311–320 of 1001 posts
Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!
I'd argue that has a lot more to do with the election uncertainty being over with. This is incredibly promising news, but probably not enough to account for SP500 jumping 400 points this morning.
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The Ebola vaccine required -80 C storage as well and they got it into literal war zones. It’s a difficult problem, but a solved one.
Ebola was localized. COVID-19 is not. I like your optimism, and what you said isn't incorrect about Ebola at the time, but I don't think it's correct about our current situation. How many locations globally have this level of refrigeration? Given that there would be high demand for it, wouldn't prices on any available refrigerators exceed what even the most altruistic companies and organizations could pay? This still…
- https://www.gavi.org/vaccineswork/cold-supply-hot-demand
I don't have much more on that front, but it's worth a look to see what well developed agencies are aiming at.
Great. This is the one that has to be kept ultra cold. Hoping for good news about some of the other vaccines in Phase 3 trials soon. The vaccine reportedly needs to be held in storage at -94° Fahrenheit (-70°c), and will last for only 24 hours at refrigerated temps between 35.6° and 46.4°. (about 2° to 8° c) from https://www.fiercepharma.com/manufacturing/pfizer-moderna-s-...
Pretty much any biology lab in the world has -80 °C fridges. For shipping, a styrofoam container with some dry ice is probably good enough.
Earlier quoted context omitted.
Ebola was localized. COVID-19 is not. I like your optimism, and what you said isn't incorrect about Ebola at the time, but I don't think it's correct about our current situation. How many locations globally have this level of refrigeration? Given that there would be high demand for it, wouldn't prices on any available refrigerators exceed what even the most altruistic companies and organizations could pay? This still…
> Ebola was localized. COVID-19 is not You could easily localize COVID-19, just make a vaccination passport. No entry to a country if you're not vaccinated. > How many locations globally have this level of refrigeration Almost all developer countries, urban centres, where majority of people live anyway.
At -80C?
Edit: There are hardly storage places right now for these temperatures.
I'm feeling a deep-seated wave of relief that I never thought possible. Like waking up from a year-long nightmare. Thank God.
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Just because you don't find layoffs as ideologically palpable as shedding (some or all) the inefficiency incurred by covid doesn't make the markets wrong. There's potential for a huge gain in efficiency here. The stock market is fundamentally a long bet (if you want to short the entire market you invest in things outside it). Of course the market is exited at the long term prospects of that. Also, you're being a litt…
> There's potential for a huge gain in efficiency here ... Of course the market is exited at the long term prospects of that. IMHO this supports the OPs point, which is that the stock market in its current incarnation does not care about the lives of human beings. Which is unacceptable. We collectively have enough creativity and intelligence figure out how to have a stock which can not only reflect corporate profit b…
I do agree that using the stock market as an indicator of quality of life, general well being of human beings or anything else than the financial viability of publicly traded companies is not a very good idea. That's a frequent mistake made by financial journalists and politicians alike, however, especially during election season.
Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?
The latest data (preprint, not peer reviewed etc etc) mention memory B and T cells up to 8 months after recovery from the illness. This means that an immunity of one year is probably likely. This would be probably enough to quench the spread, but not to eradicate the virus.
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The latest data (preprint, not peer reviewed etc etc) mention memory B and T cells up to 8 months after recovery from the illness. This means that an immunity of one year is probably likely. This would be probably enough to quench the spread, but not to eradicate the virus.
I think we can eradicate it by contact tracing. With 90% efficiency it will be extremely tough for the virus to spread. For any new cases you simply test everyone in the vicinity of the infected person. But I don't think even that will be necessary. 90% efficiency reduces R so much, it will probably die out on its own. The real problem is mutations that are not covered by the vaccine. If it mutates as efficiently as…