Earlier quoted context omitted.
The Walgreens pharmacist scolded my 35 year old girlfriend for getting it, saying that it was useless at her age. She insisted and he reluctantly administered the first dose (and later got the rest at another location). He even questioned her motives for getting it once she was in the room. I was appalled by the whole interaction. Maybe I could have understood if I had said she was my wife. But it is still stupid to…
HPV is approved up to age 45 with “shared clinical decision making”. Above age 26 it may be more difficult without a clinician due to unimportant bullshit. Try a Planned Parenthood.
Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
371–380 of 393 posts
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#372Earlier quoted context omitted.
> The overwhelming majority of cervical cancers occur in Africa due to the fact that HIV/AIDS dramatically increases your susceptibility to developing it. Considering we're talking about a sexually transmitted disease, the much higher prevalence in Africa of having multiple simultaneous sexual partners is surely relevant.
> having multiple simultaneous sexual partners is surely relevant. medically, not really. the vaccine acts the same. epidemiology wise, it makes it more effective, assuming the correct coverage. I would just suggest that stating that an entire continent of different races/culture/religions "having multiple simultaneous partners" smells just a little bit of "savages over there", which given that we are talking about _…
That's not a response. The multiple simultaneous sexual partners are relevant to the fact that prevalence of the disease in Africa is very high. This is not a vaccine-related question, so the action of the vaccine can't speak to it.
> I would just suggest that stating that an entire continent of different races/culture/religions "having multiple simultaneous partners" smells just a little bit of "savages over there"
Funny, if you look at my comment, you should see that it refers to "the much higher prevalence" of this behavior in Africa.
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#373If you're living in the US: please consider getting the vaccine, ragardless of your age. It was covered by my (rather shitty) health insurance. It consists of just 2 (EDIT: 3 for adults!) doses. It is recommended for both Males and Females.
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#374Earlier quoted context omitted.
It's less that and more "we just haven't tested it in older populations yet". Sure you are more likely to have it the older you are but even then you are unlikely to have all the strains. The vaccine covers like 9 or 10 different strains so it can protect you from the other strains even if you already have one of them. It's generally only when you get into the 60s and up that the justification for not recommending th…
> you are recommended to get the shingles vaccine instead of the chickenpox vaccine since the way the disease presents and how the body reacts to it changes with age (technically shingles can happen at any age but generally herpes zoster presents as shingles instead of chickenpox the older you get). If the underlying virus is the same, what is different between the vaccines? How it presents shouldn't matter as much?
The shingles vaccine is a larger/more aggressive dose than the chickenpox vaccine.
And nowadays chickenpox vaccine uses live attenuated viruses (i.e. modified to be non-infectious but still look the same) whereas the shingles vaccine uses recombinant proteins. This allows the shingles vaccine to deliver the higher viral load that they want for inoculating against shingles without putting a bunch of live viruses into the body.
It's also worth noting that the recombinant vaccine is more effective for shingles compared to the equivalent viral load live vaccine by a significant margin. It's something like 90% reduction in incidence vs 50%.
----------
> How it presents shouldn't matter as much?
It's not an all or nothing thing but it's a matter of percentages.
And the big reason why they present differently is that chickenpox kind of attacks every part of the body since it's new. It of course does best at infecting the skin and nerves but it mildly affects every part of the body. But then it goes dormant in the nerves because that's where it's most "compatible" and the body is the worst at fighting it.
So then with shingles your body still has the immunity but the reactivated virus is able to out-compete your immunity in the nerves and it wakes up in whatever specific nerve and spreads along that nerve. This is why shingles generally presents in a band on the body. It's spreading along a specific nerve "line" rather than spreading throughout the whole body, blood, and all.
And so the because the infection can't spread broadly throughout your body it ends up concentrated in that location and presumably the higher viral load combined with focusing on the specific proteins rather than the whole virus increases the body's sensitivity to these flair ups, catching them before they can reach momentum. And then that focused immune training sits on top of the body's existing immunity for the initial "whole body" presentation of the virus.
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#375Earlier quoted context omitted.
I'm sorry, but you sound like the people who try to get me take ivermectine for Covid. "just get it off label" or "tell the doctor you just got back from pauea new guinea and saw worms in your stool." I know you are very well intentioned, but American's actually have very good doctors.
This is very different from recommending horse dewormer; if you can't tell the difference, I'm sorry.
> Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis. It works through many mechanisms to kill the targeted parasites, and can be taken by mouth, or applied to the skin for external infestations.] It belongs to the avermectin family of medications.
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#376Earlier quoted context omitted.
the cdc decides to make recommendations no matter how expensive, and big pharma collects the expensive, and the expert community works for the cdc and big pharma? do you even understand what regulatory capture is? do you understand how framing something as saving lives no matter the cost draws attention away from funneling money to big pharma no matter the deficit? let me guess, you work in this area too.
Since you already replied to my other comment, hopefully you understand now that ACIP takes into account cost as part of its recommendations, but the independent group we were talking about in this thread does not. Even with CDC its recommendations, it's not the final word. The reasoning you're highlighting here is highly conspiratorial
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#377There is recent research showing that it can (slightly) help even during HPV infection, see "Effect of HPV Vaccination on Virus Disappearance in Cervical Samples of a Cohort of HPV-Positive Polish Patients", J Clin Med (2023) https://pubmed.ncbi.nlm.nih.gov/38137661/ . Also, the eligibility criterion of not vaccinating people above certain age is NOT valid. I mean, sooner better. But if you are adult and there is any…
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#378https://www.quebec.ca/en/health/advice-and-prevention/vaccin...
Now they're offering it to children as part of the standard regimen, which is great.
Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#379Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out
#380Earlier quoted context omitted.
> having multiple simultaneous sexual partners is surely relevant. medically, not really. the vaccine acts the same. epidemiology wise, it makes it more effective, assuming the correct coverage. I would just suggest that stating that an entire continent of different races/culture/religions "having multiple simultaneous partners" smells just a little bit of "savages over there", which given that we are talking about _…
> medically, not really. the vaccine acts the same. That's not a response. The multiple simultaneous sexual partners are relevant to the fact that prevalence of the disease in Africa is very high . This is not a vaccine-related question, so the action of the vaccine can't speak to it. > I would just suggest that stating that an entire continent of different races/culture/religions "having multiple simultaneous partne…
Does Ghana have a higher or lower prevalence compared to benin, egypt or eritrea?