I just started testing glucose this last week, for health and training purposes. Of course, it just started to get cold in the mornings, and I wake early, so I’m dehydrated, cold and stiff. It takes a bit of water drinking and bodyweight-squatting and arm rubbing to get vigorous circulation for a good drop of blood. I haven’t figured out how to store and dispose of the lances yet, and the bother of it all makes me very sympathetic to those who aren’t doing it for fun and gains.
Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
41–50 of 86 posts
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#42The device claims to have 97% of reading within 15% of the Freestyle Libre, which itself is then not as accurate as blood glucose. Put another way, it’s less accurate than a device that’s already less accurate than finger sticks. Given this info, I’m not sure this version is practically useful yet in terms of accuracy.
Hi, this is actually my field of expertise! IdealMedTech is a clinical glucose control startup targeting inpatient glucose control. Having an MARD (mean absolute relative difference, or in math terms, E[|g-r|/r], g is measured glucose, r is reference glucose) of below 15% is actually considered very good for glucose monitoring. We did a study that involved modelling different levels of sensor error, and you actually…
> Most sensors on the market that are considered best in class (eg Dexcom G6) have guaranteed MARD
Disclaimer: I work for Dexcom.
A few times every year, there's a ton of hype about some new noninvasive device, and the newbies get a bit worried, but the old timers just shrug it off.
We (humanity) will literally be able to regrow new pancreases with stem cells before we have accurate noninvasive blood glucose devices. Even Tim Cook with unlimited resources at his disposal admitted it's a much harder than they thought.
That said, I think there's a large market for people without diabetes who are interested in their blood glucose and who may not need super-accurate readings. For example, as a long distance runner, it'd be super helpful to know if my blood sugar is trending down before I bottom out, so I can know when to eat a gel pack, etc. It would also be useful for people trying to lose weight to learn how their eating habits and exercise affect their blood sugar levels.
Noninvasive devices may be better for this group of people who don't need the devices to be accurate enough to make decisions about insulin-dosing.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#43I just started testing glucose this last week, for health and training purposes. Of course, it just started to get cold in the mornings, and I wake early, so I’m dehydrated, cold and stiff. It takes a bit of water drinking and bodyweight-squatting and arm rubbing to get vigorous circulation for a good drop of blood. I haven’t figured out how to store and dispose of the lances yet, and the bother of it all makes me ve…
For disposing of lances - if you're in San Francisco at least, Walgreens provide a free sharps disposal service. They provide a sharps container at no cost, and will take in your full (used) sharps containers.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#44Earlier quoted context omitted.
I worked on the Freestyle Libre, I’m thrilled to hear it’s at least a workable solution for you. When I was working at Abbott, I often volunteered for testing finger-stick devices, which made me appreciate a small part of what people with diabetes have to endure.
I've used them and they're great just pricey
I use a Freestyle Libre sensor and I like it better than finger sticks. When I was doing finger sticks I was averaging 4 tests a day; before each meal and at bedtime. With the Freestyle Libre I'm checking my glucose an average of 20 times a day. But the Freestyle Libre sensors are quite expensive. I have insurance so my out of pocket expenses are very low, but my provider bills $1074 for 2 sensors, which last for 4 weeks.
I have read comments from other posts that buyers without insurance can get sensors for substantially less, but they are still quite expensive. When I was doing finger sticks I could get enough test strips for a month for about $30.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#45The device claims to have 97% of reading within 15% of the Freestyle Libre, which itself is then not as accurate as blood glucose. Put another way, it’s less accurate than a device that’s already less accurate than finger sticks. Given this info, I’m not sure this version is practically useful yet in terms of accuracy.
Hi, this is actually my field of expertise! IdealMedTech is a clinical glucose control startup targeting inpatient glucose control. Having an MARD (mean absolute relative difference, or in math terms, E[|g-r|/r], g is measured glucose, r is reference glucose) of below 15% is actually considered very good for glucose monitoring. We did a study that involved modelling different levels of sensor error, and you actually…
This... brought back some memory...to average or not to average... C8 Medisensors achieved better weekly MARD in the early 201*. But the problem was, on a bad day, no one knows why it was bad..., so no way to alert the user (unless the reading was way off). Even though on "average", performance looks nice, but a bad day the data can be very problematic for a user, and the user has not way to trust the device based on MARD...
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#46Earlier quoted context omitted.
so what foods did you cut out, and what foods do you regularly eat?
Everybody's body responds differently, so you have to experiment to see what works for you. The CGM has been a great tool for that. I also use a Keto-Mojo for blood glucose and ketone testing now and then. What's worked for me is a diet of eggs, cheese, bacon, chicken, ground beef, ground pork, roast beef, turkey, pepperoni, kale, cabbage, Brussels sprouts, coffee, seltzer, bone broth, half & half, heavy cream, rebel…
Wow - thought I'd never find anyone else with my diet on HN, but (other than half & half, ice cream and Brussels sprouts), we're surprisingly close. I'd also add a few things, such as almond milk, homemade mayo, flax, cocoa powder, 100% cocoa squares, and head lettuce for burger wraps, but that's about it. Like you, I tried things like carbalose flour and erythritol with bad results, but stevia powder seems ok. I'm glucose intolerant but thin and would likely need some sort of drug if I wasn't eating this way - which I have been since 2008.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#47Earlier quoted context omitted.
Hi, this is actually my field of expertise! IdealMedTech is a clinical glucose control startup targeting inpatient glucose control. Having an MARD (mean absolute relative difference, or in math terms, E[|g-r|/r], g is measured glucose, r is reference glucose) of below 15% is actually considered very good for glucose monitoring. We did a study that involved modelling different levels of sensor error, and you actually…
This... brought back some memory...to average or not to average... C8 Medisensors achieved better weekly MARD in the early 201*. But the problem was, on a bad day, no one knows why it was bad..., so no way to alert the user (unless the reading was way off). Even though on "average", performance looks nice, but a bad day the data can be very problematic for a user, and the user has not way to trust the device based on…
This is a great point, and precisely why we're using two sensors and a simple voting algorithm in our first in man trial (3+ sensors and associated algorithms were deemed too risky by FDA for initial studies).
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#48I find some of the this vague in this announcement. Non invasive BGM is the "holy grail" in this field. Tons of companies have failed after big investments. Some scammers are out there they claim since decades they solved the problem. I would be curious about peer reviewed publications of their technology.
A friend of mine is working on this too. Close to market. He is the only one that regularly published peer reviewed publications on this topic.
In fact, I remember I have written an SBIR grant proposal on the technology that was evaluated by an idiot who googled one of the components, realized a single unit (as compared to 10000 units) would cost 50 grant and rejected it based on the claim that the technology would be too expensive in practice. I had written in the proposal that, produced in quantities, the cost of this item is in the mid 3 dollar digits per unit. An idiot and google are a very dangerous combination, even at the NIH.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#49Earlier quoted context omitted.
Hi, this is actually my field of expertise! IdealMedTech is a clinical glucose control startup targeting inpatient glucose control. Having an MARD (mean absolute relative difference, or in math terms, E[|g-r|/r], g is measured glucose, r is reference glucose) of below 15% is actually considered very good for glucose monitoring. We did a study that involved modelling different levels of sensor error, and you actually…
> Most sensors on the market that are considered best in class (eg Dexcom G6) have guaranteed MARD Disclaimer: I work for Dexcom. A few times every year, there's a ton of hype about some new noninvasive device, and the newbies get a bit worried, but the old timers just shrug it off. We (humanity) will literally be able to regrow new pancreases with stem cells before we have accurate noninvasive blood glucose devices.…
"A few times every year, there's a ton of hype about some new noninvasive device, and the newbies get a bit worried, but the old timers just shrug it off"
This.
But a buddy of mine may surprise you soon. And I worked in the field too.
Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors
#50non-invasive. Any investors here? I could offer non-invasive blood pressure monitoring (no, not based on pulse wave velocity).