceding year, have conferred the greatest benefit to humankind." ( https://www.nobelprize.org/alfred-nobel/full-text-of-alfred-... )

If you look back it’s usually a decade or more before a discovery gets a Nobel prize. Which makes sense, since it’s relevance isn’t usually immediately apparent.

Re: Nobel Prize in Physiology or Medicine 2021

#50

Post by dav_Oz »

Before it gets hijacked by zealots on both side in saving or depopulating the planet. It was a quite conservative pick given the complexities and interwovenness of discoveries in a given field: Citation Index and some fundamental property (TRPV --> Temperature/Heat/Pain & PIEZO--> Touch/Proprioception), it was relatively easy to pinpoint those two (no pun intended).

The mRNA technology would not be so clear cut in terms of persons involved since it had to go through many hurdles. There are two illustrative roadmaps [1][2] (And yes, Malone et al. was a early contributor as well (1989)[3])

[1]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554980/bin/ijm... [2]https://media.springernature.com/full/springer-static/image/... [3]https://www.pnas.org/content/86/16/6077

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