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Creatine raises brain energy levels and slows cognitive decline: study
311–320 of 395 posts
Re: Creatine raises brain energy levels and slows cognitive decline: study
#312Earlier quoted context omitted.
The entire point is that >10G is justified if you're going for cognitive effects. For muscles you don't need to go above 5G. For brain, >15G.
For now there are zero studies that I know of that support this. The only ones are for sleep deprived.
There are a number of studies on the topic of varying quality but I think that's besides the point.
> It’s called a loading phase
This is not about a loading phase. "It's called a loading phase" indicates that the reason you would take high doses is for the muscular saturation that some people think is required. You're right that you can absolutely skip the loading phase, but that's not the point. The point is that you would take the higher dose for the cognitive effects.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#313Earlier quoted context omitted.
This is a myth, its not bad for your kidneys. The reason this gets spread is because you will have higher levels of creatine in your urine if your Doctor tests your urine for kidney function, which indicates kidney disease. However, If you reveal to that doctor that you're supplementing Creatine it will not be concern them.
Careful. Creatine metabolizes into creatinine which is major indicator of kidney function because not being able to clear creatinine means your kidneys aren’t working. Adding more creatinine to your system decreases your ability to clear it leading to fatigue, edema, high blood pressure etc. So it isn’t bad for your kidneys: it is bad for everything else.
Creatinine can be an indicator that your kidneys are not working well. It's a cheap red flag that can be screened for in a common blood test. But if heightened creatinine is a result of one's creatine supplementation, then there are none of the downsides associated with kidney disease.
Creatinine itself doesn't cause fatigue, edema, or high blood pressure. Kidney disease does.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#314no net study so what is this shilling
Re: Creatine raises brain energy levels and slows cognitive decline: study
#315Direct link to the study: https://jpbs.hapres.com/htmls/JPBS_1766_Detail.html I wanted to check the dosages they used. Looks like the review includes studies ranging from 5g/day to 20-25g/day. (Typical dosage you'll see for daily use is 5 grams)
>CONFLICTS OF INTEREST
DC has conducted industry-sponsored research involving creatine supplementation and received creatine donations for scientific studies and travel support and speaking honoraria for presentations involving creatine supplementation at scientific conferences and on social media. In addition, DC serves on the Scientific Advisory Board for Alzchem and Create (companies that manufacture creatine products) and as an expert witness/consultant in legal cases involving creatine supplementation. NF declares no conflicts of interest
A nice unbiased study, I may as well ask Exon Mobil for their opinion on climate change at this point
Re: Creatine raises brain energy levels and slows cognitive decline: study
#316Earlier quoted context omitted.
Long term studies haven't shown any harm. I've taken 30g a day for well over a year now for both the physical performance and the cognitive benefits. I had brain fog following a bad COVID infection which this has helped with. My family also has a history of Alzheimer's and dementia (both sides), I figure it can't hurt. The only side effects I've encountered have been mild GI discomfort, and that only rarely (mostly w…
30g? That seems like a lot - isn’t the standard dose 5g? Did you build up incrementally and find that to be the best?
It is definitely more than the standard dose. I was already taking 5g for weightlifting purposes. After some of the studies suggesting mental benefits I titrated my dose up to 30g (the high end of the studies). Just added an additional 5g per week until I hit 30. I add it in powder form to my daily protein shake-- usually in the morning. While it could be a placebo, I personally feel there's a noticeable difference. I buy in bulk so it ends up being less than $.90 a day to dose at this level. It's an extremely cheap supplement.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#317I don't hate AI but AI writing is SO boring. Not worth suffering through to read the article.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#318Earlier quoted context omitted.
I hear about tech bros taking creatine these days with the tone of voice that they use to talk about microdosing. So I can’t imagine it having zero effect. What I worry about more is that it has more to do with fixing a deficiency. That being deficient in creatine causes a cognitive loss more than supplementing causes a boost.
As someone who's microdosed (though mostly normal-dosed and occasionally megadosed) in the distant past, the whole microdosing fad was equal parts entertaining and baffling. Anecdotal, but from all people I know that has taken psychedelics, only one doesn't find it to be a waste.
Maybe a better analogy would have been the Balmer curve. I wasn’t trying to imply psychedelics are unhelpful, just that we should be careful of suggesting coding productivity gains while on them.
Also IMO, the Balmer peak is a stronger effect than creatine.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#319Earlier quoted context omitted.
> searching my spreadsheet What does this mean?
I keep a spreadsheet about my health, blood work, any supplements I take, how they make me feel etc. The summary would be that I take zero supplements now haha. I have tried so so many.
Any chance you'd be willing to share a template of your spreadsheet?
Re: Creatine raises brain energy levels and slows cognitive decline: study
#320The article made up the claim it’s not from the paper itself. There was some improvement in cognitive scores, but no placebo group. Without a placebo group, there are a lot of explanations for the data.
>> Recently, a pilot study (single-arm) by Smith et al., recruited 20 patients (73 years of age) with AD and provided them with 20 grams/day of CrM for 8 weeks [20]. Serum creatine levels were increased at weeks 4 and 8 (p Yeah 20 patients is not a lot. I'm inferring this is a pre-post test. However some of those p-values are pretty good (.001 on reading and and sorting). Very promising pilot study but not conclusive…
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