Earlier quoted context omitted.
Certainly they can. What's forcing you to publish in nature? Just like... don't. If someone down the line is judging you based on what journal your work ended up in and not the quality of the work... well you probably don't want to work with them anyway
Are you in academia? Not trying to be snarky here -- genuinely want to know your perspective. As an outsider, everything I know about it leads me to believe that academia is so competitive that you really can't afford to just "not publish in top journals" and be picky about who you work with/what offers you take.
An academia that cares about journal over quality of work isn't really one I want to be a part of, so either way I'll be happy with the outcome.