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Effect size is significantly more important than statistical significance

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Re: Effect size is significantly more important than statistical significance

#41
post #38

Earlier quoted context omitted.

Come into Bayesian land, the water is fine. The whole NHST edifice starts to seem really shaky once you stop and wonder if "True" and "False" are really the only two possible states of a scientific hypothesis. Andrew Gelman has written about this in many places, e.g. http://www.stat.columbia.edu/~gelman/research/published/aban... .

Bayesian reasoning has even worse underpinnings. You don’t actually know any of the things the equations want. For example suppose a robot is counting Red and Blue balls from a bin, the count is 400Red and 637Blue, it just classified a Red ball. Now what’s the count, wait what’s the likelihood it misclassified a ball? How accurate are those estimates, and those estimates of those ... For a real world example someone…

Huh? You can derive all of those from Bayesian models. If you're counting balls from a bin with replacement, and your bot has counted 400Red with 637Blue, you have a Beta/Binomial model. That means you p_blue | data ~ Beta(401, 638) assuming a Uniform prior. The probability of observing a red ball given the above p_blue | data is P(red_obs | p_blue) = 1 - P(blue_obs | p_blue), which is calculable from p_blue | data. In fact in this simple example you can even analytically derive all of these values, so you don't even need a simulation!

Re: Effect size is significantly more important than statistical significance

#42
post #2

Speaking not to this study in particular necessarily, I strongly agree with the general point. Science has really been held back by an over-focusing on "significance". But I'm not really interested in a pile of hundreds of thousands of studies that establish a tiny effect with suspiciously-just-barely-significant results. I'm interested in studies that reveal robust results that are reliable enough to be built on to…

Come into Bayesian land, the water is fine. The whole NHST edifice starts to seem really shaky once you stop and wonder if "True" and "False" are really the only two possible states of a scientific hypothesis. Andrew Gelman has written about this in many places, e.g. http://www.stat.columbia.edu/~gelman/research/published/aban... .

Gelman et al's BDA3 has a fun exercise estimating heart-disease rates in one of the early chapters that demonstrates this issue with effect-sizes. BDA3 uses a simple frequentist model to determine heart-disease rates and shows that areas with small population sizes have heavily exaggerated heart-disease rates because of the small base population. Building a Bayesian model does not have the same issue as the prior population prevalence incorporates the small base population sizes.

Re: Effect size is significantly more important than statistical significance

#43
post #2

Speaking not to this study in particular necessarily, I strongly agree with the general point. Science has really been held back by an over-focusing on "significance". But I'm not really interested in a pile of hundreds of thousands of studies that establish a tiny effect with suspiciously-just-barely-significant results. I'm interested in studies that reveal robust results that are reliable enough to be built on to…

p = 0.0001 doesn't help much. You can get to an arbitrarily small p by just using more data. The problem is trying to reject a zero width null hypothesis. Scientists should always reject something bigger than infinitesimally small so that they are not catching tiny systematic biases in their experiments. There are always small biases.

Gwern's page "Everything Is Correlated" is worth reading: https://www.gwern.net/Everything

Re: Effect size is significantly more important than statistical significance

#44
post #38

Earlier quoted context omitted.

Bayesian reasoning has even worse underpinnings. You don’t actually know any of the things the equations want. For example suppose a robot is counting Red and Blue balls from a bin, the count is 400Red and 637Blue, it just classified a Red ball. Now what’s the count, wait what’s the likelihood it misclassified a ball? How accurate are those estimates, and those estimates of those ... For a real world example someone…

Huh? You can derive all of those from Bayesian models. If you're counting balls from a bin with replacement, and your bot has counted 400Red with 637Blue, you have a Beta/Binomial model. That means you p_blue | data ~ Beta(401, 638) assuming a Uniform prior. The probability of observing a red ball given the above p_blue | data is P(red_obs | p_blue) = 1 - P(blue_obs | p_blue), which is calculable from p_blue | data.…

And if misclassification is a concern (as the parent mentioned) you can put a prior on that rate too!

Re: Effect size is significantly more important than statistical significance

#46
post #2

Speaking not to this study in particular necessarily, I strongly agree with the general point. Science has really been held back by an over-focusing on "significance". But I'm not really interested in a pile of hundreds of thousands of studies that establish a tiny effect with suspiciously-just-barely-significant results. I'm interested in studies that reveal robust results that are reliable enough to be built on to…

The problem is that when you’re on the cusp of a new thing, unless you’re super lucky, the result will necessarily be near the noise floor. Real science is like that. But I definitely agree it’d be nice to go back and show something is true to p=.0001 or whatever. Overwhelmingly solid evidence is truly a wonderful thing, and as you say, it’s really the only way to build a solid foundation. When you engineer stuff, it…

> I’ve been thinking about this while playing Factorio: so much of our discussion and mental modeling of automation works under the assumption of perfect reliability. If you had SLIGHTLY below 100% reliability in Factorio, the game would be a terrible grind limited to small factories.

So I'm making a guess here that you play with few monsters or non-aggressive monsters?

Re: Effect size is significantly more important than statistical significance

#48
post #2

Speaking not to this study in particular necessarily, I strongly agree with the general point. Science has really been held back by an over-focusing on "significance". But I'm not really interested in a pile of hundreds of thousands of studies that establish a tiny effect with suspiciously-just-barely-significant results. I'm interested in studies that reveal robust results that are reliable enough to be built on to…

p = 0.0001 doesn't help much. You can get to an arbitrarily small p by just using more data. The problem is trying to reject a zero width null hypothesis. Scientists should always reject something bigger than infinitesimally small so that they are not catching tiny systematic biases in their experiments. There are always small biases. Gwern's page "Everything Is Correlated" is worth reading: https://www.gwern.net/Eve…

It would at least filter out the social science experiments where results on 30 college students is "significant" at p=.04 (and it's too expensive to recruit 3000 of them to force significance).

Re: Effect size is significantly more important than statistical significance

#49
post #38

Earlier quoted context omitted.

Come into Bayesian land, the water is fine. The whole NHST edifice starts to seem really shaky once you stop and wonder if "True" and "False" are really the only two possible states of a scientific hypothesis. Andrew Gelman has written about this in many places, e.g. http://www.stat.columbia.edu/~gelman/research/published/aban... .

Bayesian reasoning has even worse underpinnings. You don’t actually know any of the things the equations want. For example suppose a robot is counting Red and Blue balls from a bin, the count is 400Red and 637Blue, it just classified a Red ball. Now what’s the count, wait what’s the likelihood it misclassified a ball? How accurate are those estimates, and those estimates of those ... For a real world example someone…

Suppose the likelihood it missclassified a ball is significantly different from zero, but not yet known precisely.

If you use a model that doesn't ask you to think about this likelihood at all, you will get the same result as if you had used bayes and consciously chose to approximate the likelihood of misclassification as zero.

You may get slightly better results if you have a reasonnable estimate of that probability, but you will get no worse if you just tell Bayes zero.

It feels like you're criticizing the model for asking hard questions.

I feel like explicitely not knowing an answer is always a small step ahead of not considering the question.

Re: Effect size is significantly more important than statistical significance

#50
post #34

Earlier quoted context omitted.

A few years ago, HN comments complained about the censorship that only leaves successful studies. We need to report on everything we've tried, so we don't walk around on donuts. What's missing in my mind is admitting that results were negative. I'm reading up on financial literacy, and many studies end with some metrics being "great" at p 5%, but then some other metrics are also "great" at p 10%, without the author e…

> ...so we don't walk around on donuts I agree with what you're saying, but I don't understand this phrase.

The phrase "walk around on donuts" has one Google result and it's this thread.
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