When the first stage elections are contested among isolated ideological subsets of the electorate their results tend to extreme positions.
What I'm saying is this: it is inevitable that the REDMAP project that yielded the kinds of district-level results shown in this article will continue to generate more and more extremist election results.
Ryan and McConnell, and the whole US federal house of representatives, have bought and paid for their dysfunction with this systematic gerrymandering. The situation isn't going to improve as long as this holds.
Pouring money into contesting the general elections in these districts is entirely a waste. It enriches nobody but robocall and television companies, and doesn't affect the outcome.