Around 2 years ago now, I took the plunge and bought myself an Ergodox EZ split island keyboard. Quite franky, it is the biggest quantum leap in the ergonomic experience of interacting with a computer I have seen since learning Vim. It is comfortable, effortless and fast. If you spend any significant time interacting with computers it is a complete no brainer to invest in optimising the IO channel between your brain…
The Ergodox is not perfect, though. I think it has too many thumb keys (blindly copying Kinesis); they take up space but you can't really take advantage of them. Going from a staggered layout to ortholinear was quite the struggle for me. I endured and "got it", but I know a lot of people aren't going to have the patience.
Ultimately I like this article because it shows that hand-wired keyboards are quite practical. The author went overboard making it look nice, but you can build yourself a very nice keyboard with an Arduino, some switches, diodes, and wire, and a 3D printer. It won't look as nice, but you can get every single detail perfect.