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Schizophrenia is the price we pay for minds poised near the edge of a cliff

psychiatrymargins.com

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Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#381

Post by mandmandam »

talentedcoin wrote: post #342
mandmandam wrote: post #270

Earlier quoted context omitted.

> I don't believe you. If you had, you would have led with it, just like I did. You really can't imagine someone arguing from scientific research over their own personal experience? > Jenny McCarthy is a big fat pain in the ass Again with the autism/vaccines comparison, again missing the point, again doing yourself and your family member a disservice. > WTF? I've never believed that crap in my life. You keep repeatin…

The one paper you keep shopping around here does indeed affirm that CBD may have some neuroprotective properties. That doesn’t change the fact that for the vast majority of people susceptible to schizophrenia or psychosis, that cannabis (always a mixture of THC and CBD in its natural state) is dangerous for them and can trigger mental issues. You can feel superior or more intelligent than others as much as you like,…

> cannabis (always a mixture of THC and CBD in its natural state)

Come on man, I've been explicit from the start that I'm talking about high CBD low THC strains. If you refuse to acknowledge that then you're wasting both our time.

> You can feel superior or more intelligent than others as much as you like,

Weird thing to throw out there. Do you often feel like people giving you more information is an assault on your intelligence or value as a person? Is that helpful for you? ...

> You are getting a negative reaction from people who know this because we have been negatively affected by it

By high CBD, low THC cannabis? Be honest now.

> If you yourself “engage with the research” beyond your tunnel vision, you will see that the link between cannabis and mental issues is pretty well established by this point

I never denied there's a 'link'. There's clearly a link, but to claim that it's well understood is a gross exaggeration, and insisting that it applies to high CBD low THC cannabis is an obvious lie (no matter how many times you repeat it).

> refusal to acknowledge downsides of cannabis use is one of the hallmarks of cannabis use disorder. Pluck the beam out of your own eye.

Now you're implying I have a disorder and a drug problem? Even though at no point have I "refused to acknowledge downsides of cannabis".

So, recapping: I posit that high CBD low THC cannabis could help schizophrenics. I provide multiple links to researchers in this field saying the same thing. And by doing this, you feel entitled to make to accusations of me being a drug dealer, having a substance abuse problem, a superiority complex and a mental disorder?

... It's not ok to talk to people like that. And yet you end all that with "pluck the beam out of your own eye"; as if I were the one casting judgment??

[https://i.ytimg.com/vi/eeEyVZiVW_M/hqdefault.jpg]

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#382

Post by poulpy123 »

crtified wrote: post #47
winrid wrote: post #15

Earlier quoted context omitted.

If you have a genetic predisposition to schizophrenia it's starting to seem like drugs that seem harmless like marijuana (specifically THC?) can definitely bring it out. At least, that's what seemed to happen to my mother and another friend.

I wonder if alcohol is one of the seemingly harmless drugs whose abuse catalyzes such conditions in susceptible people. Because, if so, then alcohol's ubiquity in society would imply that it is probably responsible (in the sense that substances are responsible) for most such conversions.

Nobody serious believe that alcohol is harmless. There are many anti-alcohol campaign and laws always running around. It's just that alcohol has been part of our culture for thousands of year, that we monstly manage it. It's not the case of cannabis, psilocybin and even less LSD (even if you can find historic usage for the not man made ones)

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#383

Post by Raphell »

I know someone who had a clear psychotic break and still hasn't fully recovered. The scariest part wasn't when he lost control. It was that he truly believed everything made perfect sense. The more you tried to care for him, the more he thought you were acting and trying to manipulate him.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#385

Post by johnisgood »

heavyset_go wrote: post #354
johnisgood wrote: post #344

Earlier quoted context omitted.

Also known as "delirium". They cause delirium. Benadryl (DPH) for example does that. It is very dysphoric.

Lower doses can induce hallucinations before it becomes full on delirium that you see in higher doses. You'll regularly hear about people seeing "spiders" after taking 25-50mg of Benedryl, the recommended dose.

I think that may be more common in the elderly. I had full-on delirium from 5 x 50 mg, however. I would not recommend. It took me months for my body to recover. The auditory hallucinations lasted the longest (2-3 days), but my body and my mind was a wreck for months. Thanks to our beautiful hospital that did not administer the antidote for anticholinergic toxicity.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#386

Post by balanced2 »

vbezhenar wrote: post #202
bettercallsalad wrote: post #75

As someone who is currently dating someone with history of psychosis, I have vested interest. 90% of the time she is truly the most amazing, compassionate, full of life and thoughtful person one can ever meet. Then there are times when it’s truly awful. She can barely sleep at all, leaves house without telling anyone seemingly thinking the presence of third person around. And she strongly feels others around are judg…

She will break down, then she'll get strong meds and she'll change unrecognizably. Think twice before making a long relationship with this person. You'll get a lot of stress and eventually she'll change drastically. Schizophrenia has a strong genetic component, so think twice about making a children as well.

The original article does point out the polygenic nature of the disease.

Currently dealing with a schizophrenic brother-in-law randomly calling for the death of his wife. They have a 2-year-old. I have high hopes for her though, but not for the ability for HN commenters to be able to make empathetic comments instead of random barking.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#388

Post by Aeglaecia »

overu589 wrote: post #266
lucidrains wrote: post #260

Earlier quoted context omitted.

I am sorry to hear that.

Don’t be. After nearly two decades of development I experience the precipice of humanity. The state of the art of human consciousness. I have peered beyond the veil and what I see is terrifying yet truth.

i would be much obliged if you were to share insight derived from force disagreement with concensus reality

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#389

Post by LoganDark »

wasabi991011 wrote: post #372
shippage wrote: post #362

Earlier quoted context omitted.

I have met a few people online who told me they were diagnosed with both. Schizophrenia spectrum disorders (SSDs) and DID can apparently co-occur. From [0] (2016): > One study showed that in a sample of patients diagnosed with Dissociative Identity Disorder (DID) 74.3% also met diagnostic criteria of a SSD, 49.5% met diagnostic criteria for schizoaffective disorder, and 18.7% met diagnostic criteria for schizophrenia…

I'd be willing to try institutional academic accounts if you ever have some paywalls article you want to read. Just shoot me an email at partner_privacy@proton.me Also, my partner likely has DID and is struggling with it somewhat. If you have advice or are willing to answer some questions, I'd appreciate talking about it. But I know it's a big ask, respectfully, so I understand if not.

We also have DID and would also be open to talking; you can find our contacts on our Keybase (or contact us on Keybase itself).

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#390

Post by LoganDark »

quickthrowman wrote: post #188
winrid wrote: post #15

Earlier quoted context omitted.

If you have a genetic predisposition to schizophrenia it's starting to seem like drugs that seem harmless like marijuana (specifically THC?) can definitely bring it out. At least, that's what seemed to happen to my mother and another friend.

Or perhaps people predisposed to schizophrenia are more likely to seek out drugs. Something like 9 in 10 schizophrenics smoke cigarettes too, is schizophrenia caused by nicotine or do schizophrenics smoke because they’re predisposed to do so? I find it hard to believe that so many schizophrenics smoke cigarettes and are not also predisposed towards using other drugs. I think blindly accepting the statement ‘drugs can…

Some drugs have been known to activate schizophrenia; particularly psychedelics like LSD. However, in order for this to happen, one likely already needs to have a genetic predisposition. I use LSD about once every week or two and I haven't noticed any schizophrenia yet, so it is very much a YMMV.
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