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Trials begin on lozenge that rebuilds tooth enamel

dental.washington.edu

331–340 of 364 posts

Re: Trials begin on lozenge that rebuilds tooth enamel

#331

Earlier quoted context omitted.

Amazon is a modern day Dutch East India Company. There’s no reason for them not to be predatory, given that they wield so much power.

Or British East India Company. Not like either wasn't predatory back in its heyday.

Good point, you’re right on that.

Re: Trials begin on lozenge that rebuilds tooth enamel

#332
post #77

Earlier quoted context omitted.

I used to drink that much coffee. I got an espresso machine and started making americanos instead now I’m good with one cup a day. I don’t know what it is, clearly the caffeine is either higher or more bioavailabile or something, but it just sates my appetite for coffee. (Actually i started making cappucinos first and stopped when i started putting on weight from them lol)

I don't think you're using units that could allow anyone to detect whether it's caffeine quantity or bioavailability that's at play. It depends on how you dose your espresso and drip coffee. I don't drink espresso but I think people are dosing something like 20 grams per shot, whereas for pourover they're dosing 18 grams of water per gram of coffee. For a standard "coffee cup" (which is 5 ounces of water that results…

Maybe I'm being a bit cheeky but for me, the stochastic caffeination aspect is part of the fun.

Re: Trials begin on lozenge that rebuilds tooth enamel

#333

Assuming this works, isn't this pretty much game over for dentists? I'm aware that dentists do more than fillings, but it seems like there would be a serious contraction, even if this costed something like $1000 a tooth after insurance. That being said, even if this worked, it's not like it's instant, so you still have to be careful with your teeth. I wonder how this differs from novamin, which supposedly does the sa…

This study of Novamin concludes: > Review shows that Novamin has significantly less clinical evidence to prove its effectiveness as a remineralization agent in treating both carious and non-carious lesion. Hence, better designed clinical trials should be carried out in the future before definitive recommendations can be made. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068624/

This is the unfortunate truth of dentistry: things that work in the clinic and lab don't translate well to everyday life.

Water flossers are advertised as being as effective as floss. However, it turns out studies on floss haven't borne out either.

Re: Trials begin on lozenge that rebuilds tooth enamel

#334

Earlier quoted context omitted.

As of a few years ago there's a similar FDA approved ingredient available in the US as BioMin. It works well for me and is cheaper than importing NovaMin.

Biomin also claims that their particles are smaller and therefore more effective at mineralization than Novamin. Another option for leveling up on toothpaste is using those that contain micronized hydroxyapatite. Options here are Carifree or the Japanese brand Apagard available on eBay or Amazon. Biomin’s formula is proprietary but it might contain hydroxyapatite in part. I stopped randomly getting cavities after usi…

HAP, available in Japan since 1970.

wow, just found this where they compared HAP to fluoride and found no difference: https://www.nature.com/articles/s41405-019-0026-8

I have novamin. I think it makes my teeth feel different. May be placebo.

A lot of people swear by HAP, novamin, etc. I suspect it all comes down to increased oral care and diligence though!

Re: Trials begin on lozenge that rebuilds tooth enamel

#335
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

I had 1 cavity in my decades and I had really awful habits. All of my teeth were sealed in youth.

I too have bruxism that is wearing down some molars severely. My grandfather wore his teeth down to about nothing.

My dentist suggested I get Invisalign for tooth crowding, veneers for small canines, and a mouth guard I can't tolerate at present). If had a workable mouth guard, I would do this lozenge thing. I feel sensation in my teeth and gums constantly.

I never did whitening because I always thought the risks were too great.

Re: Trials begin on lozenge that rebuilds tooth enamel

#336
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

Botox.. hmm. Interesting.

I chipped / broke half of a crowded-out front tooth one night a month or so ago. My teeth sometimes chatter on their own at night.

My jaw is compact and massively internally-hypertrophic (reinforced) from a lifetime of bruxism. Also, masseters are jacked, teeth roots are extremely long, and my neck muscles are hypertrophic (no neck) too. I wonder if this is an evolutionary adaptation of a "fighter" body plan.

Re: Trials begin on lozenge that rebuilds tooth enamel

#337
post #235

Earlier quoted context omitted.

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

Back problems, bruxism, migraines - have you had yourself tested for some bacterial infection like e.g. lyme or bartonella? Just to have that excluded before treating symptoms. I've had all of this for years (more like decades) plus different additional symptoms and got diagnosed last year. The ongoing treatment is not for the faint of heart but symptoms are on the retreat since. PS: I've grown up in rural Germany an…

I've had bruxism my entire life. Headaches, TMJ, and jaw pain are what I've experienced.

Most people have back problems, so that could just be concomitant.

I used to live in an area with endemic Lyme disease, but contracting that would've presented all kind of other horrible symptoms.

I also have SCDS, likely from pushing too forcefully on the loo, loud noises, air pressure extreme changes, high blood pressure/swings, and congenital thinness as confirmed on CT. The fix require a middle fossa craniotomy approach.

Re: Trials begin on lozenge that rebuilds tooth enamel

#338
post #259

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What other bacterial infections could cause these symptoms aside from lyme and bartonella? Would such an infection be able to explain chronic symptoms over a 1-2 year period?

My MD offers lab tests for Chlamydia, Bartonella, different strains of Borellia, Yersinia, Ehrlichia amongst others, she also offers tests for HPV and Mono. To be honest: I have no clue what is causing which exact symptom, it's also often the immune response / inflammation that's the reason for the pain and other problems. Edit: forgot to answer your question. yes, in my case it was episodes of joint pain, neck stiff…

Numb fingers can be from distal neuropathy. Pin and needles or reduced sensation. I have reduced sensation almost everywhere.

Re: Trials begin on lozenge that rebuilds tooth enamel

#339
post #299

Earlier quoted context omitted.

Thanks. What kind of specialist is suggested for such a bacterial infection? Immunologist?

My general practitioner who is also an internist was overwhelmed ("deal with it, you're getting older" diagnosed only psychosomatic reasons etc). A friend of mine suggested an MD who specializes in such infections, I later changed to a Doc nearer to where I live. Got the address from Deutsche Borreliose Gesellschaft, a german registry for lyme.

MDs who get arrogant, lazy, or gaslight patients into thinking they're "crazy" are no longer practicing medicine but are rationing care, sticking their heads in the sand, and hands in the air.

One ENT told me I had "allergies" when I said I could hear my left eye move in my head and he pretended he didn't find an Weber test extreme left lateralization. Another two ENTs found I have repairable SCDS as confirmed by high resolution CT and audiological testing.

Doctors who don't listen to you or BS you cannot be trusted with your life. Dump them and don't feel bad about it because they gave up on you first. There is no reward for loyalty. It's only your life.

Re: Trials begin on lozenge that rebuilds tooth enamel

#340
post #311
post #274

Earlier quoted context omitted.

> multi-million dollar business That is not a business, just an idea. The value of ideas (unproven, unimplemented) is ZERO. The fact that someone was willing to pay $100k for it is absolutely amazing and a huge service to the society.

This is absolutely wrong. Especially when the formulation of the idea depends on extremely advanced knowledge of the topic.

Prove me wrong. Try selling an idea and let us know how much money you got for it.
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