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Widely used chemical strongly linked to Parkinson’s disease

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Re: Widely used chemical strongly linked to Parkinson’s disease

#301

>"But in the 20th century, TCE was used for many purposes, including making decaffeinated coffee" ... This is exactly the reason I never touched decaf coffee until I found Swiss water process (SWP) decaf. It never made sense to me to use hydrocarbon solvents in a food application

Chlorinated hydrocarbons are generally the ones you want to really watch out for.

Re: Widely used chemical strongly linked to Parkinson’s disease

#302

Widely used chemical *(that was generally phased out in the 70s) linked to Parkinson's. Still important, but you don't need to start searching product labels in 2023 for it.

I'm not for panicked reporting, but in the face of the stated facts (as far as true) your comment is overly dismissive: the chemical solvent trichloroethylene (TCE)—common in soil and groundwater—increases the risk of developing Parkinson’s disease. The movement disorder afflicts about 1 million Americans, and is likely the fastest growing neurodegenerative disease in the world; its global prevalence has doubled in t…

...and as an inhaled surgical anesthetic for children

As one who went under inhaled anesthesia a dozen times or more as a child in the 70s, I can only say, "WTF?" It makes a great solvent, so let's put in anesthesia?

Re: Widely used chemical strongly linked to Parkinson’s disease

#303
post #3

When you drink your coffee without caffeine in your 30 for escaping a harm from caffeine, but end up with Parkinson in your 60+.

Given that drinking coffee lowers your risk of getting Parkinson's by up to 80%, the lack of caffeine is probably doing more for your Parkinson's risk than whatever chemicals were used to decaffeinate it.

[deleted]

Re: Widely used chemical strongly linked to Parkinson’s disease

#305

Widely used chemical *(that was generally phased out in the 70s) linked to Parkinson's. Still important, but you don't need to start searching product labels in 2023 for it.

I'm not for panicked reporting, but in the face of the stated facts (as far as true) your comment is overly dismissive: the chemical solvent trichloroethylene (TCE)—common in soil and groundwater—increases the risk of developing Parkinson’s disease. The movement disorder afflicts about 1 million Americans, and is likely the fastest growing neurodegenerative disease in the world; its global prevalence has doubled in t…

[deleted]

Re: Widely used chemical strongly linked to Parkinson’s disease

#306

Earlier quoted context omitted.

I'm not for panicked reporting, but in the face of the stated facts (as far as true) your comment is overly dismissive: the chemical solvent trichloroethylene (TCE)—common in soil and groundwater—increases the risk of developing Parkinson’s disease. The movement disorder afflicts about 1 million Americans, and is likely the fastest growing neurodegenerative disease in the world; its global prevalence has doubled in t…

...and as an inhaled surgical anesthetic for children As one who went under inhaled anesthesia a dozen times or more as a child in the 70s, I can only say, "WTF?" It makes a great solvent, so let's put in anesthesia?

as an inhaled surgical anesthetic for children and women in labor

To be fair though, the restricted audience for the administration of this particular chemical would seem to indicate considerations of safety have been applied, otherwise one would expect a more general pattern. One must suspect there are many more chemicals with similarly hard-to-test-for longterm effects in daily use, note especially the so-called 'forever chemicals' (PFAS).

What's more, dose / length of exposition makes a poison, so it's not possible to say in the abstract how a short but intense exposition of TCE stacks up against 24/7 exposition of low levels over the entire childhood. Meaning there's hope here.

Also can you be sure it was TCE you received? I remember one general anesthesia when I was maybe 9 or so and that was pretty definitely laughing gas. It might have been the same in (some of) your case(s), too.

Re: Widely used chemical strongly linked to Parkinson’s disease

#308

Earlier quoted context omitted.

...and as an inhaled surgical anesthetic for children As one who went under inhaled anesthesia a dozen times or more as a child in the 70s, I can only say, "WTF?" It makes a great solvent, so let's put in anesthesia?

as an inhaled surgical anesthetic for children and women in labor To be fair though, the restricted audience for the administration of this particular chemical would seem to indicate considerations of safety have been applied, otherwise one would expect a more general pattern. One must suspect there are many more chemicals with similarly hard-to-test-for longterm effects in daily use, note especially the so-called 'f…

Also can you be sure it was TCE you received? I remember one general anesthesia when I was maybe 9 or so and that was pretty definitely laughing gas.

I'm pretty sure they don't cut you open on nitrous oxide (that and...that stuff just wasn't nitrous). Was it TCE? I don't know, nor do I really care. What's done is done, and worrying about it isn't going to change anything. My reaction is more to the fact that there were just not a lot of fucks given back then. Rivers were open sewers, lead was in gasoline even when it was known to be a bad idea, and we put solvents in children's anesthesia.

Re: Widely used chemical strongly linked to Parkinson’s disease

#309

Earlier quoted context omitted.

yes! But I've also embarrassed myself more than once by spilling coffee (or, ahem, some other liquid) on my eider-down duvet. Moreover, the properties of a duvet cover that could keep the duvet safe from such insults -- namely, a tight weave, and water resistance -- also make it sweaty at night. While highly prized, I've decided that eider down is simply not a practical material for either my jackets nor my bedding.…

No geese are harmed in the making of eiderdown either (eiders are ducks and the down is collected from their nests, not from animals.)

...in factory settings. Confinement is a harm.

Yet I say this as a lover of fur and rabbit felt hats

Re: Widely used chemical strongly linked to Parkinson’s disease

#310

Earlier quoted context omitted.

I'm not for panicked reporting, but in the face of the stated facts (as far as true) your comment is overly dismissive: the chemical solvent trichloroethylene (TCE)—common in soil and groundwater—increases the risk of developing Parkinson’s disease. The movement disorder afflicts about 1 million Americans, and is likely the fastest growing neurodegenerative disease in the world; its global prevalence has doubled in t…

...and as an inhaled surgical anesthetic for children As one who went under inhaled anesthesia a dozen times or more as a child in the 70s, I can only say, "WTF?" It makes a great solvent, so let's put in anesthesia?

> It makes a great solvent, so let's put in anesthesia?

Literally, yes. The potency of an inhalation anesthetic is usually directly proportional to its lipid solubility. (Known as the Meyer-Overton correlation.) This is why solvents such as ether and chloroform were used as anesthetics and why N₂O is both an anesthetic and is dissolved in cream to form whipped cream.

The mechanism of inhalation anesthetics is not completely understood but it's thought that they interact with lipids in cell membranes and disrupt stuff. The better they dissolve in lipids, the lower the concentration that is needed for anesthesia.

There's a nice graph on Wikipedia: https://en.wikipedia.org/wiki/Theories_of_general_anaestheti...

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