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Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

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Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#331

Post by roystonvassey »

scotty79 wrote: post #322
eni wrote: post #272

Earlier quoted context omitted.

it's not turmeric, it's curcumin, which is about 2% of turmeric by mass (so, you'd need to eat ~4.5g turmeric daily to match study doses) Typical Indian cooking uses turmeric in pretty much everything. I wouldn't be surprised if daily consumption of turmeric is very close to the figures you mentioned.

Also: http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year... > Worldwide, esophageal cancer is the eighth most common cancer [...]. In India, it is the fourth most common cause of cancer-related deaths. Granted it's probably due to alcohol and tobacco but curry probably won't save you from cancer.

This is spurious correlation at its best. Terrible science at it is worst.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#332

Post by hanklazard »

pytonslange wrote: post #288
hannob wrote: post #152

Small study, probably not preregistered (didn't find anything about it in the description). Likely Publication Bias or p-hacking. I'm starting to get interested when it's been independently replicated.

It was registered as a clinical trial ( https://clinicaltrials.gov/ct2/show/NCT01383161?term=NCT0138... ). If you are concerned about p-hacking and replicability, what should worry you is that the outcome measures posted during registration are rather vague, i.e. ".. show less evidence of cognitive decline (as measured with neuropsychological assessments)" At baseline, they performed an extensive neuropsychologist te…

Excellent point. Outcome measures should have been more clearly defined in pre-registration. As it was done, p-hacking and selective reporting were still possible.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#333

Post by roganp »

vanderZwan wrote: post #330
closed wrote: post #323

Earlier quoted context omitted.

When a small sample size produces a big effect, it does not mean you can be more confident in the effect! All things equal, you'd expect confidence intervals / credible regions to be very large. Another way to say this, is that since the measurement error is large, you expect spurious findings that result from something like p-hacking to be large (they have to be to be significant).

What annoys me as a someone not trained in statistics is that these discussions are always abstract in-principle arguments about what proper statistics should be like. Meanwhile, we have a real paper with real p-values , why not discuss the validity of that? > SRT Consistent Long-Term Retrieval improved with curcumin (ES = 0.63, p = 0.002) but not with placebo (ES = 0.06, p = 0.8; between-group: ES = 0.68, p = 0.05).…

Here is the problem: If there is an actual large effect size, then you can detect this in small samples. However, the opposite is not true. In a small sample, spurious large effects are MORE likely, not less likely (outliers have a greater impact in a small sample). See: http://andrewgelman.com/2017/08/16/also-holding-back-progres...

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#334

Post by CuriouslyC »

DiabloD3 wrote: post #113
iambateman wrote: post #106

Couple questions... I’ve read that Bromelain (from Pineapples) can help with sinus inflammation. Is there any indication about Turmeric helping with sinus inflammation? Silly question...is “inflammation” one thing? As in do brain inflammation and sinus inflammation go together? Finally, any resources on reducing inflammation generally?

Reducing inflammation is surprisingly easy, which is why most people just don't do it (they want an expensive magic pill instead of just using methods that actually work). First, remove the largest inflammatory things from your diet: no grains, no refined sugars, no processed meat, no dairy (unless it is truly fermented, such as hard cheeses and true greek yogurt), and no legumes. Second, walk about 2 miles a day (at…

Not only is there strong anecdotal evidence for legume consumption being healthy given the prevalence of legumes in blue zone diets, there is also a mountain of scientific evidence indicating the short chain fatty acids produced by fermentation of legume polysaccharides provides a large number of health benefits. Additionally, low fat non-greek yogurt consumption has been linked to a variety of positive health outcomes. Finally, moderate grain consumption is alright assuming you're physically active and the grains are unrefined. If you spend more time studying the scientific literature you will see that the paleo diet is mostly trendy bullshit.

In terms of training, high repetition weight training is absolutely beneficial, while being much easier to recover from than lower rep weight training. While it shouldn't make up the majority of your training, it is worth making a significant portion of your total training volume.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#335

Post by maxxxxx »

Flow wrote: post #266
maxxxxx wrote: post #203

Earlier quoted context omitted.

Turmeric has helped me quite a bit with my inflamed joints after learning about it at a yoga ashram. Now I cook a lot with it. What i have noticed though is that supplements do nothing for me. I only feel a difference when it's fresh powder or even better ground from a root. I have done several experiments where I stopped taking it. Every time my joints got worse and then better after resuming cooking with Turmeric.…

It common among men with low testosterone to have aching joints. Have you checked your levels? Also funny that some men on TRT take turmeric(with some black pepper) to lessen the amount of estrogen converted from testosterone.

Actually I checked my levels a few years ago and they in the lower range of normal. The doctor said it's fine but I was wondering about that. My recovery time from injuries and workout also has increased a lot. It's probably part of aging but testosterone could play a role too.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#336

Post by neltnerb »

bildung wrote: post #296
geezerjay wrote: post #295

Earlier quoted context omitted.

Appeals to authority, such as those you've made, are worthless. The motto of the Royal Academy of Sciences is quite literally "take no one's word for it". If you wish to blindly swallow assertions made by people with academic titles, perhaps you should start to listen to those who advise against it.

An appeal to authority is perfectly reasonable if the person in question is actually an authority in the topic discussed. The logic fallacy you probably meant is about appeals to authority in cases where the authority is in another domain.

Yeah, if I'm going to be wrong I'd rather be wrong alongside a bunch of people who are way more qualified than me to guess. What's the P-value on trust in expert advice improving outcomes? For every case where the "x was wrong" there are 1000 non-controversial cases where x was right.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#337

Post by neltnerb »

blacksmith_tb wrote: post #43
adamc wrote: post #27

Earlier quoted context omitted.

How do you take it?

I buy bulk 95% powder, pop a piperine tablet, and dump 3/4 tsp of powder in my mouth - eating something with it to get it down. I experimented with mixing it with various things, but it's hydrophobic and stains everything bright yellow, so the quicker the better. I was mostly interested in the anti-inflammatory properties, my family is full of arthritis, and between climbing and typing, I started noticing some in my…

95% what? curcumin or turmeric extract? I ask because I've ordered plant extracts on alibaba and did GC analysis. From the labeling it is pretty difficult to tell which you're getting.

One may be very high purity curcumin while the other is curcumin alongside all the other components extracted.

This, for instance:

https://purebulk.com/curcumin-turmeric-extract-powder/

seems like what you probably would find with a simple search, and there's not even a mention of the actual curcumin concentration.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#338

Post by luka-birsa »

gopalv wrote: post #252
luka-birsa wrote: post #216

Earlier quoted context omitted.

Not sure if high natural background radiation really means more cancer. I tried searching but I cant find a study where apartment builings in Japan were inadvertently built using steel laced with radioactive elements. People (10000) were living in them for decades. Statistical analysis on them showed lower affinity for cancer related deaseses.

> inadvertently built using steel laced with radioactive elements. > Statistical analysis on them showed lower affinity for cancer Radiation Hormesis might be real (I hope so), but if it gets through drywall, it would be a different form of radioactivity to the one I grew up around. Alpha decay needs just a simple sheet of paper (or dead skin cells) to stop the radiation, but it messes with DNA if you happen to eat i…

Found the study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477708/

It wasn't Japan, but Taiwan.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#339

Post by YeGoblynQueenne »

dumbneurologist wrote: post #314
YeGoblynQueenne wrote: post #250

From the Wikipedia page on Curcumin (section Research): In vitro, curcumin exhibits numerous interference properties which may lead to misinterpretation of results.[3][6][20] Although curcumin has been assessed in numerous laboratory and clinical studies, it has no medical uses established by well-designed clinical research.[21] According to a 2017 review of over 120 studies, curcumin has not been successful in any c…

None of your criticisms from wikipedia pertain to this publication. The paragraph is essentially making the argument that a randomized, double blind (DB), placebo controlled (PC) clinical trial (RCT) is unlikely to show that curcurmin is effective. yet, the published article is exactly that, and shows a statistically measurable impact on a clinically meaningful endpoint: a direct refutation of the paragraph. the fact…

>> None of your criticisms from wikipedia pertain to this publication. The paragraph is essentially making the argument that a randomized, double blind (DB), placebo controlled (PC) clinical trial (RCT) is unlikely to show that curcurmin is effective. yet, the published article is exactly that, and shows a statistically measurable impact on a clinically meaningful endpoint: a direct refutation of the paragraph.

I think, if there are solid reasons to believe that studies on curcumin will not turn up any useful results and then a study finds results it calls significant, the chances are that either that study is not designed very well, or its results are not significant, despite the claims of the authors.

Apologies in advance for the controversial example, but this reminds me of the controversy about Daryl Bem's parapsychology research a few years ago- the author claimed his study was methodologically unassailable, but of course he was making an absurd claim (essentially, that people can receive information from the future via ESP).

Edit: removed cruft.

Re: Curry spice turmeric boosts memory by nearly 30%, eases depression, study finds

#340

Post by vanderZwan »

roganp wrote: post #333
vanderZwan wrote: post #330

Earlier quoted context omitted.

What annoys me as a someone not trained in statistics is that these discussions are always abstract in-principle arguments about what proper statistics should be like. Meanwhile, we have a real paper with real p-values , why not discuss the validity of that? > SRT Consistent Long-Term Retrieval improved with curcumin (ES = 0.63, p = 0.002) but not with placebo (ES = 0.06, p = 0.8; between-group: ES = 0.68, p = 0.05).…

Here is the problem: If there is an actual large effect size, then you can detect this in small samples. However, the opposite is not true. In a small sample, spurious large effects are MORE likely, not less likely (outliers have a greater impact in a small sample). See: http://andrewgelman.com/2017/08/16/also-holding-back-progres...

Thank you, that is an explanation that I can actually apply to this result.
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