I still remember Craig Silverstein being asked what his biggest mistake at Google was and him answering "Not pushing for ECC memory." Google's initial strategy (c. 2000) around this was to save a few bucks on hardware, get non-ECC memory, and then compensate for it in software. It turns out this is a terrible idea, because if you can't count on memory being robust against cosmic rays, you also can't count on the soft…
ECC memory can't eliminate the chances of these failures entirely. They can still happen. Making software resilient against bitflips in memory seems very difficult though, since it not only affects data, but also code. So in theory the behavior of software under random bit flips is well... Random. You probably would have to use multiple computers doing the same calculation and then take the answer from the quorum. I…
The Apollo missions (or was it the Space Shuttle?) did this. They had redundant computers that would work with each other to determine the “true” answer.