Earlier quoted context omitted.
It's hard to find a full size bluetooth keyboard. I think I went through every keyboard on Amazon and found only one. If you use a USB wireless keyboard, well, there goes one of the two USB slots on the laptop. It's not just the monitor being big, I want lots and lots of pixels. I'm currently running 3840*2160, and have a second monitor attached set up in portrait mode (so I can display a manual page while I work on…
I don't see a lack of USB ports as a complete dealbreaker for using a laptop. USB hubs work fine to attach large numbers of lower-speed USB devices to a laptop.
It's a dealbreaker for me.