Intermittent fasting from dawn to sunset induces anticancer response • Hacker News Board

Re: Intermittent fasting from dawn to sunset induces anticancer response

#301

Post by tbran » Fri, Oct 30, 2020, 1:03 PM UTC

DoreenMichele wrote: post #129

Melting_Harps wrote: post #96

I've been doing a 16-20 hour fast since the lockdown and WFH, and to be honest I saw a significant decrease in my overall anxiety as a result. Anxiety I often offset with significant amounts of CBD (a $100/month expense). And while there are drawbacks, I can't bench press 215lbs anymore, the overall benefits have been pretty significant that I will keep doing it. My weight was pretty erratic, given the high stress lo…

Anxiety I often offset with significant amounts of CBD (a $100/month expense). Foods containing rosemary, sage and dill are some things I find helpful with anxiety. Also licorice with real licorice extract.

But if you're considering eating licorice, don't go nuts with it. A guy recently died from eating too much [1].

From the FDA [2]:

"If you’re 40 or older, eating 2 ounces of black licorice a day for at least two weeks could land you in the hospital with an irregular heart rhythm or arrhythmia."

[1]: https://arstechnica.com/science/2020/09/rare-case-of-black-l...

[2]: https://www.fda.gov/consumers/consumer-updates/black-licoric...

Re: Intermittent fasting from dawn to sunset induces anticancer response

#302

Post by aiisjustanif » Fri, Oct 30, 2020, 1:06 PM UTC

jelliclesfarm wrote: post #216

DoreenMichele wrote: post #129

Earlier quoted context omitted.

Anxiety I often offset with significant amounts of CBD (a $100/month expense). Foods containing rosemary, sage and dill are some things I find helpful with anxiety. Also licorice with real licorice extract.

Liquorice is an adaptogen that helps balance cortisol levels and balance the adrenals. The other are merely anti inflammatory. Another effective herb for anxiety would be holy basil or tulsi. Easy to grow everywhere. Leaving a few leaves of holy basil in a copper container overnight and having a few sips in the morning on an empty stomach is my old grandmother’s remedy/morning ritual. Later when I started growing hol…

Holy basil is also used as an anti inflammatory consumable. It’s anti anxiety property has as much proof as its anti inflammatory property [1], which is to say like most herbal supplements the jury is out.

If you want to go the herbal route I think commonly used herbs with more of a medical precedent could be useful like:

- Garlic - Ginseng - Green Tea - Aloe Vera - Ginger - Chamomile

[1] Singh, S., Majumdar, D. K., and Rehan, H. M. Evaluation of anti-inflammatory potential of fixed oil of Ocimum sanctum (Holybasil) and its possible mechanism of action. J Ethnopharmacol. 1996;54(1):19-26

Re: Intermittent fasting from dawn to sunset induces anticancer response

#303

Post by theNJR » Fri, Oct 30, 2020, 1:13 PM UTC

AnonC wrote: post #90

rattray wrote: post #29

Earlier quoted context omitted.

By "we", you mean https://zerofasting.com/ ? Seems like a nice app!

I tried that app a very long time ago, and then in an update they forced users to create an online account with no local use option. I promptly removed it since I’m averse to creating online accounts when I see no good reason to do it.

I won’t pretend why you want that if you don’t pretend why we don’t offer it.

All I can say is that we are a SaaS supported product, not an ad supported one. We are highly incentivized to protect your data.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#304

Post by st1x7 » Fri, Oct 30, 2020, 1:14 PM UTC

brixon wrote: post #300

st1x7 wrote: post #269

Earlier quoted context omitted.

A very important difference is that you can't drink water during a Ramadan fast. Regardless of what you're doing with your food, deliberately dehydrating yourself is pretty much never justified.

Most articles and videos on intermittent fasting say that drinking water is fine. Artificialy sweetened drinks are also a no go.

Exactly. Maybe I wasn't clear in my comment above. My point is that most resources on intermittent fasting allow (and actually encourage) drinking a lot of water, and rightfully so. At the same time a lot of the research is done on subjects who observe Ramadan fasting and do not drink water. This difference has to influence the results in some way.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#305

Post by kranner » Fri, Oct 30, 2020, 1:14 PM UTC

AnonC wrote: post #134

kranner wrote: post #112

Earlier quoted context omitted.

I use it without an account.

Edit: Tried it again on iOS and there’s no way to proceed after the initial questions without creating an account. Deleted it again.

Sorry, my mistake. Turned out I was signed in via Apple ID.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#306

Post by DoreenMichele » Fri, Oct 30, 2020, 1:15 PM UTC

tbran wrote: post #301

DoreenMichele wrote: post #129

Earlier quoted context omitted.

Anxiety I often offset with significant amounts of CBD (a $100/month expense). Foods containing rosemary, sage and dill are some things I find helpful with anxiety. Also licorice with real licorice extract.

But if you're considering eating licorice, don't go nuts with it. A guy recently died from eating too much [1]. From the FDA [2]: "If you’re 40 or older, eating 2 ounces of black licorice a day for at least two weeks could land you in the hospital with an irregular heart rhythm or arrhythmia." [1]: https://arstechnica.com/science/2020/09/rare-case-of-black-l... [2]: https://www.fda.gov/consumers/consumer-updates/blac…

In my experience, red licorice is milder and I prefer red licorice. Black licorice is pretty harsh, in my opinion.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#307

Post by Symmetry » Fri, Oct 30, 2020, 1:15 PM UTC

mp3k wrote: post #295

shock wrote: post #256

Earlier quoted context omitted.

The Japanese researcher that got a Nobel Prize for discovering the autophagy mechanisms has a course on edx. Doesn't get much more authoritative than that.

can you please provide the link to the course?

Google seems to suggest this is it:

https://www.edx.org/course/autophagy-research-behind-the-201...

Re: Intermittent fasting from dawn to sunset induces anticancer response

#308

Post by hvidgaard » Fri, Oct 30, 2020, 1:20 PM UTC

JacKTrocinskI wrote: post #173

I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel, observing your own body and possibly talking to a doctor. I had a really big problem with acid reflux a while back after I stopped drinking alcohol. I visited many gastrologists and most of them offered little to no help, most only prescribed me drugs which was in my opinion not a solution. I finally m…

Do you happen still have the list of things your gastrologist said you could eat? I'm having a bit of reflux issue myself, and I would love to solve it purely with diet, but I don't know where to start.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#309

Post by JamesProt » Fri, Oct 30, 2020, 1:20 PM UTC

egman_ekki wrote: post #229

Barrin92 wrote: post #102

Earlier quoted context omitted.

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

> 14 subjects with metabolic syndrome who fasted (no eating or drinking) from dawn to sunset for more than 14 h daily for four consecutive weeks it says no drinking as well, so not sure about the water, but I was surprised to read it, maybe they just meant drinks other than water.

I'm almost 100% sure those 14 subjects were muslims fasting during ramadan. Which happen to be:

- 4 weeks in length

- from Dawn to sunset

- No food or drinks including water

- Easier to control group, as you cant monitor 14 people through 4 weeks and make sure they don't cheat. So the cheating is kept to the minimum because of the religious reasons.

I also assume, that those are men only. Women are not allowed to fast when on their period which happens to be once a month.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#310

Post by marketingPro » Fri, Oct 30, 2020, 1:22 PM UTC

aaaxyz wrote: post #69

marketingPro wrote: post #33

Earlier quoted context omitted.

Generally it's good to be skeptical but this- "We found a significant fold increase in the levels of several tumor suppressor and DNA repair gene protein products (GP)s at the end of 4th week during 4-week intermittent fasting (CALU, INTS6, KIT, CROCC, PIGR), and 1 week after 4-week intermittent fasting (CALU, CALR, IGFBP4, SEMA4B) compared with the levels before 4-week intermittent fasting." But why would this sudde…

Is it climate change? Is it because the stock market went up 10%? Because Saturn's orbit crossed it's periphelion? Or more seriously, could it just be the Hawtorne effect? As you pointed out, without a control group, you cannot claim that any change in your measurements are due to anything. The fact that the researchers do attribute it to fasting is just bad science and makes me doubt the rest of their findings.

If any of those happened, wouldn't the entire world see those physiological effects?

Being a bit more realistic is the hawthorne effect, which can be easy to test with follow up experiments.

My biggest takeaway isn't to do IF or cut calories, but rather it seems some phenomena was found. If you asked me if diet, fasting, etc... Would cute cancer, I'd have said NO! but this study has changed that answer to "I don't know".

I suggest that is a huge difference and benefit.