391–397 of 397 posts
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> The only valuable conversation about such research is an objective discussion of the quality of the study at hand. No People's lived experience is very useful
Those are called anecdotes. Empirically, they're usually not nearly as useful as people think. People are on average unreliable observers of their own experiences. Much better than individual anecdotes are collections of anecdotes that are searchable and somewhat categorized. A lot of old school drug forums provide this. Much better still is systematically varying data and taking statistics to separate signal from no…
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just consider, if it's so powerful in adjusting his brain, it's probably equally powerful in adjusting anybody's brain, and what if your brain doesn't need adjustment? there's no reason to think it's "idempotent" so to speak. https://en.wikipedia.org/wiki/Idempotence is the property of certain operations in mathematics and computer science whereby they can be applied multiple times without changing the result beyond…
I suspect there’s a lot of self selection at work already. The vast majority of people don’t jump straight into psilocybin and LSD, they progress to them by taking softer drugs like alcohol and cannabis. I think a lot of people who don’t need “adjustment” figure out drugs don’t do much for them and stop before they take the intense psychedelics, or they figure it out at lower doses and stop before they take the inten…
From my personal experience, SSRI (zoloft) felt like a temporary coffee-like stimulant. Psilocybin (or easier to handle synthetic analog 4-aco-dmt) provided short-acting relief from depression and some new perspectives. But ketamine is truly a magic pill if done right. After glow is about a month, and the trip takes 2-3 hrs max. FDA-approved, see Spravato. I feel like at some point ketamine therapy at scale would make SSRIs obsolete, it's just better and faster.