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Acid reflux drug linked to more than doubled risk of stomach cancer

theguardian.com

41–50 of 85 posts

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#41
> “The most plausible explanation for the totality of evidence on this is that those who are given PPIs, and especially those who continue on them long-term, tend to be sicker in a variety of ways than those for whom they are not prescribed.”

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#42

> “The most plausible explanation for the totality of evidence on this is that those who are given PPIs, and especially those who continue on them long-term, tend to be sicker in a variety of ways than those for whom they are not prescribed.”

After being on Prilosec for 2 years, I had an endoscopy and the pictures of the inside of my stomach were odd. Little bumps over the entire inside. I asked the doc and he said "we don't think those are a problem". Right. I got off it immediately.

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#43
post #30

Nothing gives you a morning dose of fear like reading this about a drug you’ve been on for 6 years. Guess I’ll start looking into alternatives and ways to screen for stomach cancer.

I've been on prilosec close to 15 years. Unfortunately H2 blockers don't seem to work for me. I'm not sure what to do. I can go without it for a month or so, then crippling stomach pain and indigestion happens.

Check for gallstones.

I had that, crippling stomach pain, which was initially diagnosed as either gastritis or possibly an ulcer. However, after dealing with it for a couple years, I ended up in the emergency room. They ran an ultrasound, and found a number of gallstones lodged in the duct that connects the gallbladder to the stomach. Ended up having my gallbladder removed.

Items that I remember triggering massive pain attacks include pizza (I thought it was acid from the tomato sauce, but it was fat from the cheese), and after eating a large gyro (lots of fat in it apparently). Fat causes the gallbladder to start pumping, and if there are stones it will lodge them in the duct causing the pain.

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#45
post #30

Nothing gives you a morning dose of fear like reading this about a drug you’ve been on for 6 years. Guess I’ll start looking into alternatives and ways to screen for stomach cancer.

I've been on prilosec close to 15 years. Unfortunately H2 blockers don't seem to work for me. I'm not sure what to do. I can go without it for a month or so, then crippling stomach pain and indigestion happens.

Try reviewing your diet, the times when you eat and drink plenty of water. Mercola's solutions worked for me. 'acid reflux' - https://articles.mercola.com/sites/current.aspx

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#46
post #40

Just to cast the exact same finding in a different way, this appears to raise the incidence rate of stomach cancer from 0.8% to 1.6%.

So where do these numbers come from? Who was in the study and where was it done?

my numbers are overall cofirmed incidence rates. CDC has them.

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#48

People don't realize PPIs are a short term solution. PPIs are terrible long term. That being said, I'd be long dead without them. They are truly a life saver until you find out the root cause. Many trips to the ER and years later, I found out avoiding gluten and taking probiotics cured mine.

A couple of months into my low carb diet, I realized I hadn't taken any (because I would only take them when I felt symptoms).

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#49
post #34

Nothing gives you a morning dose of fear like reading this about a drug you’ve been on for 6 years. Guess I’ll start looking into alternatives and ways to screen for stomach cancer.

Seriously. I've been taking it sporadically for about that long as well. Doing the same as you now.

It's much more likely that those taking such drunks, are at a much higher disposition of developing such complications.

I started taking such a drug again after developing stomach issues. I had a scare a couple of years ago, and it was only by chance that I changed to another GP who was much more attentive, turned out that I was only months away of having a haemorrhage that would have likely been fatal. All from a few years taking a 'safe' anti-inflammatory. Now I won't touch any NSAIDs (which is a shame as I'm in more pain), but it isn't worth the risk of further damage, which was left me as a coeliac (body went after the wrong target).

How often do you read about NSAIDs? No, it's how Fentanyl is killing so many heroin addicts, yet the patches are safely used by millions.

Re: Acid reflux drug linked to more than doubled risk of stomach cancer

#50
post #43
post #30

Earlier quoted context omitted.

I've been on prilosec close to 15 years. Unfortunately H2 blockers don't seem to work for me. I'm not sure what to do. I can go without it for a month or so, then crippling stomach pain and indigestion happens.

Check for gallstones. I had that, crippling stomach pain, which was initially diagnosed as either gastritis or possibly an ulcer. However, after dealing with it for a couple years, I ended up in the emergency room. They ran an ultrasound, and found a number of gallstones lodged in the duct that connects the gallbladder to the stomach. Ended up having my gallbladder removed. Items that I remember triggering massive pa…

And if you have gallstones, ride a rollercoaster! Specifically Disney World's Magic Kingdom Big Thunder Mountain Railroad. http://www.cnn.com/2016/09/28/health/kidney-stone-roller-coa...
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