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GLP-1 drugs: An economic disruptor? (2024)

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Re: GLP-1 drugs: An economic disruptor? (2024)

#311

Post by no_wizard »

Henchman21 wrote: post #291
no_wizard wrote: post #276

Earlier quoted context omitted.

I’m not going to lie all this sounds like heaven to me. I absolutely hate the way my appetite works. I have a genuine dysfunction with food. It goes back as far as I can remember. My cravings never stop, even after being satiated. It’s an endless cycle of weight gain then loss then gain as my willpower fluctuates for a variety of reasons. My insurance only recently started to cover these weight loss drugs, and I have…

I'm a few months into this drug as well, and I have to say, it doesn't offer control . What it offers is a lack of cravings & appetite . That is different, remarkably so. Control would mean I might still feel hungry. Ever. Or that I could decide to eat heavily at one meal, but I don't and as long as I take the drugs, I won't. That doesn't feel like control, it feels like I've had something removed. I guess it's a mat…

The difference here may simply be in how our mental health relates to food.

It sounds to me like it brings you enjoyment you miss. I respect that.

Food for me isn’t that. The lack of cravings and appetite means I would be firmly in the drivers seat with it. It means I can eat exactly the amount I’m suppose to and not feel like I must have more

Re: GLP-1 drugs: An economic disruptor? (2024)

#312

Post by hombre_fatal »

crazygringo wrote: post #267
otterley wrote: post #266

Earlier quoted context omitted.

I don’t know if it’s the nature of the products themselves, or if it’s because they’re vastly cheaper and more accessible. There’s a natural limit to the number of cookies to be had from Grandma before she says “that’s enough,” vs being able to get 64 at the local market anytime you want for a pittance.

See, now we're talking. That's my point. It's got nothing to with supposed "manipulation" of ingredients. It's about other stuff -- whether it's price or accessibility or someone telling you "that's enough".

Yeah, I agree. People really seem desperate to believe it all comes down to boogeyman adulterants, but it's a huge red herring and completely unnecessary for ending up with a culture of junk food, obesity, and calorie surplus.

Drop dough into frying oil and then roll it in powdered sugar.

Drop potato slices into frying oil and then salt them.

You don't need boogeyman R&D chemicals to make food that you can't stop eating. What changed is the accessibility of these things. You can go to 7-11 and buy thousands of calories of packaged donuts for dollars. Combined with there only being junk food in US quickmarts compared to, say, cheap bento boxes in Japanese 7-11.

Re: GLP-1 drugs: An economic disruptor? (2024)

#313

Post by cyberax »

willis936 wrote: post #49
saurik wrote: post #36

Earlier quoted context omitted.

> Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month... So they are going to force you onto a higher dose?!

Yes, up to 15 mg. Maintenance levels at 5, 10, and 15. If you cannot tolerate a maintenance level you can still get it, but insurance will not cover it ($1000/mo rather than $15/mo.) This is not an unreasonable situation. https://www.goodrx.com/zepbound/dosage

If you want lower dosage, then there's a simple trick: just use less frequent injections. For example, try one in 10 days instead of 1 every week. It will result in lower steady-state GLP-1 levels.

Re: GLP-1 drugs: An economic disruptor? (2024)

#314

Post by temptemptemp111 »

cj wrote: post #19

I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…

[dead]

Re: GLP-1 drugs: An economic disruptor? (2024)

#316

Post by Judgmentality »

dang wrote: post #287
Judgmentality wrote: post #224

Earlier quoted context omitted.

I asked a question and he ignored it. I asked it again and he answered it. What you call haranguing I call a conversation.

Your comments come across as more aggressive than perhaps you intend them to. We've had to ask you similar things before. Telling someone that their spending is "fucking egregious" and "who knows what else you didn't mention", would land with most people as quite a provocation. The fact that cj replied courteously says something good about cj, but your comment broke the site guidelines and we need you not to do that.…

You're right. I was being a dick.

Re: GLP-1 drugs: An economic disruptor? (2024)

#318

Post by derkster »

willis936 wrote: post #64
aeturnum wrote: post #54

Earlier quoted context omitted.

> Yes well your PCP / pharmacist should not have prescribed you an appetite suppressant when you have below average body fat %. Why do you think this? I agree that people who have associated risk factors should be prioritized, but if there's enough for everyone why wouldn't we give it to anyone who wants it?

Because anorexia exists it would do harm to completely unregulate access to appetite suppressants. Someone should be looking out for people who would willingly wither away.

Putting Ozempic over the counter at a local pharmacy would be more than enough to keep people from wasting away, the same thing they do with asthma medication. In 2025, if you really want something, a dark web tutorial is 30 seconds away. And from what I've heard from a client, Ozempic on the dark web is roughly 5x cheaper.

Re: GLP-1 drugs: An economic disruptor? (2024)

#319

Post by otterley »

bdzr wrote: post #285
otterley wrote: post #266

Earlier quoted context omitted.

I don’t know if it’s the nature of the products themselves, or if it’s because they’re vastly cheaper and more accessible. There’s a natural limit to the number of cookies to be had from Grandma before she says “that’s enough,” vs being able to get 64 at the local market anytime you want for a pittance.

> I don’t know if it’s the nature of the products themselves Isn't this what you were just arguing it was not 10 minutes earlier?

I’m wondering if it’s a little of both. I’m not a nutritionist, but one operating theory I’ve read is that many processed foods are manufactured in such a way that they make you feel less full than a homemade equivalent would.

Re: GLP-1 drugs: An economic disruptor? (2024)

#320

Post by IgorPartola »

ForTheKidz wrote: post #218
dumbfounder wrote: post #11

Earlier quoted context omitted.

Malls around DC are crazier than ever. But I am not sure if people are spending money or not.

It's straight up miserable to be in mclean/tysons between october and february. Truly it is america's asshole. And yes, people conspicuously consume more than ever. I think this is likely not true of most malls, though, the shopping culture here is just nuts.

Because in a lot of places there is nothing else fun to do. There is in particular nothing to do for teenagers. They aren’t welcome at most places and the mall is about the only place where you can go and (a) not be run out of there and (b) not have your parents worried that you are getting up to no good. So teenagers grow up in the malls and as adults are habitually going back.
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