I agree, that looks like it could strike a good relationship for System76 and AMD. Vast, rambling, inexpert conjecture about some of the roadblocks:
The Intel offerings for mobile are very well developed and cost effective. Apple alone pushes quite a bit of development in this segment, in part because lots of us nerds out there with a commit history are running that hardware. Intel can supply powerful, integrated, shrink wrapped subsystems, etc already tailored for mobile form factors. Their marketshare here is crushingly dominant.
Conversely, the AMD mobile platform relies on realtek and others, eliciting howls from grumpy users with certain numbers of greying beard fibers. AMD doesn't supply the ethernet, wifi, storage in this fashion, requiring the integrators to do more work. Making a change will likely be costly, perhaps even riling the, now merely sated, Intel naga from its E-Commerce/Big Data fed slumber, into a veritable springtime of onerous contract terms and volume requirements.
Then there is of course the video subsystem wicket. I have encountered a bunch of anecdotal people that I mentally associate as BSD users who simply prefer the Intel UHD graphics. They like counting on the low power, and simple functionality, as do I. I recognize that AMD has improved by vast geologic scales in the last decade on the drivers and opensource front. I don't fully understand why the graphics haven't enveloped the world. Seems like everyone is happy with Intel UHD-whatever and Mali, or just take what comes and complain if it is buggy.
Additionally there is a mentality of "At least Intel works properly!" that is still floating around a bit, which I don't exactly understand fully. It seems useful to myself, now, to pause and reflect on Intel's ongoing hardware security vulnerability uh--management. Certainly a masterclass of disclosure and mitigation.
Finally, wrapping my afghan around these poor old bones here on my Internet enabled armchair, I wonder what life would be like if the CPU market were more like the automotive industry, and Intel were producing Taxis and Uber vehicles. Would this kind of systemic defect not have been completely ruinous? Much different industry of course, but one thing makes me chuckle--maybe those banks shelling out for those 30 year old Mainframe support contracts had the right idea all along.