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23andMe Informed Me My Husband and I Are Related

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Re: 23andMe Informed Me My Husband and I Are Related

#42

You share (about) 1/128 of your genes with a third cousin. The chance of any (particular) recessive trait being passed on from both parents as a result of the inbreeding is a whopping 1 in 65,536.

I'm not sure what you computed. The interesting question is to pick a recessive trait from one of the parents and ask for the chance of it being passed on. The probability that it's being passed on from the parent who has it is 1/2. The probability that it's being passed on from the other parent is (1/2)*(1/128). The combined probability is 1/512, not 1/65,536.

Re: 23andMe Informed Me My Husband and I Are Related

#43
A relative of mine who is a doctor mentioned to me that the opposite is a common problem when children volunteer to donate an organ to a parent. They must test for DNA compatibility which often yields bad surprises. Apparently it is gradual. The DNA of the first child almost always matches, the second a little less, the third is where the odds reduce significantly.

Granted that was in France...

Re: 23andMe Informed Me My Husband and I Are Related

#44
post #35

The author using the word "mansplaining" disqualifies her from any hint of professionalism

The word wasn't used in the pejorative sense in the article.

Still, it's attempting to normalize this term in people's dictionary.

Re: 23andMe Informed Me My Husband and I Are Related

#45

I work in genomics. My lab, many of my friends and acquaintances work in genomics or had to dabble with it for at least one of their projects. You would think we would all be fascinated by this stuff, getting to know your own DNA and everything. Yet I don't know a single person who would even consider using 23andMe's service. To me this is all an elaborate scam. Why on earth would you pay them to give them your data…

> With this company you end up $100 (or whatever) short and you surrender your data for it to be sold to ... .... insurance companies and whatnot.

False ! Source : https://www.23andme.com/about/privacy/

We will not provide any person’s data (genetic or non-genetic) to an insurance company or employer.

Re: 23andMe Informed Me My Husband and I Are Related

#46
post #45

I work in genomics. My lab, many of my friends and acquaintances work in genomics or had to dabble with it for at least one of their projects. You would think we would all be fascinated by this stuff, getting to know your own DNA and everything. Yet I don't know a single person who would even consider using 23andMe's service. To me this is all an elaborate scam. Why on earth would you pay them to give them your data…

> With this company you end up $100 (or whatever) short and you surrender your data for it to be sold to ... .... insurance companies and whatnot. False ! Source : https://www.23andme.com/about/privacy/ We will not provide any person’s data (genetic or non-genetic) to an insurance company or employer.

Some great things about companies that you can always count on:

- They never change their terms of service

- The demand for constant growth never causes them to reconsider ethically dubious revenue streams

- They never get acquired

Re: 23andMe Informed Me My Husband and I Are Related

#47
post #45

I work in genomics. My lab, many of my friends and acquaintances work in genomics or had to dabble with it for at least one of their projects. You would think we would all be fascinated by this stuff, getting to know your own DNA and everything. Yet I don't know a single person who would even consider using 23andMe's service. To me this is all an elaborate scam. Why on earth would you pay them to give them your data…

> With this company you end up $100 (or whatever) short and you surrender your data for it to be sold to ... .... insurance companies and whatnot. False ! Source : https://www.23andme.com/about/privacy/ We will not provide any person’s data (genetic or non-genetic) to an insurance company or employer.

Curious. Is that binding forever? Are they not allowed to ever change that and then retroactively give out data?

Re: 23andMe Informed Me My Husband and I Are Related

#48
post #19

Third cousins sounds like a non-issue to me, and it sounds like the author and spouse generally agree. I've never knowingly met any second cousins or any other descendants of my great-grandparents (who are not also in my grandparents' lineage). I wonder if there are any estimates on how common unaware third-cousin marriages are.

It’s interesting how much that can vary. I’ve met every one of my second cousins on 3 out of 4 family branches (one grandparent was estranged from their family). Those who live nearby I’m closer with than first cousins who live further away.

My and my siblings’ children will also know some of their third cousins, and see them at least once every few years at holidays.

I’ve met a couple third cousins, and am fairly certain with any others (aside from that one branch of the family), we’d discover our relationship well before being together long enough to consider marriage.

That said, I wonder to what degree physical proximity plays a role. If the second cousins didn’t for the most part live in the same metro area as the entire rest of the family, we’d probably see them even more rarely than the set of first cousins who live a 3-hour flight away - which is to say, roughly once a decade.

Re: 23andMe Informed Me My Husband and I Are Related

#50

Earlier quoted context omitted.

You don't have to provide them with your real name. Also, I work in genomics and am a 23andme customer/product (although I was the latter before I the former became true).

I travel a fair bit and stay at the hotels here and there. I keep wondering, how long before hotels start sampling your personal belongings (toothbrush, comb etc) for gen data. Maybe that already happening? From there, how long before full lists of these data {genetic sample; full name and other credentials} are on sale on some special market? Call me paranoid... is that sort of activity even regulated? Isn't this li…

Well, if we're being paranoid they probably don't need to touch your personal belongings. They just have to have a look at the bed sheets after you've slept on them.

...or to get your DNA they can work it out from the "deposited" DNA of your close relatives. There will be no hiding! :P

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