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What Ozempic does to the gut-brain axis

psychologytoday.com

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Re: What Ozempic does to the gut-brain axis

#311

Post by ab5tract »

ElProlactin wrote: post #230
wpm wrote: post #21

Earlier quoted context omitted.

Why not? People take depression meds, blood pressure meds, all kinds of meds for their whole life. I'll be on omeprazole for reflux my whole life. It doesn't solve the underlying problem of my gut being prone to overpumping acid into my stomach. So omeprazole is problematic? The underlying issue is being treated, it's treated by taking the drug. It works. It's doing its job. I'd be curious as to how you came to this…

> People take depression meds, blood pressure meds, all kinds of meds for their whole life. And a lot of these medications have side effects that can affect quality of life negatively in other ways. That doesn't mean they're not helpful, or shouldn't be taken. But the "no free lunch" rule usually applies, sometimes to a noticeable degree.

And? It’s not like those of us on lifetime-prescriptions have any real choice in the matter.

Oh, there’s consequences? One of those is an almost universal weight gain measured in the dozens of kilos? You want help with that?

Sorry, it’s against Calvinist/puritan morality to help you with that by providing a medicine to counteract that. You need to do it the hard way (regardless of the statistics that show you will just be obese now until you die thanks to the meds which, I maintain, that you must take).

Re: What Ozempic does to the gut-brain axis

#313

Post by weregiraffe »

faangguyindia wrote: post #253
genericresponse wrote: post #239

Earlier quoted context omitted.

Obesity is widely regarded as a chronic disease that includes the interaction of genetic and other factors with behavioral factors. The unbelievably low success rate of diet and exercise programs for long-term weight reduction is widely documented and quite consistent with the earlier poster's experience.

>The unbelievably low success rate of diet and exercise programs for long-term weight reduction is widely documented and quite consistent with the earlier poster's experience. where is your data from? what protocol did they follow?

The problem is the difficulty in following any protocol.

Re: What Ozempic does to the gut-brain axis

#315

Post by toasterlovin »

faangguyindia wrote: post #249
toast0 wrote: post #203

Earlier quoted context omitted.

Plenty of people can take this intelectual knowledge and turn it into eating behaviors that work for them. But this intelectual knowledge doesn't really help if your body is telling you it's hungry all the time and it's hard not to eat something . Better choices can help, because different calories deliver different satiety; but some people don't get much satiety no matter what they eat. Calories in vs calories out i…

>But this intelectual knowledge doesn't really help if your body is telling you it's hungry all the time and it's hard not to eat something. Better choices can help, because different calories deliver different satiety; but some people don't get much satiety no matter what they eat. Maybe try to figure out why you’re feeling hungry. Is it because you’re running a 1000 kcal deficit? Can your body really tell whether y…

> Maybe try to figure out why you’re feeling hungry.

For a lot of people, the reason they feel hungry is because the way their brain works is that they feel better when they feel full and their life sucks for some reason, so they want to feel better. Hence overeating. It’s entirely a psychological issue for a person like this. Counting calories is not going to help them. In fact, them even being able to maintain a calorie counting regime is downstream of resolving their anxiety/stress/depression. In other words, diet and exercise are not the beginning in the causal chain required for them to lose weight.

And you’re getting absolutely no traction in this thread because you’re completely oblivious to this. Which is common for someone for whom diet and exercise is easy to control.

Re: What Ozempic does to the gut-brain axis

#316

Post by faangguyindia »

kube-system wrote: post #286
faangguyindia wrote: post #257

Earlier quoted context omitted.

deficit = tdee - intake Active life = higher TDEE which means you can eat more food while still maintaining same deficit.

Exercise also stimulates digestion and triggers a hunger response in many people. This is why exercise without diet often fails to result in weight loss.

People overestimate calorie burn from exercise.

For example, a lifting session may burn 200-300kcal and then they'd think they've burned a lot, so they will end up eating 500kcal back.

so as a result there is no deficit there.

Re: What Ozempic does to the gut-brain axis

#317

Post by sakopov »

joshuamcginnis wrote: post #16

Studies show almost all subjects regained the weight and reversed gains within 2 years. This means underlying issues (e.g., food addiction) aren't being addressed. Short of changing habits, the only maintenance solution is lifelong drug use and that doesn't sit well with me.

Does loss of muscle mass, commonly associated with Ozempic weight loss, become an issue after regaining the weight? Can it result in proportionally more fat at the same body weight as before if exercise wasn't part of the regiment?

Re: What Ozempic does to the gut-brain axis

#318

Post by kube-system »

faangguyindia wrote: post #316
kube-system wrote: post #286

Earlier quoted context omitted.

Exercise also stimulates digestion and triggers a hunger response in many people. This is why exercise without diet often fails to result in weight loss.

People overestimate calorie burn from exercise. For example, a lifting session may burn 200-300kcal and then they'd think they've burned a lot, so they will end up eating 500kcal back. so as a result there is no deficit there.

Exercise typically doesn’t cause people to eat because they are confused about estimating caloric expenditure, it causes them to eat by inducing hunger.

Even people who track their calories perfectly often eat when hungry because it is the most basic of human instincts and our brains and bodies are wired to respond accordingly.

Re: What Ozempic does to the gut-brain axis

#319

Post by s1artibartfast »

faangguyindia wrote: post #275
mycall wrote: post #265

Earlier quoted context omitted.

People can get fat by eating too much healthy food.

true but you'll struggle getting tons of calories out of whole foods. This is why mass gainers are popular, underweight people find it hard to gain weight so they dirty bulking using fast food which is often calorie dense. Eating healthy food alone isn't solution, you need to make your life active as well.

This has never been my problem. I can easily eat 5k calories of whole foods
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