As someone who has struggled with suicidal ideation while working in the tech industry for over a decade, I do wonder if the insane culture of Bay Area tech has a part to play.
Besides the extreme hustle culture mindset, there's also a kind of naive techno-optimism that can make you feel insane. You're surrounded by people who think breaking the law is OK and that they're changing the world by selling smart kitchen appliances, even while they're exploiting workers in developing countries for cheap tech support and stepping over OD victims outside their condo.
This mindset is so pervasive you really start to wonder if you're crazy for having empathy or any sense of justice.
I have no special insight except to guess that going from being an obviously brilliant student at Berkeley to a cut-throat startup like OpenAI would be a jarring experience. You've achieved everything you worked your whole life for, and you find you're doing work that is completely out of whack with your morals and values.