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Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

reuters.com

41–50 of 170 posts

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#41

Great story, it’s not quite there yet; finalisation of the testing, and mass production to be done. But with the huge financial and credibility boost I hope the team can follow their passion to solve other medical issues. Quite an insight to switch from cancer therapy to COVID-19 vaccine, and quite the opportunity to be able to deploy 500 researchers onto it at such an early stage. I hope this bolsters their original…

Quite an insight to switch from cancer therapy to COVID-19 vaccine

Actually not at all. BioNTech's entire platform was customized RNA therapeutics that target the immune system to a particular patient's tumor. Basically cancer vaccines.

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#42
post #35

BionTech needs to hire a top tier marketing and PR team immediately, they are failing bad at early media mentions, press releases and coverage. Unfortunately it's probably not within their DNA and they may not realize what is happening around them. This is a monster, monster opportunity and just 'existing' won't leverage it to the extent they can - it will help them fund, hire more, expand more, do more of what they…

So that they will turn into a mega company with nothing but PR, capital and marketing? I think the fact that they are so focused on medicine and science should rather be the norm in medicine.

The fact that Pfizer can spin this story on their name is disturbing and dangeruous behaviour that should not be the norm.

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#43
post #21

Why is Pfizer always mentioned in the news when it is BioNTech and Pfizer is "just" a partner? Just as the Chinese drugmaker Fosun is. Sure credit goes to both but this "Dream Team" is BioNTech.

Similar to the reason why most small biotechs don’t get credit when a big pharma company launches their drug - coming up with a drug candidate is critical and really hard, but it gets you about 1/3rd of the way to the market (at least as measured by dollars). Taking it through clinical trials, regulatory approval and manufacturing is a complex (and massively expensive) process that requires expertise typically only b…

BioNTech is different from a small biotech that can only produce drug candidates. They have their own advanced manufacturing plant and can take it end to end. Their US branch, which my wife is a part of, has all the in-house expertise needed to take a cancer therapy or vaccine to market in the US, just like Moderna does.

If I’m not mistaken the reason for the partnership is the sheer size of the clinical trials needed (very different from cancer therapies) and the speed at which they need to be run due to the pandemic. Only big pharma can do that.

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#44

Why is Pfizer always mentioned in the news when it is BioNTech and Pfizer is "just" a partner? Just as the Chinese drugmaker Fosun is. Sure credit goes to both but this "Dream Team" is BioNTech.

because everything is American and if it is not it either does not exist or it has to be remade in America to be. /snark

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#45
post #38
post #7

Earlier quoted context omitted.

Probably because Pfizer has a big PR department to ensure exactly this.

Şahin was born in Iskenderun, Turkey or Syria before the Turkish/ Ottoman occupation.

The Ottoman empire ended in 1922. He's 55. That math just doesn't add up.

Perhaps you mean the Turkish Republic?

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#48
post #35

BionTech needs to hire a top tier marketing and PR team immediately, they are failing bad at early media mentions, press releases and coverage. Unfortunately it's probably not within their DNA and they may not realize what is happening around them. This is a monster, monster opportunity and just 'existing' won't leverage it to the extent they can - it will help them fund, hire more, expand more, do more of what they…

So that they will turn into a mega company with nothing but PR, capital and marketing? I think the fact that they are so focused on medicine and science should rather be the norm in medicine. The fact that Pfizer can spin this story on their name is disturbing and dangeruous behaviour that should not be the norm.

This is a misunderstanding of what communications is.

The world works on information, if you don't take a seat at table, it will be taken by someone else.

The notion that 'communicating' and 'lab work' would be somehow 'competing time and/or resource pressures' overall at the company is nonsense. They are mostly separate activities.

Pfizer doesn't have to 'spin' anything, they are a legit partner in the deal, they can do the release in the US, they will have their brand up there, their name, do the interviews - and they don't have to do anything tricky, they can surely mention their 'no name partner' and win $1 Billion worth of free PR.

A tiny Germany company, knowing nothing about communications, will miss the opportunity to tell the world who they are, to tell their story, to make their name known to another generation of researchers and scientists who might want to work with them, to a generation of bankers, business people who will be 2x more likely to want to 'take the call and or do the deal' because of their reputation.

1/2 of business is communicating, the only successful businesses that don't understand this are the one's that hit on it accidentally.

Pfizer is already a global brand, this is the moment of a lifetime for 'the name of the company I already forget' (see what I mean?) - I had to re-look it up - 'BioNTech' - it's very much make-or-break. If this vaccine is legit they need to start talking about themselves now.

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#49
post #40
post #10

The headquarter of their company is only 10 miles from my home, in a university town, full of young people. So blessed that maybe a part of the solution to this crisis comes from "my" region.

That's excellent. Well done for being so close. Hope nothing bad happens locally that would ever make you apologise for being where you are (from).

I can't quite tell, are you being sarcastic? If so, I'd just like to point out that there's nothing wrong with being proud of the place where you're from or of the accomplishments of the people of the community there.

Re: Behind Pfizer's vaccine, an understated husband-and-wife “dream team”

#50
post #43
post #21

Earlier quoted context omitted.

Similar to the reason why most small biotechs don’t get credit when a big pharma company launches their drug - coming up with a drug candidate is critical and really hard, but it gets you about 1/3rd of the way to the market (at least as measured by dollars). Taking it through clinical trials, regulatory approval and manufacturing is a complex (and massively expensive) process that requires expertise typically only b…

BioNTech is different from a small biotech that can only produce drug candidates. They have their own advanced manufacturing plant and can take it end to end. Their US branch, which my wife is a part of, has all the in-house expertise needed to take a cancer therapy or vaccine to market in the US, just like Moderna does. If I’m not mistaken the reason for the partnership is the sheer size of the clinical trials neede…

I didn't know they had manufacturing capabilities. Looking at their manufacturing page, they do have GMP manufacturing facilities, but it looks like they were built around their oncology pipeline, which would be customized for each patient and low volume (as you mentioned).

https://biontech.de/how-we-translate/manufacturing

And unless I'm mistaken, they don't have any approved products on market? No doubt they have experts in house, but when you're racing to get a product to market, it can be very helpful having someone like Pfizer helping out who has successfully gotten 70+ products approved by the FDA (including several vaccines).

And interestingly, you'll even see these partnerships across big pharma. I worked for one company who was interested in bringing a gene therapy in house until we did our due diligence and realized holy shit, we know nothing about gene therapies. And this was a top 5 pharma company.

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