Earlier quoted context omitted.
For others reading, this appears to be because he believed that in an accident the radio-thermal isotope generator on board Cassini would spread radioactive material all over the place.
...all over the place A small, but possible chance of Pu-238 spreading over Florida. I just read that 238 (half-life 87 years) emits mostly alpha, which is said to be easily blocked, even by paper. In FL, many go about half naked, so I'm not sure if this matters. I wonder how thoroughly Kaku considered everything. Seems his concern was based partially on NASA's (small but not null) history of failures. I don't know,…
(Not agreeing with Michio Kaku, by the way.)