41–50 of 247 posts
Please take 10 minutes to get your site on the free cloudflare cache. It's not a good first impression (especially promising scale) not be to able to see it.
Because scaling medical testing is the same as scaling web services...
Please take 10 minutes to get your site on the free cloudflare cache. It's not a good first impression (especially promising scale) not be to able to see it.
Because scaling medical testing is the same as scaling web services...
If you can't be bothered to take some basic steps for web site scaling (google page speed + a CDN) then the idea that you will carefully and successfully navigate to a 1 million tests per day moderate to high complexity medical test seems like it will be a stretch no?
That said, a 100% support MUCh higher test capacity, both this and IGg IGm (which should allow for home testing). So good luck!
Earlier quoted context omitted.
"When you’re fundraising, it’s AI When you’re hiring, it’s ML When you’re implementing, it’s linear regression" The core of our machine learning is Ax=b :grins: More seriously, the main reason why traditional sanger sequencing can't be used for COVID-19 testing is because it would be unclear whether a lack of signal is truly due to lack of virus, or if it is just because the assay failed (happens all the time!) What…
For HN it's better to drop the fundraising language and use the implementing language, so I've s/machine learning/linear regression/'d your text above.
I'm the co-founder and CTO at BillionToOne. I'm happy to answer any questions here. I've also posted a slightly more technical explanation of how the test works and why it can scale here: https://twitter.com/dtsao/status/1247642005510873088?s=21 Edit: Since our site seems to be overwhelmed at the moment, here's a recap: We’ve been working hard at BillionToOne on a new COVID-19 test that scales testing to everyone in…
Thank you for what seems to be a breakthrough with implications beyond even the current outbreak. I had a few questions though: How do you compare this test to the Abbott machines? Obviously that test is faster, but how does that impact what we can do with it? For 1m/day to be sufficient, do we need contact tracing programs to be able to find everybody who needs to be tested? How hard will it be to scale these progra…
I think that where the Abbott machines might hit a wall is that they are one at a time, and they require Abbott's consumable test cartridge and device to run (think printer ink / printer). I don't have any firsthand knowledge, but I would anticipate that it is difficult to scale-up manufacturing of the devices rapidly enough to keep pace with the pandemic growth.
We absolutely need contact tracing to find everybody who needs to be tested. We're not working on scaling up contact tracing, but I think several people in the tech community are working on making that easier to perform at scale.
Earlier quoted context omitted.
Dismissing the value of serological testing seems like a self-serving move. Such tests are immediately of very high value because they allow us to understand immunity to Covid-19, and to actually validate the estimates of cases amongst those who haven’t sought treatment. These are both of huge value regardless of the percentage of the US population estimate to have previously contracted Covid-19. By all means market…
I don't think we are in any way undervaluing the serological tests. A great serological test would be very useful. However, because of the indirect measurement, they tend not to be very sensitive or specific, so it is fair to say that they become more important not at the peak of the pandemic but at the post-pandemic period. By the way, as a company, we really don't have much to gain from this test. If it does not ge…
I'm the co-founder and CTO at BillionToOne. I'm happy to answer any questions here. I've also posted a slightly more technical explanation of how the test works and why it can scale here: https://twitter.com/dtsao/status/1247642005510873088?s=21 Edit: Since our site seems to be overwhelmed at the moment, here's a recap: We’ve been working hard at BillionToOne on a new COVID-19 test that scales testing to everyone in…
Earlier quoted context omitted.
"When you’re fundraising, it’s AI When you’re hiring, it’s ML When you’re implementing, it’s linear regression" The core of our machine learning is Ax=b :grins: More seriously, the main reason why traditional sanger sequencing can't be used for COVID-19 testing is because it would be unclear whether a lack of signal is truly due to lack of virus, or if it is just because the assay failed (happens all the time!) What…
For HN it's better to drop the fundraising language and use the implementing language, so I've s/machine learning/linear regression/'d your text above.
Thanks for your efforts! Inspiring to see our broader community spring into action. I was part of a volunteer team that tested 3400 people on Friday/Saturday in Santa Clara country for COVID-19 antibodies [1]. It took a team of 100+ volunteers 10 hours / day just to collect samples. Stanford, for example, has plenty of automated testing capacity, and even reagents. IMHO, the limiting factors are not that we need new…
Earlier quoted context omitted.
"When you’re fundraising, it’s AI When you’re hiring, it’s ML When you’re implementing, it’s linear regression" The core of our machine learning is Ax=b :grins: More seriously, the main reason why traditional sanger sequencing can't be used for COVID-19 testing is because it would be unclear whether a lack of signal is truly due to lack of virus, or if it is just because the assay failed (happens all the time!) What…
For HN it's better to drop the fundraising language and use the implementing language, so I've s/machine learning/linear regression/'d your text above.
ETA: never mind, ~dvdt signed off on the change. Appreciate the collaboration!
I'm the co-founder and CTO at BillionToOne. I'm happy to answer any questions here. I've also posted a slightly more technical explanation of how the test works and why it can scale here: https://twitter.com/dtsao/status/1247642005510873088?s=21 Edit: Since our site seems to be overwhelmed at the moment, here's a recap: We’ve been working hard at BillionToOne on a new COVID-19 test that scales testing to everyone in…
Your company has filed a US patent application (and it appears also a PCT) on the qSanger method, and this application is reference 8 in your document. What are your plans for licensing the technology?
If they need our bioinformatics automation & help with set-up, we would license the method for COVID-19 testing for $3-$5/sample as part of each sample that is being put through our pipeline.
If they ask for 96-well plates with all reagents that are ready to use (so that they just need to add VTM), we would work with manufacturers to produce the reactions and plates, and the price of kit (~$15 per test) would include limited license to use our automated bioinformatics calling pipeline.