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Gene-Engineered Mouth Bacteria

lanternbioworks.com

301–310 of 312 posts

Re: Gene-Engineered Mouth Bacteria

#301
post #269

Earlier quoted context omitted.

I'm 40 years old. Never had cavities. I eat plenty of sugar.

Scientist lurkers in the thread take note. We have a couple for the first cohort for testing to see if their mouth biome differs from base population. Inquiring minds want to know!

Anecdotally, none of my girlfriends seem to have developped any similar immunity. If the article is right, my flora should have replace theirs on the long run, no?

Re: Gene-Engineered Mouth Bacteria

#302
post #296
post #244

Earlier quoted context omitted.

If your friends are looking for feedback, you can pass on that at least one person on the internet finds it in very bad taste for them to describe the delay in treatment as a "civilizational embarrassment" while planning to charge $20k for a dose. The pricing point seems equally a civilizational embarassment to me.

I can easily imagine someone who don't brush their teeth ever to spend like $1000 a year for cavity repairs (because, well, I did). So I guess $20k is near to the market price you could expect people to pay for a lifetime (with refills and no cavities guarantee) for this product. If $20k it too much for you, just wait for cheaper generics.

That's not the point — the critique (as I understand it) is about the way in which it's presented.

Re: Gene-Engineered Mouth Bacteria

#303

Earlier quoted context omitted.

Or just rinse (water pick even better) with a dilute bleach solution (0.25%). Make the solution fresh each time or every 24 hours, since sodium hypochlorite tends to decompose easily. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292655/

Don't use bleach when you can easily make hypochlorous acid. Hypochlorous acid is bleach but acidified and much safer to the human body than bleach. Bleach is thousands of times more toxic to humans at the same HOCl concentration. You suggest using an OCl- concentration of 2500 ppm which would be extremely high for an equivalent therapeutic use of hypochlorous acid. You can easily use a 10 times lower concentration o…

Do you have any research papers supporting those assertions? At least with low-concentration bleach, it's been tested numerous times in RCTs without any harmful effects, besides bad taste. It's also proven effective, or at least as effective as prescription-based chlorhexidine mouthwash.

I'm interested in reading more, because I find diluting the bleach solution to be annoying and would obviously damage dyed fabrics if spilled.

Re: Gene-Engineered Mouth Bacteria

#304
post #183

Earlier quoted context omitted.

Yes! Rinsing your mouth REGULARLY after meals does a lot to prevent further cavities. Also a diet high in animal meat and fats (cheese, butter etc.) helps strengthen teeth https://www.healthygoods.com/blogs/news/dr-weston-prices-die... And cutting out sugars - especially fructose - avoids diabetes. Some people who are lactose intolerant cut out lactose, and some people prone to celiac disease cut out gluten. Sometime…

> Yes! Rinsing your mouth REGULARLY after meals does a lot to prevent further cavities. So basically drinking water?

Not drinking

Rinsing your mouth, like sloshing it around to make sure it gets rid of all the gunk. Maybe flossing too.

Re: Gene-Engineered Mouth Bacteria

#305

Earlier quoted context omitted.

I have very strong (and ugly) teeth. The few "cavities" that I had, were actually made by dentists (they do that, y'know), and have resulted in a couple of crowns. Otherwise, my teeth are great. I now have a dentist that doesn't make cavities, and she seems almost disappointed, when she checks me. But gum care is every bit as important as tooth care (take it from me, you don't want a gum-scraping), and that is why I…

> The few "cavities" that I had, were actually made by dentists (they do that, y'know) You are the only person I have ever heard entertain this idea, so it would be better to spell out how this happened than assume everyone knows it.

I can certainly attest that I've had dentists damage my teeth on more than one occasion.

Re: Gene-Engineered Mouth Bacteria

#306
post #296
post #244

Earlier quoted context omitted.

If your friends are looking for feedback, you can pass on that at least one person on the internet finds it in very bad taste for them to describe the delay in treatment as a "civilizational embarrassment" while planning to charge $20k for a dose. The pricing point seems equally a civilizational embarassment to me.

I can easily imagine someone who don't brush their teeth ever to spend like $1000 a year for cavity repairs (because, well, I did). So I guess $20k is near to the market price you could expect people to pay for a lifetime (with refills and no cavities guarantee) for this product. If $20k it too much for you, just wait for cheaper generics.

Capitalism at its finest. A civilization should be measured at how it treats the poorest. By selling such an incredible cure (if it's really working) for thousands of dollars makes it impossible for the low-income class to purchase.

Re: Gene-Engineered Mouth Bacteria

#307
post #162

Earlier quoted context omitted.

Does brushing and mouthwash really eliminate your microbiome? I heard it does precious little. Most of the microorganisms live below the gumline and surfaces. If that were true it would eliminate caries! Please post links

Mouthwash (WITH alcohol) daily almost completely eliminates the need for daily brushing and flossing. This was later retracted by demand of the ADA to only say "as good or better than flossing"; from here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894074/ "mouth rinses would be considered to be “at least as good as” daily flossing if the upper limit of the 90% confidence interval" there are a number of studies on…

No thanks. I'll not be using alcohol-based mouthwash. https://drugfree.org/drug-and-alcohol-news/australian-study-...

Re: Gene-Engineered Mouth Bacteria

#308

A conversation with my friend who was a dentistry student, ~2013. > [The friend, let's call her L, trying to dissuade me from drinking some fizzy drink] > J: But I won't get a cavity if the liquid doesn't touch my teeth. > L: Cavities are caused by the ensuing low ph environment, not by contact with teeth > J: Does that mean I can drink as much of it as I want as long as I rinse my mouth with water afterwards? > L, w…

Not sure that I understood what you're saying...

You drink fizzy drinks during the day, and each time that you drink you rinse your mouth with water without brushing your teeth.

And you only brush, say, before sleep, and this has reduced your cavities to zero?

thanks

Re: Gene-Engineered Mouth Bacteria

#309

Earlier quoted context omitted.

You should rinse and spit it out in the morning, don't swallow as you will be swallowing significantly more plaque from the over night build up. After initial morning cleaning swallowing should be fine.

Why would swallowing the plaque be significant?

It destroys your heart, possibly. Plaque builds up in arteries, etc. I just don't know if dietary plaque gets into the bloodstream. Don't think there are many studies. But plaque left on the teeth is known to cause heart problems and be lethal so I imagine trying to keep it out of our systems has to be better than not.

Re: Gene-Engineered Mouth Bacteria

#310
post #91

Earlier quoted context omitted.

If this is such a revolutionary technology and it is cheap to mass produce, it should be like water fluoridation and similar state funded measures that increase overall population health. I am not arguing that $20k is more than regular dental work's cost over a lifetime, in the US at least, but that it's because dental work is so expensive is why oral health is so bad worldwide,Lifestyle, sugar consumtion and the lik…

Maybe it ought to be that way. But we believe in property rights and government confiscation of property isn’t something I support. Might be the pols manage to find a way to buy the tech to give away freely to the people. Until then it’s theirs to distribute as they please until their exclusive rights expire.

I wasn't talking about confiscation, although expropriation and similar measure are common when done for a public good. Anyway in this case I think the whole product is bogus and it's mostly VC bait.
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