This kind of "top-to-bottom" architecture approach reminds me of Apple. They have this notion that you can't provide a good product if you control only the software or only the hardware. You need full control of both, designing in the synergies to produce a really top-notch outcome.
If you read the blogs by large shops like Google, CloudFlare, or Facebook, they do the same thing on the server side. They design the software for the failure modes of the hardware, and conversely the hardware is designed to be low cost in full knowledge that the software can tolerate high failure rates.
Why am I talking about hardware? Because in a typical n-Tier design, "The Database" is just one of the pancake layers between the metal and the Internet. Every layer matters, and every layer interacts with the others. Hearing developers call themselves "full stack" is hilarious to me. They're basically saying that they know 2 out of about 20 layers! Do they know about load balancing persistence? The security tradeoffs made by TLS 1.3 zero-RTT? Cache-control headers? Disk latencies? Automatic scale-out? Virtual machine affinity and anti-affinity rules? Backup and restore? Etc...
The original post about how various databases treat transaction isolation modes is a tiny, tiny fraction of what a typical developer ought to know about the "layers below the web server" but likely doesn't. For example, about 50-70% of bespoke software I've seen in the wild either doesn't use database indexes at all, or uses them ineffectively. About 80% of websites either do not use cache-control headers, or if they do, they'll often end up with front-end errors due to the caching layers violating the consistency of data coming in from the database. Sure, it's a maxim of the industry that cache invalidation is hard, but there are workarounds such as constructing URLs based on the content hash.
All of the fancy transaction isolation modes, to me, is wishful thinking. Get more developers to use indexes first, and then come back and teach them the esoteric stuff after that!