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Current RNA vaccines protect against worrying coronavirus variants

nature.com

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Re: Current RNA vaccines protect against worrying coronavirus variants

#321

Post by chitowneats »

ptaipale wrote: post #319
chitowneats wrote: post #318

Earlier quoted context omitted.

Including after vaccination? If no, why is that different than infection?

No, not including after vaccination. When people speak about pre-existing immunity, it's most of the time covid deniers saying there "natural" immunity and vaccines are useless or harmful. (Of course there is also valid discussion of pre-existing immunity, but the more nuanced messages are not as common.)

Vaccine advocates like yourself can never explain why infection doesn't imply immunity while vaccines do.

Sinovac, the Chinese vaccine, is only 50% effective. Pfizer and Moderna are much more effective. J&J is somewhere in between. This is widely accepted but no one seems to ever ask: if I was sick a month ago, where does it fall in that scale?

The point of vaccines is to give your immune system a good enough idea of the pathogen, so that your body produces antibodies. Actually contracting the disease does the same thing, unsurprisingly.

So the question is how effective is natural infection of COVID-19 at preventing future infection? Surely it's better than Sinovac, a coin flip. No? Do you have any scholarship about this I can look at?

Re: Current RNA vaccines protect against worrying coronavirus variants

#322

Post by chitowneats »

maxerickson wrote: post #277
chitowneats wrote: post #242

Earlier quoted context omitted.

It's also riskier for most folks to drive a car than to catch Covid. I agree that people should look at their specific case and do honest risk/benefit analysis. Most of what I've seen, however, feels more like herd mentality behavior based on one's political leanings. Or people feeling they genuinely don't have a choice, given impending requirements and restrictions from their local governments and employers. Edit: n…

I estimated that my risk from getting infected was similar to the lifetime risk of driving. If I could get a shot that protected me from car accidents, I'd do that too.

The shot doesn't last a lifetime. You'll need two shots a year, at minimum. Third and fourth booster shots needed in the fall are already being discussed.

Re: Current RNA vaccines protect against worrying coronavirus variants

#323

Post by DiogenesKynikos »

TedPetrou wrote: post #316
DiogenesKynikos wrote: post #220

Earlier quoted context omitted.

The AstraZeneca and Sinopharm vaccines have similar efficacy: they're about 80% effective at preventing symptoms. They're even more effective at preventing serious illness and death. The Seychelles is still 40% unvaccinated. Even people who are vaccinated have some chance of getting infected, though if they get infected, their chance of showing symptoms is lower, and their chance of ending up in the hospital is much…

Seychelles has vaccinated 68.5k of its 98.5k population. [Around 25% of its total population]( https://en.wikipedia.org/wiki/Demographics_of_Seychelles ) are 0-17, so maybe 75k max 18+. Over 90% of adults are vaccinated and less than 7k remain unvaccinated. Seychelles just reported 1800 cases for the last week or 1.8% of its total population. This equates to 6 million cases in the US or more than 800k per day, a numb…

Unless you calculate an actual efficacy, the above numbers are not very informative. What efficacy is implied by the numbers?

Re: Current RNA vaccines protect against worrying coronavirus variants

#324

Post by ptaipale »

chitowneats wrote: post #321
ptaipale wrote: post #319

Earlier quoted context omitted.

No, not including after vaccination. When people speak about pre-existing immunity, it's most of the time covid deniers saying there "natural" immunity and vaccines are useless or harmful. (Of course there is also valid discussion of pre-existing immunity, but the more nuanced messages are not as common.)

Vaccine advocates like yourself can never explain why infection doesn't imply immunity while vaccines do. Sinovac, the Chinese vaccine, is only 50% effective. Pfizer and Moderna are much more effective. J&J is somewhere in between. This is widely accepted but no one seems to ever ask: if I was sick a month ago, where does it fall in that scale? The point of vaccines is to give your immune system a good enough idea of…

What? Of course infection induces immunity in case of covid, about on par with mRNA vaccines like Pfizer and Moderna.

https://www.nih.gov/news-events/nih-research-matters/lasting...

You don't have similar immunity efficacy studies for actual covid as hou have for vaccines, because infecting people on purpose would be unethical.

Note that your wording "coin flip" isn't right for Sinovac, either. 50 % efficacy is not huge but it is still beneficial on population level.

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