OxyContin's 12-hour problem

The bar for prior restraint on public airwaves is much lower. We'd be much better off if drug marketing were relegated to the shady corners of the internet for advertising.

> Addicts are going to get fucked up on whatever they can find. If they can't find opiates or whatever, they're going to get fucked up on cough syrup, or booze or huffing paint or whatever.

While this is reminiscent of something Matt Dillon's "shameless dopefiend" character from Drugstore Cowboy said, I'm not sure if this is true.

There is another thread of addiction research that establishes the notion of "addiction as self-medication," in which users seek the drugs that work to alleviate their symptoms, be they physical or psychological. Anecdotally, I've experimented with a lot of substances, and opioids are the only class of compounds that I have sampled that work for me.

In addition, while it's certainly true that, if you attach two acetyl groups to morphine you end up with something 2-3 times more potent by weight, I wonder if people's conception of the "hardness" of drugs is somewhat artificial.

I've enjoyed the discussion we've had here and in the other thread as well- and I mean no disrespect, but I take it that you're not used to the streets (if i've missed the mark, i apologize). It sounds like that world is unfamiliar to you - which isn't a bad thing, but in that underworld people don't think the same way. It also sounds like you're someone who has never experienced withdrawal symptoms of a severe opiate addiction (which is definitely not a bad thing). Legality isn't stopping anyone. There is not a dopefiend on the planet who, given the opportunity, wouldn't do just about anything for a fix in dire straits. It is that bad, regardless of your place in life or social status. I don't know if you are taking into account how incredibly easy it is to go from "i'm getting these from a doctor, and have a prescription" to shooting dope in places you wouldn't come within miles of otherwise.

Price - It depends on location and other factors, but i can tell you from personal experience that as a user, as far as pure numbers go, heroin ends up being much cheaper than prescription pills (which are the most popular form of opiates). it was pretty close in price on either coast and the midwest, in big cities and smaller towns. (except Florida, surprise! pills are dirt cheap there and it's deadly. there are pharmacies on top of pharmacies on top of shady doctors offices in Florida, it's like goddamn Mexico. not an exaggeration). I've been out of the game for a while, but I hear through the grapevine there are recent shifts in the market as Govt. officials crack down on Docs who they perceive as writing too many scripts. This immediately takes a major source of Rx meds out of the game, which is the ideal opportunity for heroin dealers to move in - and as soon as that happens, on day 0, it's too late to fix in the current system we have in place in the US.

Availability for 'street drugs' right now isn't really an issue in my experience. Opiate addicts are a subset within a subset of drug addicts and they tend to flock together. An addict of many years on the streets can spot another addict (or a corner boy) easily, and they all know where to go to get it.

There is also quality control on the streets, it's messed up but it's true and works: If a dealer sells a new batch to a group of 5 users and 3 of them overdose word will get around that it's killer shit and then that's what all the other users WANT because they figure it's potent. I've seen dealers with Narcan nose injections on them at all times, specifically with the intention of saving a dope fiend's life when they OD just so he goes out and tells the other users it's good shit. Then he can either cut it to stretch it out and make more money, or continue giving out the goods to build loyal clientele.

The converse of that works as well, if you sell a faulty product then you become the LAST option on the addict's go-to list. The fact that someone who sells a faulty product intentionally is even still on the list at all is a testament to how fucked up opiate addiction is.

And I'm all for legalizing, controlling, and even taxing weed (for recreation and ESPECIALLY medicinally) -- but if heroin ever becomes as easy to get as alcohol.... man, unless someone discovers how to drastically change how opiate receptors in your brain work, that would be the modern day equivalent to the zombie apocalypse. We'd be doomed, everyone.

> how do you find out about new stuff then?

"Instead of relying on marketing, I rely on information from good, well performed randomised controlled studies published in reputable peer reviewed journals ( I like the NEJM ) and on meta-analyses of these. I view the results of these through a filter of scepticism, cynicism, pragmatism and a modicum of hope."

> how could they get you to read about it?

I'd assume by performing a sensible clinical trial that proves its efficacy beyond a reasonable doubt.

Advertising is how you're sold things whether or not you need them. It is not how you learn about what's best for your patient. There are other avenues of information that aren't tainted by the motivation to sell a product despite the consequences.

No, it's commercial speech. The FDA already regulates what they can say in drug advertisements. There's not really a legal issue there.