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GLP-1 drugs: An economic disruptor? (2024)

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Re: GLP-1 drugs: An economic disruptor? (2024)

#371

Post by crazygringo »

Etheryte wrote: post #298
crazygringo wrote: post #229

Earlier quoted context omitted.

> Big food corporations profit from ultra-processed foods that manipulate our natural systems. I've just never bought this. Does grandma manipulate you when she adds sugar to her cherry pie? Does she manipulate you when she adds salt to her mashed potatoes? Foods -- "ultra-processed" or not -- don't "manipulate" you. They literally just either taste better or taste worse. Grandma, and her grandma before her, used sug…

Many foods and beverages include ingredients whose sole purpose is to hide how sweet it is because otherwise it would be unbearable in your mouth. Gives you a stronger high once it reaches your stomach though.

I don't know where you got that information, but no they don't. That's not a thing. You were misinformed.

Re: GLP-1 drugs: An economic disruptor? (2024)

#372

Post by Workaccount2 »

xboxnolifes wrote: post #89
brokensegue wrote: post #26

Earlier quoted context omitted.

40% of Americans are obese and way more are merely overweight. Either your office is small, a huge fluke, weirdly selected or you're not observant enough.

6th option: They are overweight, but do not know, so they don't recognize what overweight looks like. But also, it's pretty easy to not look overweight if you're not obese. 30 pounds can be as little as a few waist sizes. I can gain and lose 15 pounds without looking like I changed at all.

I am 6ft and 165lbs and work with a bunch of overweight people. They are normal weight and I desperately need to eat something - according to them.

Re: GLP-1 drugs: An economic disruptor? (2024)

#373

Post by crazygringo »

walleeee wrote: post #282
crazygringo wrote: post #229

Earlier quoted context omitted.

> Big food corporations profit from ultra-processed foods that manipulate our natural systems. I've just never bought this. Does grandma manipulate you when she adds sugar to her cherry pie? Does she manipulate you when she adds salt to her mashed potatoes? Foods -- "ultra-processed" or not -- don't "manipulate" you. They literally just either taste better or taste worse. Grandma, and her grandma before her, used sug…

Does grandma have a profit motive? Does grandma care about your wellbeing? Is grandma a vast conglomerate of strangers who couldn't give two flying fucks about you on a good day? Is plain old sugar, animal fat, and salt unhealthy in large quantities? Of course, but eating grandma's mashed potatoes and cherry pie once a week will not materially affect your health. Meanwhile you pass 8 taco bells on your way home from…

Right. But that's my whole point, you're agreeing with me.

It's not the food itself. The food isn't being "manipulated" in some sinister, unnatural way. It's not about supposedly addictive "dopamine pathways".

It's other things, whether convenience or advertising or whatever.

Re: GLP-1 drugs: An economic disruptor? (2024)

#374

Post by xboxnolifes »

Workaccount2 wrote: post #372
xboxnolifes wrote: post #89

Earlier quoted context omitted.

6th option: They are overweight, but do not know, so they don't recognize what overweight looks like. But also, it's pretty easy to not look overweight if you're not obese. 30 pounds can be as little as a few waist sizes. I can gain and lose 15 pounds without looking like I changed at all.

I am 6ft and 165lbs and work with a bunch of overweight people. They are normal weight and I desperately need to eat something - according to them.

I was going to add this exact comment to me post originally. You're me, but with my family.

Re: GLP-1 drugs: An economic disruptor? (2024)

#375

Post by CMCDragonkai »

hombre_fatal wrote: post #312
crazygringo wrote: post #267

Earlier quoted context omitted.

See, now we're talking. That's my point. It's got nothing to with supposed "manipulation" of ingredients. It's about other stuff -- whether it's price or accessibility or someone telling you "that's enough".

Yeah, I agree. People really seem desperate to believe it all comes down to boogeyman adulterants, but it's a huge red herring and completely unnecessary for ending up with a culture of junk food, obesity, and calorie surplus. Drop dough into frying oil and then roll it in powdered sugar. Drop potato slices into frying oil and then salt them. You don't need boogeyman R&D chemicals to make food that you can't stop eat…

It is far more likely that the obesity crisis is a combination of a lack of healthy food culture combine with industrial revolution of mass produced food capacity. Since you don't want to drop your industrial capability, the only other option is to change societal food culture and their relationship to food. Or just take drugs. That works too

Re: GLP-1 drugs: An economic disruptor? (2024)

#376

Post by cedws »

lm28469 wrote: post #277
cedws wrote: post #167

Earlier quoted context omitted.

Even so. Food can evoke the same neurochemical response as hard drugs or sex for some people. It is even more readily available than either of those things, and it is advertised and produced by multinational conglomerates with huge advertising budgets. They have the resources to maximise the attractiveness of their products and optimise the way they taste to be as pleasurable to eat as possible. Usually that means fi…

I have the same reasoning but the opposite conclusion, we should seriously reconsider our lifestyle choices, as a society, instead of just throwing a magic pill in the mix and closing our eyes on the fact that we're building a completely insane system in which humans are everything but thriving

Ok cool, let me know how you plan to do that.

Re: GLP-1 drugs: An economic disruptor? (2024)

#377

Post by hn_throwaway_99 »

appleorchard46 wrote: post #334

Obesity causes many health problems, but it's also a symptom - of our poor relationship with food, of the way American society is set up around instant gratification, of the predatory nature of food manufacturers. Though treating the symptom is undeniably good, it also lets the deeper problems that lead to it go unchecked, and my fear is that it will lead to novel problems down the line. How recreational drugs are be…

I agree with everything you've written, and I think your thoughts about Ozempic are spot on.

In the US, though, I don't mean to be super pessimistic but the problems are now so ingrained that I don't really see them improving for at least several generations. Stuff like:

1. Basically everywhere except for a few notable cities are organized around the car. Even if you wanted to walk places in a lot of towns it's near impossible or dangerous due to the road architecture. Fixing this now that it's built is an enormous challenge. I'll be long dead and gone before even a dent is made in it.

2. For decades we've been going in the wrong direction, and I don't see that changing anytime soon. I'm often shocked and saddened by how, well, "thick" high schoolers are these days. Like when I was a kid, there were certainly "fat kids", but it really wasn't that common. And we had a joke that when people went to college they would gain the "freshman 15" due to the all-you-can-eat dining hall plans. To me it looks like the freshman 15 now starts for high school freshman. And while I don't have kids, I've also heard others say how childhood has drastically changed since I was a kid. So much "hanging out", which used to be a physical activity, is now just done on phones. Except for organized sports, kids these days get much less "ad hoc" physical activity. High school is usually the thinnest/most fit a lot of people will be in their lives, and so I think we've condemned a ton of kids to a lifetime of obesity and health problems.

I'm all for changing our structural issues, but I'll take an imperfect solution now over something I don't think will come to pass for decades.

Re: GLP-1 drugs: An economic disruptor? (2024)

#378

Post by TylerE »

cj wrote: post #19

I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…

One thing this comment ignores is the very non-zero chance, which increases with dose and time on the drug, of developing gastropwresis. Gastropwresis will ruin your life to the point where you may never be hale to eat normal solid food ever again.

Re: GLP-1 drugs: An economic disruptor? (2024)

#379

Post by farts_mckensy »

thisisnotauser wrote: post #343
appleorchard46 wrote: post #334

Obesity causes many health problems, but it's also a symptom - of our poor relationship with food, of the way American society is set up around instant gratification, of the predatory nature of food manufacturers. Though treating the symptom is undeniably good, it also lets the deeper problems that lead to it go unchecked, and my fear is that it will lead to novel problems down the line. How recreational drugs are be…

The destructive behavior is overeating and this treatment eliminates the overeating. The problem is human beings are imperfect creatures. This drugs corrects the hormone imbalance that leads to overeating. It is fixing the actual problem. The idea that medical treatment makes us weaker is genuinely harmful nonsense on the order of claiming vaccines make us sick, and you should seriously reconsider your position here.

They're not saying medical treatment makes us weaker. Can you refute what they're saying without strawmanning them?

Re: GLP-1 drugs: An economic disruptor? (2024)

#380

Post by wakawaka28 »

glp1guide wrote: post #342
wakawaka28 wrote: post #270

Earlier quoted context omitted.

It will probably fuck up your body in ways that we can hardly imagine. Ozempic has been linked to lots of horrible side effects.

No it hasn’t— its well researched and the short to mid term (ish) side effects are well known: https://glp1.guide/tag/category-side-effects/

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