> Strontium-90 has better power-density per unit mass than Pu
The power density of Sr-90 fuel is 15% lower by mass than Pu-238 - 0.46kW/kg thermal compared to 0.54kW/kg thermal. You must have been looking at the wrong figures. Since the Sr-90 fuel rod doesn't get as hot as a Pu-238 fuel rod of the same size, energy conversion efficiency drops significantly and you need up to 100% more Sr-90 fuel (and consequently more shielding as well) to get the same power.
> Half-life is comparable.
A factor of 3x is not really comparable (87.7 vs 28.7 years).
> Safety is better: less gamma, no neutrons, no shielding needed.
Where did you get that from? Strontium-90 and its daughter product Yttrium-90 emit high-energy beta particles and thus give off high energy bremsstrahlung which requires heavy shielding. The BUP-500 battery (the largest RTG ever built, designed to provide 500W electric after 5 years; 1.8m³ in size and 3.6 metric tons in weight) used a tungsten alloy for shielding; its predecessors used depleted uranium...
Pu-238 on the other hand is pretty much exclusively an alpha emitter and has no short-lived daughter products (U-234 has a half-life of >200ka).
> Overprovisioning is needed in every case, and excess power has to be dealt with the same way.
Again, where did you get that from? A space mission is designed to a certain power spec and if you need your primary instruments for a 15 year mission, you plan your power such that after 15 years all primary instruments can still be powered. With Pu-238 that'd be about 75%-80% of the initial RTG capacity (some losses due to development time and efficiency losses from thermocouples are included).
Due to its properties, Sr-90 would require about 3x as much fuel just to make up for its shorter half-life in addition to the up to 100% increase in required fuel mass from its lower temperature.
Since it's a beta emitter, the additional radiation requires heavy shielding as well. So no, there's a pretty substantial difference there.
> Low cost to orbit means more fuel / more ∆V is practical to provide, thus much shorter transit times, translating to less up-front decay.
That's not how interplanetary missions work. Chemical rockets are incapable of providing enough delta-V to substantially shorten transit times to the outer solar system. If you want to do anything other than fly-by missions, more chemical fuel isn't going to help with that - you'd need nuclear or electric propulsion [1].
[1] https://www.esa.int/gsp/ACT/doc/PRO/ACT-RPR-PRO-ISTS2004-Plu...