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GLP-1 drugs: An economic disruptor? (2024)

wildfirelabs.substack.com

391–400 of 553 posts

Re: GLP-1 drugs: An economic disruptor? (2024)

#391

Earlier quoted context omitted.

6th option: They are overweight, but do not know, so they don't recognize what overweight looks like. But also, it's pretty easy to not look overweight if you're not obese. 30 pounds can be as little as a few waist sizes. I can gain and lose 15 pounds without looking like I changed at all.

I am 6ft and 165lbs and work with a bunch of overweight people. They are normal weight and I desperately need to eat something - according to them.

Same weight, but I'm 6ft6. At that point even my doctor would repeatedly tell me to eat more.

Re: GLP-1 drugs: An economic disruptor? (2024)

#392
post #219

Off topic: Since we are doing clickbait titles, I thought ChatGPT / Gen AI in general might be a better candidate for "the biggest economic disruptor since the internet", based on hype, especially from the "leaders" who claim that AGI is just a few months away.

[deleted]

Re: GLP-1 drugs: An economic disruptor? (2024)

#393

This is just the start. Those in the know are already stacking: GLP-1 Agonists, Senolytics, NMDA Modulators, Hormones and Peptides, NAD+ and mTOR Modulation, Nootropics and Adaptogens… Forget weight loss. These people are going for immortality.

no Just-In-Time crispr gene editing as the cherry on top??

Re: GLP-1 drugs: An economic disruptor? (2024)

#394
post #330

Earlier quoted context omitted.

when semaglutide and tirzepatide first came out, they were being synthesized in labs across the world for pennies per milligram, as with all compounds.

Yeah unfortunately that’s about to come to an abrupt end

how so? the last i checked, the prices are going down, not up (from the biolabs that manufacture the peptides)

Re: GLP-1 drugs: An economic disruptor? (2024)

#395
post #30

I'm from the country of Ozempic and Wegovy and neither Novo Nordisk nor our media have been portraying these drugs as general purpose anti-addiction drugs. However there have been some international studies that reveal that it might actually be. Can Novo Nordisk extend their patent of their existing drug if they find new applications for the drug? Some of Silicon Valley's excess productivity over the rest of the worl…

same to your last point

as another person mentioned in this thread about people already combining glp's with other drugs, i can see scenarios in which some people abuse glps with adderall or even pain killers to become literal zombies - foregoing breakfast/lunch breaks, working longer hours... imo it could establish an even greater work demand from companies (implicitly) where if you're not on it, you're not "trying" hard enough.

Re: GLP-1 drugs: An economic disruptor? (2024)

#396

Earlier quoted context omitted.

Suppose a country had very low rates of depression, and another had very high rates. Is that just brain chemistry? Or does maybe one country have problems that cause many people to have depression? Or to push subclinical tendencies into clinical territory? The US is that but for obesity. Yes, absolutely some individuals have brain chemistry that predisposes them to this. But also maybe it's related to the cheapest an…

https://data.worldobesity.org/rankings/ https://www.who.int/activities/controlling-the-global-obesit... The US isn’t even the top 9. Obesity is a global epidemic of Western disease. The food isn’t the cause, it’s the symptom of the brain chemistry. If it isn’t available, yes, the disease may not present. But if available, due to hormones causing the drive , it presents. Like cigarettes (nicotine), like cocaine, like…

Nobody was suggesting solutions, but in regards to GLP-1 agonists as solving the 'problem' perfectly, no, it's just solving the symptoms. The problem is scientific advancement creating hyper palatable food and drink with no nutritional value and low satiety, combined with the food drive increases that comes with eating and drinking that food, combined with the removal of general fitness and mobility as a core requirement to being able to receive food and drink. I'm not saying there's a way to put back in the box but let's not kid ourselves that these drugs are a perfect solution either.

Re: GLP-1 drugs: An economic disruptor? (2024)

#397

Earlier quoted context omitted.

> Yes well your PCP / pharmacist should not have prescribed you an appetite suppressant when you have below average body fat %. Why do you think this? I agree that people who have associated risk factors should be prioritized, but if there's enough for everyone why wouldn't we give it to anyone who wants it?

People who don't need to be chronically medicated should not be. There are always side effects, and we don't even know for sure what the long term risks of these medications are yet. And crowing about saving $200/mo not buying food at Starbucks, well now Novo Nordisk is getting that. Toast a bagel at home for $0.50/day instead.

This really just seems like a shit take to me. Everything has side effects, that doesnt mean everything is a net negative. People should be able to weigh the pros and cons of chronic medication and decide if it improves their life.

Re: GLP-1 drugs: An economic disruptor? (2024)

#398

Earlier quoted context omitted.

No it hasn’t— its well researched and the short to mid term (ish) side effects are well known: https://glp1.guide/tag/category-side-effects/

[flagged]

> blindness, osteoporosis, depression, digestive and metabolic issues

I believe each of those are listed in the link he provided. It's up to the individual to make their own decisions as to their own health. At least the information exists with which to make informed decisions.

Re: GLP-1 drugs: An economic disruptor? (2024)

#399

Big food corporations profit from ultra-processed foods that manipulate our natural systems. They design products that override satiety signals using calculated combinations of sugar, fat and salt to activate brain dopamine pathways. Their priority is profit growth, not consumer health. The consequences are significant health issues like obesity, diabetes and cardiovascular diseases. Healthcare systems struggle with…

I actually feel the opposite. Ozempic is a massive risk to health food companies. When people know they can eat whatever they want and not gain weight they'll only eat what tastes best. All mcdonalds no sweet green so to speak.

Re: GLP-1 drugs: An economic disruptor? (2024)

#400
post #56

The author is assuming that everyone will proactively start taking this drug. But I don't understand why? If Jerry is not obese, why would Jerry randomly start taking an anti-obesity drug?

Because the author assumes that the drugs are not only anti-obesity drugs but impulse controlling

Even if they are right, do people want to voluntarily start taking drugs to control their impulses? Au contraire, I think a lot of people, either ideologically or subconciously, appreciate the hedonistic lifestyle
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